Restrictive Cardiomyopathy

About the Disease
Restrictive Cardiomyopathy, also known as familial restrictive cardiomyopathy, is related to cardiomyopathy, familial restrictive, 2 and cardiomyopathy, familial restrictive, 1. An important gene associated with Restrictive Cardiomyopathy is TNNI3 (Troponin I3, Cardiac Type), and among its related pathways/superpathways are Cardiac conduction and Cytoskeletal Signaling. The drug Hydroxyurea has been mentioned in the context of this disorder. Affiliated tissues include heart, lung and liver, and related phenotypes are muscle and cardiovascular system

Common Targets
SS18 | HCN4 | ZNF841 | FLNC | PSEN2 | TMEM43 | TNNC1 | ZNF277 | ILK | CACNA1C | TARM1 | TNNI3 | EYA4 | TNNT2 | DSP | LDB3 | JUP | ABCC9 | MYL2 | PSMA8 | VCL | TTN | MYL3 | JPH2 | PDLIM3 | MYOM1 | TRPM4 | CRYAB | MYH6 | Myosin (nonspecified subtype) | SCN5A | TPI1 | DGKI | PEX1 | ACTC1 | TPM1 | ANK2 | MYH7 | BAG3 | DMD | MYBPC3 | SMO | DES | KCNH2 | TRIM37

Note: If you'd like to get a target analysis report for Restrictive Cardiomyopathy, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Restrictive Cardiomyopathy at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Adrenoleukodystrophy, X-linked | Polycythemia | Eccrine Porocarcinoma | Multifocal Motor Neuropathy | Gnathodiaphyseal Dysplasia | Speech Disorders | Epidermolysis Bullosa Acquisita | Acute Lung Injury | Ocular Surface Squamous Neoplasia | Hyperacusis | Focal Facial Dermal Dysplasia | Poretti-Boltshauser Syndrome | Preaxial Polydactyly | Spinocerebellar Ataxia Type 23 | Progressive Familial Intrahepatic Cholestasis Type 3 | Parkinson Disease 6, Autosomal Recessive Early-onset | Diabetic Macular Edema | Periventricular Leukomalacia | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Ulcerative Colitis | Leukoencephalopathy, Progressive Multifocal | Apert Syndrome | Amish Infantile Epilepsy Syndrome | IMAGe Syndrome | Hypohidrotic Ectodermal Dysplasia | Irritable Bowel Syndrome | Ovarian Hyperstimulation Syndrome | Neuroectodermal Tumors, Primitive | Usher Syndrome | Hemorrhagic Disorders | Exocrine Pancreatic Insufficiency | Hereditary Xerocytosis | Hemolytic Anemia | Neurocutaneous Melanocytosis | Dystonia Musculorum Deformans | Syphilis | Congenital Bile Acid Synthesis Defect | Glycogen Storage Disease Type 4 | Johanson-Blizzard Syndrome | Skin Papilloma | Gastritis, Atrophic | Waardenburg Syndrome Type 2 | Diabetic Encephalopathy | Megalencephaly | Atrial Septal Defect | Gastritis | Primary Lateral Sclerosis | Liver Failure | Pheochromocytoma | Paronychia | Impulse Control Disorder | Renal Hypomagnesemia 3 | Coffin-Siris Syndrome | Vitamin D Deficiency | Hyperparathyroidism, Secondary | Cornelia De Lange Syndrome | Persistent Mullerian Duct Syndrome | Keratitis | Diabetic Nephropathy | Amebiasis | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Neutrophilia | Borjeson-Forssman-Lehmann Syndrome | Infectious Diarrhea | Esophageal Adenocarcinoma | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Vascular Calcification | Primary Sclerosing Cholangitis | Benign Familial Neonatal Convulsions | Myelofibrosis | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Pleomorphic Xanthoastrocytoma | Diabetes | Otopalatodigital Syndrome Type 2 | Periventricular Nodular Heterotopia | X-linked Acrogigantism | Hemochromatosis | Zellweger Syndrome | Monilethrix | Diarrhea | Episodic Ataxia Type 2 | Low Phospholipid Associated Cholelithiasis | Hepatitis E | Pyloric Stenosis, Infantile Hypertrophic | Infertility, Male | Tetraplegia | Diabetic Neuropathy | McKusick Type Metaphyseal Chondrodysplasia | Richter's Syndrome | Agoraphobia | Adenosine Deaminase 2 Deficiency | Hypertensive Retinopathy | Hypothyroidism | Diabetes Type 1 | Hartsfield Syndrome | Usher Syndrome Type IIC | Wolfram Syndrome | Meleda Disease | Bietti Crystalline Dystrophy | Oral Lichen Planus | Carcinoid Syndrome | Dementia, Vascular | Babesiosis | Prolymphocytic Leukemia | Varices | Amblyopia | Cancer, Prostate | Vascular Cognitive Impairment | Leukodystrophies | Coenzyme Q10 Deficiency | Angina Pectoris | Mountain Sickness | Diabetes Insipidus, Neurogenic | Progressive Familial Intrahepatic Cholestasis | Stomatitis | Pituitary Disorders | Adenoma, Pituitary | Familial Isolated Hyperparathyroidism | Paraplegia | Thyroid Dyshormonogenesis | Metanephric Adenoma | Bartter Syndrome | Antisynthetase Syndrome | Smoldering Myeloma | Oculocutaneous Albinism Type 2 | Hypolipoproteinemia | Asphyxia Neonatorum | Graves Disease | Primary Hyperoxaluria | Encephalocele | Benign Recurrent Intrahepatic Cholestasis 1 | Enlarged Vestibular Aqueduct | Patent Ductus Arteriosus | Stuttering | Perivascular Epithelioid Cell Tumor | Blau Syndrome | Fetal And Neonatal Alloimmune Thrombocytopenia | Meckel-Gruber Syndrome | Calcium Pyrophosphate Deposition Disease | Metachromatic Leukodystrophy | Juvenile Polyposis | Amelogenesis Imperfecta | Lattice Corneal Dystrophy | Chudley-McCullough Syndrome | Subacute Sclerosing Panencephalitis | Osteopathia Striata With Cranial Sclerosis | Autosomal Recessive Spastic Paraplegia Type 75 | Pulmonary Alveolar Proteinosis | Bronchiolitis | Localized Scleroderma | Persistent Fetal Circulation | Myasthenia | Non-small Cell Lung Cancer | Hermansky-Pudlak Syndrome | Conjunctivitis | Hereditary Hemorrhagic Telangiectasia Type 2 | Atherosclerosis | Parvovirus B19 Infection | Inflammatory Myopathy | Keloid | Nicolaides-Baraitser Syndrome | Motion Sickness | Sarcosinemia | Hemorrhage | Amenorrhea | Hypersomnia | Spitzoid Melanoma | Eczema | Skin Carcinoma | Partington Syndrome | Onchocerciasis | Metatropic Dysplasia | Fatty Aldehyde Dehydrogenase Deficiency | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Addison Disease | Currarino Syndrome | Encephalopathy, Glycine | Schuurs-Hoeijmakers Syndrome | Stevens-Johnson Syndrome | Robinow Syndrome | Inborn Errors Of Metabolism | Renal Failure | Intestinal Pseudo-obstruction | Splenomegaly | Spondylo-ocular Syndrome | Haim-Munk Syndrome | Neovascular Glaucoma | Primary Torsion Dystonia | Porphyria, Acute Intermittent | Cat Eye Syndrome | Meningioma, Benign | Peripheral Neuropathy | Hereditary Spastic Paraplegia | Mast Cell Leukemia | Melanoma | Tyrosinemia | Mabry Syndrome | Chorea-acanthocytosis | Retinitis | Avellino Corneal Dystrophy | Hypoproteinemia, Hypercatabolic | Fabry's Disease | Lipodystrophy | Pseudomyxoma Peritonei | Hyperphosphatasia With Intellectual Disability Syndrome 4 | DOCK8 Immunodeficiency Syndrome | Hereditary Spherocytosis | Pemphigus Foliaceus | Acrodermatitis | Stroke, Ischemic | Leukemia-lymphoma, Adult T-cell | Endocarditis | Glaucomatocyclitic Crisis | Carcinoma In Situ | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Leiomyosarcoma | Carcinoid Tumor | Fowler's Syndrome | Colitis, Collagenous | Pneumoconiosis | Chiari Malformation Type I | Hypertension, Pulmonary | Sleep Disorder | Crimean-Congo Hemorrhagic Fever | Klippel-Feil Syndrome | Tricho-hepato-enteric Syndrome | Vitamin B12 Deficiency | Plasma Cell Leukemia | Glutaric Aciduria Type 2 | Triphalangeal Thumb-polysyndactyly Syndrome | Panniculitis | Uveitis, Anterior | Arthritis | Non-bullous Congenital Ichthyosiform Erythroderma | Malonyl-CoA Decarboxylase Deficiency | Erythropoietic Protoporphyria | Episodic Ataxia | Pulmonary Veno-occlusive Disease | Alveolar Capillary Dysplasia | Dengue Shock Syndrome | Leukoplakia, Oral | Aspergillosis | Thrombosis | Bicuspid Aortic Valve | Rhabdomyosarcoma | Melanoma, Malignant | Pathological Gambling | Gray Platelet Syndrome | Melanocytic Nevus | Nemaline Myopathy 10 | Myoclonus | Vasculitis | Glomerulonephritis, Membranous | Lipid Storage Diseases | Stroke, Hemorrhagic | GATA2 Deficiency | Bacterial Meningitis | Sorsby Fundus Dystrophy | Phenylketonuria II | Central Pain Syndrome | Alkaptonuria | Polycythemia Vera | Osteitis | Hyperinsulinemic Hypoglycemia | 3-methylcrotonyl-CoA Carboxylase Deficiency | Hepatic Steatosis | GLUT1 Deficiency Syndrome | Primary Pigmented Nodular Adrenocortical Disease | Acute Kidney Injury | Brachydactyly | X-linked Charcot-Marie-Tooth Disease | Castleman Disease | Odonto-onycho-dermal Dysplasia | CDKL5 Deficiency Disorder | Osmotic Demyelination Syndrome | Spinocerebellar Ataxia Type 14 | Hyperinsulinemia | Chronic Lymphocytic Leukemia | Thanatophoric Dysplasia | Cholesteryl Ester Storage Disease | Tangier Disease | Zygomycosis | NGLY1 Deficiency | Pontocerebellar Hypoplasia | Ependymoma | Arteriovenous Malformations | Acromesomelic Dysplasia | Spermatocele | Peeling Skin Syndrome Type B | Extramammary Paget's Disease | Wolcott-Rallison Syndrome | Dermatitis Herpetiformis | Myositis, Focal | Schnyder Crystalline Corneal Dystrophy | Tibial Muscular Dystrophy | Xeroderma Pigmentosum | Androgenic Alopecia | Hydrolethalus Syndrome | Spinocerebellar Ataxia Type 31 | Osteogenesis Imperfecta Type I | Chronic Neutrophilic Leukemia | Ornithine Transcarbamylase Deficiency | Synovitis | Muscular Dystrophy | Combined Pituitary Hormone Deficiency | Pernicious Anemia | Tatton-Brown-Rahman Syndrome | Macular Corneal Dystrophy Type 1 | Long QT Syndrome Type 2 | Lymphoproliferative Disease, X-linked | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Esophagitis | Pulmonary Stenosis | Trachoma | Hepatitis | Mandibuloacral Dysplasia With Type A Lipodystrophy | Hyperlipidemia, Familial Combined | Cholestasis, Intrahepatic | Alopecia Totalis | Meesmann Corneal Dystrophy | Wilson's Disease | Methemoglobinemia | Carcinoma, Small Cell | Progressive Encephalopathy-optic Atrophy Syndrome | Unverricht-Lundborg Syndrome | Brooke-Spiegler Syndrome | Metabolic Diseases | Teratozoospermia | Osteoporosis-pseudoglioma Syndrome | SAPHO Syndrome | GAPO Syndrome | Chediak-Higashi Syndrome | Phosphoglycerate Dehydrogenase Deficiency | Bone Marrow Necrosis | Trichomegaly | HUPRA Syndrome | Early Infantile Epileptic Encephalopathy | Li-Fraumeni Syndrome | PHARC Syndrome | Communication Disorders | Amelanotic Melanoma | Cutis Laxa | Pseudohypoparathyroidism Type 2 | Ebstein Anomaly | Retinal Coloboma | Nail Disorder, Nonsyndromic Congenital | Infantile Refsum Disease | Myositis | Epidermolysis Bullosa Dystrophica | Stroke | Harlequin Ichthyosis | Spinocerebellar Ataxia Type 13 | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Cannabis Abuse | Encephalopathy, Hepatic | Glanzmann Thrombasthenia | Fascioliasis | Relapsing Polychondritis | Weill-Marchesani Syndrome | Hepatitis D | Hereditary Coproporphyria | Ectopia Lentis, Isolated, Autosomal Recessive | Panic Disorder | Chromosome 8q21.11 Deletion Syndrome | Bursitis | Chondrosarcoma | Spondylosis | Werner's Syndrome | Progressive Myoclonic Epilepsy | Jacobsen Syndrome | Okihiro Syndrome | Herpes Genitalis | Neuromyotonia | Galactosemia | Takenouchi-Kosaki Syndrome | Granuloma Annulare | Restrictive Dermopathy | Mitochondrial Cytopathy | Barakat Syndrome | Anorectal Fistula | Myoclonic Epilepsy With Ragged Red Fibers | Basal Ganglia Disease, Biotin-responsive | Mitochondrial DNA Depletion Syndrome 13 | Deafness, Dystonia, And Cerebral Hypomyelination | Paracoccidioidomycosis | Spinocerebellar Ataxia Type 7 | Lyme Disease | Familial Dysautonomia | Hemolytic Uremic Syndrome, Atypical | Carpal Tunnel Syndrome | Behcet's Disease | Protein C Deficiency | Hemimegalencephaly | Stiff-man Syndrome | PASLI Disease | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Glomerulonephritis, Membranoproliferative | Mucolipidosis | Rash | Kernicterus