Disease

Allan-Herndon-Dudley Syndrome

About the Disease
Allan-Herndon-Dudley Syndrome, also known as ahds, is related to pelizaeus-merzbacher disease and hyperthyroidism, and has symptoms including ataxia and clonus. An important gene associated with Allan-Herndon-Dudley Syndrome is SLC16A2 (Solute Carrier Family 16 Member 2), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Angiopoietin-like protein 8 regulatory pathway. The drugs Carbamide peroxide and Glycerin have been mentioned in the context of this disorder. Affiliated tissues include thyroid, brain and skeletal muscle, and related phenotypes are axial hypotonia and ataxia

Common Targets
THRB | SLC16A2 | Histone deacetylase (nonspecified subtype)

疾病靶点研报
Allan-Herndon-Dudley Syndrome

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