Neuromyelitis Optica

About the Disease
Neuromyelitis Optica, also known as devic syndrome, is related to transverse myelitis and neuritis. An important gene associated with Neuromyelitis Optica is AQP4 (Aquaporin 4), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Antineoplastic Agents, Immunological and Daratumumab have been mentioned in the context of this disorder. Affiliated tissues include Umbilical Cord, spinal cord and eye, and related phenotypes are optic neuritis and visual loss

Common Targets
THRB | C1S | TNPO3 | MGLL | IL7 | GTF2I | FCGRT | TNFSF13 | CD58 | AQP4 | NOTCH4 | IL7R | AQP4-AS1 | TNFSF13B | FCGR3A | PAX4 | ADA | MS4A1 | LOC105375911 | Adenosine deaminase (nonspecified subtype) | STAT4 | FAAH | LOC105375914 | PRKCH | Serine protease (nonspecified subtype) | Complement Complex | ABHD6 | SIX4 | PTPN22 | HLA-DQB1 | HLA-C | IL6R | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | TNFRSF17 | TNXB | CD19 | HLA-DRB1 | BTK | THRA | RGMA | HLA-B | PRRC2A | BANK1 | TYK2 | G5243 | G2099 | TRIM42 | C5 | HLA-DQA1 | ESR2 | Complement component 1q

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