靶点名称: HNRNPA1
NCBI ID: G3178
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HNRNPA1
其它名称: Helix-destabilizing protein | Putative heterogeneous nuclear ribonucleoprotein A1-like 3 | hnRNP core protein A1 | OTTHUMP00000241883 | helix-destabilizing protein | heterogeneous nuclear ribonucleoprotein B2 protein | HnRNP core protein A1 | Heterogeneous nuclear ribonucleoprotein A1B protein | epididymis secretory sperm binding protein | OTTHUMP00000241891 | nuclear ribonucleoprotein particle A1 protein | Heterogeneous nuclear ribonucleoprotein A1 (isoform a) | Heterogeneous nuclear ribonucleoprotein core protein A1 | OTTHUMP00000241887 | HnRNP A1-like 3 | hnRNP-A1 | OTTHUMP00000241886 | Single-strand RNA binding protein | heterogeneous nuclear ribonucleoprotein core protein A1 | Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed | HNRNPA1 variant 1 | HNRPA1L3 | Single-strand RNA-binding protein | single-strand RNA-binding protein | HnRNP A1 | MGC102835 | Single-strand DNA-binding protein UP1 | heterogeneous nuclear ribonucleoprotein A1 | heterogeneous nuclear ribonucleoprotein A1B protein | OTTHUMP00000241885 | Heterogeneous nuclear ribonucleoprotein A1, transcript variant 2 | OTTHUMP00000241890 | HnRNP-A1 | single-strand DNA-binding protein UP1 | OTTHUMP00000241888 | putative heterogeneous nuclear ribonucleoprotein A1-like 3 | hnRNP A1 | OTTHUMP00000241884 | HnRNP core protein A1-like 3 | ALS19 | HNRNPA1 variant 2 | ALS20 | ROA1_HUMAN | UP 1 | OTTHUMP00000241889 | Heterogeneous nuclear ribonucleoprotein A1 | Heterogeneous nuclear ribonucleoprotein A1 (isoform b) | hnRNP core protein A1-like 3 | Nuclear ribonucleoprotein particle A1 protein | IBMPFD3 | Heterogeneous nuclear ribonucleoprotein B2 protein | Heterogeneous nuclear ribonucleoprotein A1, transcript variant 1 | HNRPA1

HNRNPA1是一种蛋白质,在医学研究和临床应用中具有重要的价值

在本文中,我们将探讨HNRNPA1的药物靶点或生物标志物特性,以及其在临床应用中的潜在意义。

HNRNPA1概述

HNRNPA1是人类神经元蛋白质组计划(HNGP)中的一个基因,其编码的蛋白质是一种糖蛋白,由两个结构域组成:N-端α螺旋和C-端β折叠。HNRNPA1蛋白质是由两个亚基组成的二聚体,每个亚基包含一个N-末端α螺旋和一个C-末端β折叠。

HNRNPA1的生物学功能

HNRNPA1在神经元的结构和功能中起着重要的作用。在神经元中,HNRNPA1主要表达在细胞膜上,并且与神经元的生存和凋亡密切相关。HNRNPA1的蛋白质表达水平还与神经元的突触数量和突触连接密度密切相关。

HNRNPA1的药物靶点

HNRNPA1是一个良好的药物靶点,因为它的表达水平与神经元的生存和凋亡密切相关。因此,HNRNPA1已被用作神经元功能的药物靶点,如帕金森病、阿尔茨海默病等。

HNRNPA1的生物标志物

HNRNPA1可以被用作神经元功能的生物标志物,因为它在神经元中的表达水平与神经元的功能状态密切相关。HNRNPA1的蛋白质表达水平可以用于评估神经元的生存和凋亡状态,以及神经元突触的数量和连接密度。

HNRNPA1在临床应用中的潜在意义

HNRNPA1是一个有价值的药物靶点,因为它与神经元的生存和凋亡密切相关。HNRNPA1的蛋白质表达水平可以用于评估神经元的生存和凋亡状态,以及神经元突触的数量和连接密度。因此,HNRNPA1在临床应用中具有重要的潜力,可以用于治疗神经元相关的疾病。

《HNRNPA1靶点/生物标志物调研报告》(Target / Biomarker Review Report)是利用AI技术对数百至数万篇相关科研文献进行综合分析,并经过专业人员严格审核后提供的可订制化的专业研究报告,报告涵盖与HNRNPA1相关的特定信息,包括但不限于以下内容:
•   靶点/生物标志物基本信息;
•   蛋白结构及化合物结合;
•   蛋白生物学机制;
•   靶点/生物标志物重要性
•   靶点筛选与验证;
•   蛋白表达水平;
•   疾病相关性;
•   成药性;
•   相关联合用药;
•   药化试验;
•   相关专利分析;
•   靶点开发优势与风险...
研究报告有助于课题/项目申请、药物分子设计、研究进展汇报、研究论文发表、专利申请等。如果您希望获得该报告的完整版,请与我们联系: BD@silexon.ai

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