Disease

Spinocerebellar Ataxia Type 1

About the Disease
Spinocerebellar Ataxia 1, also known as spinocerebellar ataxia type 1, is related to spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2 and spinocerebellar ataxia 7, and has symptoms including muscle spasticity, abnormal pyramidal signs and abnormality of extrapyramidal motor function. An important gene associated with Spinocerebellar Ataxia 1 is ATXN1 (Ataxin 1). The drugs Glutamic acid and Lithium carbonate have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, eye and cerebellum, and related phenotypes are peripheral neuropathy and progressive cerebellar ataxia

Common Targets
ATXN7 | KCNN3 | RAI1 | KCND3 | Voltage-Gated Sodium Channel Complex | Glutamate Transporter (nonspecified subtype) | CHRNA7 | Sodium channel (nonspecified subtype) | ATXN3 | TBP | ATN1 | CACNA1A | HTT | ATXN1 | ATP2B3 | KCNA1 | ATXN2 | TDP1

疾病靶点研报
Spinocerebellar Ataxia Type 1

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