Acute Infantile Liver Failure

About the Disease
Liver Failure, Infantile, Transient, also known as acute infantile liver failure due to synthesis defect of mtdna-encoded proteins, is related to infantile liver failure syndrome and spinocerebellar ataxia, autosomal recessive 21, and has symptoms including icterus and vomiting. An important gene associated with Liver Failure, Infantile, Transient is TRMU (TRNA Mitochondrial 2-Thiouridylase), and among its related pathways/superpathways is tRNA-uridine 2-thiolation (mammalian mitochondria). Affiliated tissues include liver and skin, and related phenotypes are hepatomegaly and feeding difficulties in infancy

Common Targets
RINT1 | TRMU | NR1H4 | LARS1 | NBAS

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