Spinocerebellar Ataxia Type 8

About the Disease
Spinocerebellar Ataxia 8, also known as spinocerebellar ataxia type 8, is related to spinocerebellar ataxia, autosomal recessive 8 and mitochondrial dna depletion syndrome 7, and has symptoms including muscle spasticity, tremor and abnormal pyramidal signs. An important gene associated with Spinocerebellar Ataxia 8 is ATXN8OS (ATXN8 Opposite Strand LncRNA). Affiliated tissues include spinal cord, eye and cerebellum, and related phenotypes are hyperreflexia and nystagmus

Common Targets
ATXN8OS | KCND3 | Voltage-Gated Sodium Channel Complex | Glutamate Transporter (nonspecified subtype) | Sodium channel (nonspecified subtype) | NKX6-2 | KLHL1 | SYNE1

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