Disease

Personality Disorders

About the Disease
Avoidant Personality Disorder, also known as anxious personality disorder, is related to narcissistic personality disorder and personality disorder, and has symptoms including sleep disturbances, photophobia and personality changes. An important gene associated with Avoidant Personality Disorder is PIR (Pirin), and among its related pathways/superpathways are Digestion and absorption and Monoamine transport. The drugs Dopamine and Fluoxetine have been mentioned in the context of this disorder. Affiliated tissues include cingulate cortex, cortex and brain, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Common Targets
ALDH2 | GABA(A) receptor | SLC6A4 | GRIN2B | DRD2 | KCNIP4 | COL25A1 | COMT | MAOA

疾病靶点研报
Personality Disorders

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