Disease

Hyperinsulinism-hyperammonemia Syndrome

About the Disease
Hyperinsulinemic Hypoglycemia, Familial, 6, also known as hyperinsulinism-hyperammonemia syndrome, is related to hyperinsulinemic hypoglycemia, familial, 2 and hyperinsulinemic hypoglycemia, familial, 1. An important gene associated with Hyperinsulinemic Hypoglycemia, Familial, 6 is GLUD1 (Glutamate Dehydrogenase 1), and among its related pathways/superpathways are Metabolism and Disorders of transmembrane transporters. The drugs Tocopherol and DL-alpha-Tocopherol have been mentioned in the context of this disorder. Affiliated tissues include liver, and related phenotypes are reactive hypoglycemia and asymptomatic hyperammonemia

Common Targets
SLC25A36

疾病靶点研报
Hyperinsulinism-hyperammonemia Syndrome

Note: If you'd like to get a target analysis report for Hyperinsulinism-hyperammonemia Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Hyperinsulinism-hyperammonemia Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Myofibrillar Myopathy | Leber Congenital Amaurosis | Osteosclerosis | Peters-plus Syndrome | Carpenter Syndrome | Chronic Kidney Disease | Hypotonia-cystinuria Syndrome | Keratoconjunctivitis | Medulloblastoma | Camptocormia | Pure Red Cell Aplasia | Nail-Patella Syndrome | Dystonia | Cancer, Colon | Weill-Marchesani Syndrome | Sponastrime Dysplasia | Sialoadenitis | Keloid | Spondylometaphyseal Dysplasia | Polyomavirus Nephropathy | Babesiosis | Lymphoma | Bone Giant Cell Tumor | Thrombosis | Analgesia | Warsaw Breakage Syndrome | Zimmermann-Laband Syndrome | Spinocerebellar Ataxia Type 28 | Anal Fissure | Heart Block | Chronic Thromboembolic Pulmonary Hypertension | VEXAS Syndrome | Aicardi-Goutieres Syndrome | Osteogenesis Imperfecta Type VI | Aplasia Cutis Congenita | Stroke, Hemorrhagic | Posterior Polar Cataract | Dystonia Musculorum Deformans | Spina Bifida | Oculocutaneous Albinism Type 2 | Vulvovaginitis | Insulin Resistance | Primary Ovarian Insufficiency | Joubert Syndrome 2 | Multicystic Renal Dysplasia | Mitochondrial DNA Depletion Syndrome 13 | Retinal Diseases | Scleroderma | Chronic Myelomonocytic Leukemia | Intellectual Disability, Autosomal Dominant 5 | Localized Scleroderma | Mucolipidosis Type II | Spinocerebellar Ataxia Type 5 | Meconium Ileus | Inflammatory Myofibroblastic Tumor | Renal Tubular Acidosis | Left Ventricular Noncompaction | Glioblastoma | Trachoma | Proopiomelanocortin Deficiency | Hyperparathyroidism | Disseminated Superficial Actinic Porokeratosis | Juvenile Myelomonocytic Leukemia | Intermittent Claudication | Coenzyme Q10 Deficiency | Stiff-man Syndrome | Juvenile Xanthogranuloma | Purpura | Pneumothorax | Erythematotelangiectatic Rosacea | Hyperglycemia | Patent Ductus Arteriosus | Dyslexia | Spinocerebellar Ataxia Type 31 | Autosomal Recessive Congenital Ichthyosis | Thyroiditis, Autoimmune | Stomatitis | KBG Syndrome | Pachyonychia Congenita | Chordoma | Amyotrophic Lateral Sclerosis, Juvenile | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Brugada Syndrome 1 | Myocardial Infarction | Cryoglobulinemia | Relapsing Polychondritis | Fibrosarcoma | Cherubism | Tularemia | Postpartum Depression | Renal Dysplasia | Hypodontia | Proteasome-associated Autoinflammatory Syndrome 2 | Stromal Corneal Dystrophy | VACTERL Association | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Sepiapterin Reductase Deficiency | Necrotizing Autoimmune Myopathy | Adenocarcinoma | Asperger Syndrome | Familial Glucocorticoid Deficiency | Hypolipoproteinemia | Pseudohermaphroditism | Atelosteogenesis Type 2 | Skin Papilloma | Bicuspid Aortic Valve | Myelomeningocele | Glomerulonephritis, Membranous | Tuberculosis | Oculocutaneous Albinism Type 1 | Nephronophthisis | 3-methylcrotonyl-CoA Carboxylase Deficiency | Colon Adenoma | Microcephaly, Seizures, And Developmental Delay | Porphyria, Variegate | Chylothorax, Congenital | Astrocytoma | Tyrosinemia | Metatropic Dysplasia | Congenital Hereditary Endothelial Dystrophy Type II | Cousin Syndrome | Arteriosclerosis | Paraganglioma | Asphyxia Neonatorum | Ornithine Transcarbamylase Deficiency | Alstrom Syndrome | Cramp Fasciculation Syndrome | Leukodystrophies | H Syndrome | Lymphedema | Sleep Apnea, Obstructive | Papillorenal Syndrome | Bronchitis | Angiosarcoma Of The Breast | Schizotypal Personality Disorder | Antiphospholipid Syndrome | Carcinoma, Small Cell | Synpolydactyly | Botulism | Perivascular Epithelioid Cell Tumor | Bethlem Myopathy | Guanidinoacetate Methyltransferase Deficiency | Agnathia-Otocephaly Complex | Retinal Dystrophy | Hydrolethalus Syndrome | FG Syndrome | Mood Disorder | Cystinuria | Amish Infantile Epilepsy Syndrome | Idiopathic Multicentric Castleman Disease | Chondrodysplasia Punctata 1, X-linked Recessive | Gastroenteritis, Eosinophilic | Japanese Encephalitis | Mesothelioma, Malignant | Progressive Familial Intrahepatic Cholestasis Type 2 | Pemphigus Vulgaris | Hyperparathyroidism, Primary | Primary Erythromelalgia | Myoclonus-dystonia Syndrome | Persistent Truncus Arteriosus | Myotonia | Neurotoxicity | Schwannomatosis | Acute Lung Injury | Central Retinal Artery Occlusion | Spinocerebellar Ataxia Type 17 | Trismus-pseudocamptodactyly Syndrome | Fascioliasis | Gastroenteritis | Anorexia Nervosa | Renal Medullary Carcinoma | Pseudo-pseudohypoparathyroidism | Lymphoproliferative Disease, X-linked | Craniofrontonasal Syndrome | Metabolic Syndrome | Persistent Mullerian Duct Syndrome | Neuromuscular Disorders | Herpes Genitalis | Autoimmune Disease | Nasodigitoacoustic Syndrome | Alagille Syndrome | Autosomal Recessive Bestrophinopathy | Obesity, Morbid | Erdheim-Chester Disease | Congenital Bile Acid Synthesis Defect | Dermatofibrosarcoma | Colitis, Lymphocytic | Spinal Muscular Atrophy Type 3 | Patent Foramen Ovale | Congenital Stationary Night Blindness | Cerebrotendinous Xanthomatosis | Spinocerebellar Ataxia Type 1 | Fuchs Heterochromic Iridocyclitis | Diabetic Nephropathy | Hepatitis, Alcoholic | Cholangitis | Coronary Restenosis | Pneumonia, Viral | Migraine | Parapsoriasis | T-cell Lymphoma, Subcutaneous Panniculitis-like | Gallstones | GNE Myopathy | Congenital Lipoid Adrenal Hyperplasia | Epidermodysplasia Verruciformis | Congenital Sodium Diarrhea | Acute Leukemia | Neuroblastoma | Chondrosarcoma | Rheumatic Heart Disease | Hemochromatosis | Ventricular Septal Defect | Familial Exudative Vitreoretinopathy | Mucolipidosis | Argininosuccinic Aciduria | Hyperparathyroidism, Secondary | Cornelia De Lange Syndrome | Multiple System Atrophy | Carcinoma In Situ | Hepatitis D | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Carbonic Anhydrase VA Deficiency | Pyruvate Kinase Deficiency | Cardiomyopathy, Dilated, 1L | Charcot-Marie-Tooth Disease Type 2T | Myosin Storage Myopathy | Neuronal Ceroid Lipofuscinosis | Porencephaly | Gynecomastia | GM2-gangliosidosis AB Variant | Behcet's Disease | Cat Eye Syndrome | Acromegaly | Encephalopathy, Glycine | Dysmorphophobia | Charcot-Marie-Tooth Disease, Type 1A | Retinal Dystrophy, Early-onset Severe | Viral Meningitis | Agammaglobulinemia | Rotor Syndrome | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Colorectal Adenoma | Osteonecrosis | Borjeson-Forssman-Lehmann Syndrome | Fontaine Progeroid Syndrome | Gastrointestinal Disorders | Uveitis | Long QT Syndrome Type 3 | Lymphoproliferative Disorders | Waldenstrom Macroglobulinemia | Rett Syndrome | Isobutyryl-CoA Dehydrogenase Deficiency | Methemoglobinemia | Epidermolysis Bullosa Dystrophica | Primary Pigmented Nodular Adrenocortical Disease | Wolfram Syndrome | Snyder-Robinson Syndrome | HUPRA Syndrome | Spondyloepiphyseal Dysplasia Tarda, X-linked | Autonomic Neuropathy | Maple Syrup Urine Disease | Noonan Syndrome-like Disorder With Loose Anagen Hair | Asthma | Epilepsy Of Infancy With Migrating Focal Seizures | Greenberg Dysplasia | Glutathione Synthetase Deficiency | Cardiomyopathy, Hypertrophic | Nager Acrofacial Dysostosis | Facioscapulohumeral Muscular Dystrophy Type 2 | Anemia | Trimethylaminuria | Cerebrovascular Disorders | Restless Legs Syndrome | Glycogen Storage Disease Type 0 | Nance-Horan Syndrome | Hepatitis, Chronic | Polymicrogyria | Ligneous Conjunctivitis | Fibrosis | Celiac Disease | Spinocerebellar Ataxia Type 38 | Heart Failure | Asplenia | Okihiro Syndrome | Leukoplakia, Oral | Carcinoid Tumor | Hereditary Mixed Polyposis Syndrome | Blepharophimosis Syndrome | Macrophagic Myofasciitis | Angioimmunoblastic T-cell Lymphoma | AIDS | Communication Disorders | Endometriosis | Potocki-Shaffer Syndrome | Congenital Aniridia | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Pancreatitis | 3-hydroxy-3-methylglutaric Aciduria | Pulmonary Tuberculosis | Spondylocarpotarsal Synostosis Syndrome | Premature Ejaculation | Colitis, Microscopic | Cirrhosis | Wolff-Parkinson-White Syndrome | Sarcoma | Angiomyolipoma | Sporadic Inclusion Body Myositis | Alcoholism | Papilloma | Anti-NMDA Receptor Encephalitis | Infertility | Lennox-Gastaut Syndrome | Antithrombin III Deficiency | Multicentric Carpotarsal Osteolysis Syndrome | Glycogen Storage Disease Type 1 | Trichuriasis | Imerslund-Grasbeck Syndrome | Mucolipidosis Type IV | Inflammatory Linear Verrucous Epidermal Nevus | Pontocerebellar Hypoplasia | Chronic Mucocutaneous Candidiasis | Brachydactyly | IMAGe Syndrome | Dyslipidemia | Familial Partial Lipodystrophy | Vaginitis | Netherton Syndrome | Cancer, Breast | Restrictive Dermopathy | Prolidase Deficiency | Coma | Tinea | Ileitis | Periodontitis | Molybdenum Cofactor Deficiency | Pleural Tuberculosis | HELLP Syndrome | Adrenal Insufficiency | Tinea Versicolor | Sporadic Hemiplegic Migraine | Blepharo-cheilo-odontic Syndrome | Osteonecrosis Of The Jaw | Familial Pheochromocytoma-paraganglioma | HANAC Syndrome | Gingivitis | Facioscapulohumeral Muscular Dystrophy Type 1 | Congenital Nephrotic Syndrome | Hypertrophy | Ichthyosis, X-linked | Congestive Heart Failure | Diabetes Insipidus, Neurogenic | Apraxia | Silver-Russell Syndrome | Cutaneous Angiosarcoma | Acanthosis Nigricans | Vasculitis | Protein S Deficiency | Pierpont Syndrome | Pheochromocytoma | Nephritis, Interstitial | Endometrial Hyperplasia | Hidradenitis | Esotropia | Acne | Myositis, Focal | Bullous Pemphigoid | Arrhythmogenic Right Ventricular Cardiomyopathy | Acute Coronary Syndrome | Pitt-Hopkins Syndrome | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Mabry Syndrome | Neurofibromatosis Type 1 | Diabetes Gestational | Aneurysm, Abdominal Aortic | Cataract | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Roberts Syndrome | Seizures-scoliosis-macrocephaly Syndrome | DOCK8 Immunodeficiency Syndrome | Adult Polyglucosan Body Disease | Congenital Myasthenic Syndrome | Microphthalmia, Syndromic 7 | Bernard-Soulier Syndrome | Eclampsia | Progressive Familial Intrahepatic Cholestasis Type 3 | Urticaria | Atrial Septal Defect | Galactosemia | Corticobasal Syndrome | Endometritis | Beta-Propeller Protein-associated Neurodegeneration | Mitochondrial DNA Depletion Syndrome | Hypertension, Renovascular | Thalassemia, Beta | Wolfram Syndrome 2 | Alpers Syndrome | Scoliosis | Nicolaides-Baraitser Syndrome | Dermatomyositis | Iron Metabolism Disorders