Disease

Mantle Cell Lymphoma

About the Disease
Mantle Cell Lymphoma, also known as malignant lymphoma, lymphocytic, intermediate differentiation, diffuse, is related to lymphoma and burkitt lymphoma. An important gene associated with Mantle Cell Lymphoma is ATM (ATM Serine/Threonine Kinase), and among its related pathways/superpathways are Cellular responses to stimuli and Prolactin Signaling. The drugs Cyclophosphamide and Cytarabine have been mentioned in the context of this disorder. Affiliated tissues include b cells, lymph node and t cells, and related phenotypes are lymphadenopathy and b-cell lymphoma

Common Targets
CD74 | G999 | G4318 | FOXO1 | CDKN2B | G4609 | PIK3CB | Ribonucleoside-diphosphate reductase | CD6 | G598 | HOXD8 | HOXA9 | CHEK1 | GATD3 | IL10 | NPM1 | PRMT5 | MUC16 | CDK5 | CDK5/p25 | SYK | BMX | CD99 | FLT3 | NUP214 | G1/S-specific cyclin-E (nonspecified subtype) | MIR155 | CDK9/Cyclin T1 | CDK9 | XIAP | FAM221A | G836 | SF3B1 | ASXL3 | GATA6 | CD38 | MNX1 | NF-kappaB (NFkB) | HSF1 | G7157 | G4170 | FCGR3A | EBF3 | VPS11 | TNFSF10 | VWA5B1 | FAM186A | PCDH8 | CCNT1 | MS4A1 | FLRT2 | SIRPA | ADA | CACNG8 | RB1 | DCX (DDB1-CUL4-X-box) E3 protein ligase complex | NRN1 | Adenosine deaminase (nonspecified subtype) | IL2 | GABRG3 | ZNF503 | FOXP4 | CCND3 | TGFB1I1 | CD22 | G2309 | G472 | LARS1 | SH3BP4 | Proteasome Complex | SPIDR | JUP | BLK | Histone deacetylase (nonspecified subtype) | BCL2A1 | CRBN | CCNE1 | CDK4/Cyclin D | FABP5 | CDK1/Cyclin B | IL17F | PRKCB | RAD51 | CREBBP | EIF5A | ITGA5 | SUMO activating enzyme complex | PIM1 | KLF2 | CDK20 | JAM3 | CDKN1B | HMBS | SYT6 | IKZF3 | ADRA1D | Poly [ADP-ribose] polymerase (nonspecified subtype) | Janus Kinase (nonspecified subtype) | MLF1 | SLC5A5 | CDK2/Cyclin A | Cyclin D (nonspecified subtype) | G596 | ROR1 | ZNF423 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | ADAM12 | CD47 | CSTF2 | Ikzf1 | PIK3CG | G2146 | TNFRSF13C | TNFRSF17 | G238 | ALB | G1029 | CD19 | IRF8 | SLC4A4 | CDK6/Cyclin D3 | BIRC5 | HNF4A | AMP-activated protein kinase (AMPK) | Cyclin A (nonspecified subtype) | TGFBR2 | CDK1 | C2CD2L | CDK2/Cyclin E | DPAGT1 | ATR | ADAMTS18 | G2475 | HIF1A | BTK | HDAC6 | G595 | RBM34 | ELANE | CDK7 | CDK12 | CD72 | CD37 | SOX11 | PIK3CA | PMAIP1 | G5243 | CCDC97 | H2AX | G207 | HYOU1 | DNAH14 | CD3 Complex (T Cell Receptor Complex) | CDK6 | TNFRSF13B | CDH13 | CDK2 | CDK4 | PTPN6 | DNA-Directed DNA Polymerase Complex | Heat shock protein 90 (nonspecified subtype) | CD5 | CDK4/Cyclin D3 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | PIK3CD | CDK4/Cyclin D1 | Protein Kinase B (PKB/Akt) (nonspecified subtype) | MYD88 | CSNK1E | Tubulin | THBS1 | Cyclin B (nonspecified subtype) | FCGR2B | HDAC1 | G4851 | CXCR5 | G9429 | Integrin alpha4beta1 (VLA-4) receptor | FKBP1A | G7852 | G7124 | FAM110B | IKZF1 | KDR | PSMB5

疾病靶点研报
Mantle Cell Lymphoma

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