Disease

Hypokalemia

About the Disease
Hypokalemia, also known as potassium deficiency, is related to gitelman syndrome and hypokalemic periodic paralysis, type 1. An important gene associated with Hypokalemia is SLC12A3 (Solute Carrier Family 12 Member 3), and among its related pathways/superpathways are Glucose / Energy Metabolism and Metabolism of steroids. The drugs Prednisolone phosphate and Prednisolone acetate have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and smooth muscle, and related phenotypes are homeostasis/metabolism and renal/urinary system

Common Targets
NR3C2 | SLC12A2 | MIR6863 | SLC12A3 | KCND3 | KCNJ16 | SCNN1B | FCGR3A | SCN4A | KCNA5 | CLDN10 | WNK1 | RET | SLC12A1 | OPRK1

疾病靶点研报
Hypokalemia

Note: If you'd like to get a target analysis report for Hypokalemia, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Hypokalemia at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Hodgkin Lymphoma | Choroiditis | Trichuriasis | Heavy Chain Disease | Metabolic Syndrome | FG Syndrome | DRESS Syndrome | Hyperparathyroidism | Tyrosinemia Type 1 | Bipolar Disorder | Zellweger Syndrome | Epilepsy Of Infancy With Migrating Focal Seizures | Diabetes Insipidus | Fascioliasis | Oral Lichen Planus | Dupuytren Disease | Hypotonia-cystinuria Syndrome | Congenital Central Hypoventilation Syndrome | Chromosome 9q34.3 Deletion Syndrome | Charcot-Marie-Tooth Disease Type 4E | Non-proliferative Diabetic Retinopathy | Congenital Stationary Night Blindness | Sarcosinemia | Hemolytic Uremic Syndrome | Osteomyelitis | Ligneous Conjunctivitis | Hemimegalencephaly | Craniosynostosis | Basal Ganglia Disease | Leri Pleonosteosis | Cancer, Kidney | Purpura | Episodic Ataxia | Hepatic Adenomatosis | Maple Syrup Urine Disease | Acute Coronary Syndrome | Methylmalonic Acidemia | Rhabdomyosarcoma | Milk Allergy | Polycystic Ovary Syndrome | Waardenburg Syndrome Type 4A | Autosomal Recessive Spastic Paraplegia Type 35 | Asplenia | Speech Disorders | Pigment Dispersion Syndrome | Mabry Syndrome | Cocaine-Related Disorders | Spastic Paraplegia Type 7 | Cardiomyopathy, Peripartum | Ocular Albinism Type 1 | Burn-McKeown Syndrome | Neurocutaneous Melanocytosis | Congenital Bile Acid Synthesis Defect | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Ectopia Lentis, Isolated, Autosomal Recessive | Coronary Restenosis | Ectrodactyly | Chloridorrhea, Congenital | Lichen Planus | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Trismus-pseudocamptodactyly Syndrome | Asthma, Exercise-induced | Acute Myeloid Leukemia | Carbonic Anhydrase VA Deficiency | Tenosynovial Giant Cell Tumor | Hypersomnia | Familial Advanced Sleep Phase Syndrome | Necrotizing Autoimmune Myopathy | Osteogenesis Imperfecta Type VI | Sulfite Oxidase Deficiency | Porphyria, Variegate | Poretti-Boltshauser Syndrome | Motion Sickness | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Hypermetropia | Rhabdoid Tumor | Gangliosidosis, GM1 | Epidermal Nevus Syndrome | Non-small Cell Lung Cancer | Charcot-Marie-Tooth Disease Axonal Type 2N | Spinocerebellar Ataxia Type 8 | Hepatitis A | Nail Disorder, Nonsyndromic Congenital | Cerebellofaciodental Syndrome | Amyloidosis | McCune-Albright Syndrome | Pain | Allergic Contact Dermatitis | Cardiomyopathy, Dilated, 1L | Distal Myopathy | Kallmann Syndrome | Smoldering Myeloma | Optic Neuropathy | Neuroleptic Malignant Syndrome | Hypercholesterolemia | Peritonitis | Hemangioma | Chiari Malformation Type I | Leukemia-lymphoma, Adult T-cell | Sarcoidosis, Pulmonary | Pre-eclampsia | Keratitis | Hemolytic Uremic Syndrome, Atypical | Hepatitis C, Chronic | Pseudo-pseudohypoparathyroidism | Hennekam Lymphangiectasia-lymphedema Syndrome | Glomerulonephritis, Membranoproliferative | Early Infantile Epileptic Encephalopathy | Sarcoma, Alveolar Soft Part | Traboulsi Syndrome | Nephritis, Interstitial | Silver-Russell Syndrome | Eclampsia | Hypothalamic Obesity | 5-oxoprolinase Deficiency | Chondromyxoid Fibroma | Alazami Syndrome | Nanophthalmos | Autism | Intestinal Obstruction | Spinocerebellar Ataxia Type 40 | Meier-Gorlin Syndrome | Mucormycosis | Peripheral T-cell Lymphoma | Arthritis, Psoriatic | Endometritis | Adenylosuccinate Lyase Deficiency | Bladder Exstrophy | Hereditary Xerocytosis | Meningococcal Meningitis | Ollier Disease | Keratosis, Seborrheic | Spondyloarthritis | Aplastic Anemia | Tricho-hepato-enteric Syndrome | Nevus | Headache | Malaria, Cerebral | Esophagitis, Eosinophilic | Sturge-Weber Syndrome | Allan-Herndon-Dudley Syndrome | Microcephaly | Pericarditis | Hepatoblastoma | Papulopustular Rosacea | Nephropathy | Hypogammaglobulinemia | Cystitis, Interstitial | Gitelman Syndrome | Aspergillosis | Glycogen Storage Disease Type 1 | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | C3 Glomerulopathy | Otopalatodigital Syndrome Type 2 | Retinoschisis | Craniofacial Dysostosis | Hidradenitis | High Molecular Weight Kininogen Deficiency | ADNP Syndrome | Herpes Simplex Dermatitis | Chronic Inflammatory Demyelinating Polyneuropathy | Cryptococcal Meningitis | Tetanus | GNE Myopathy | Cholangitis | Birk-Barel Syndrome | Chronic Myeloid Leukemia | Thyrotoxic Periodic Paralysis | Werner's Syndrome | Sclerosing Cholangitis | B-cell Prolymphocytic Leukemia | Blomstrand Osteochondrodysplasia | Familial Partial Lipodystrophy | Panic Disorder | Greenberg Dysplasia | Leukocyte Adhesion Deficiency Type 1 | Absence Epilepsy | Histiocytic Sarcoma | Transient Bullous Dermolysis Of The Newborn | Peeling Skin Syndrome Type B | Sporadic Hemiplegic Migraine | Hepatitis, Alcoholic | Olmsted Syndrome | Cranial Nerve Disease | Vitamin D Deficiency | Spasticity | CHARGE Syndrome | Charcot-Marie-Tooth Disease, Type 2C | Cleidocranial Dysplasia | Dyskeratosis Congenita | Empyema | Hypoplastic Left Heart Syndrome | Plasma Cell Leukemia | LMNA-related Congenital Muscular Dystrophy | Nutrition Disorders | LEOPARD Syndrome | Chorea-acanthocytosis | Vitamin A Deficiency | Leukoencephalopathy, Progressive Multifocal | Sick Sinus Syndrome 1 | Papilledema | Zollinger-Ellison Syndrome | Mood Disorder | Pierpont Syndrome | Gestational Trophoblastic Disease | Stomatitis | Autism Spectrum Disorders | Skin Papilloma | T-cell Leukemia | Pneumonia, Mycoplasma | Shprintzen-Goldberg Syndrome | Trichorhinophalangeal Syndrome | CDKL5 Deficiency Disorder | Meningioma | Fuchs Heterochromic Iridocyclitis | Bainbridge-Ropers Syndrome | Periodontitis | Auriculocondylar Syndrome | HUPRA Syndrome | Thalassemia | Hypodontia | Optic Neuropathy, Anterior Ischemic | Localized Scleroderma | Acrodermatitis | Lafora Disease | Metachromatic Leukodystrophy | Congenital Dyserythropoietic Anemia Type 1 | Citrullinemia | NGLY1 Deficiency | Christianson Syndrome | Cerebral Amyloid Angiopathy | Sleep Disorder | X-linked Charcot-Marie-Tooth Disease | Holt-Oram Syndrome | Thanatophoric Dysplasia Type 1 | Farber Disease | Lymphoproliferative Disease, X-linked | 3-methylglutaconic Aciduria | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Snyder-Robinson Syndrome | LRBA Deficiency | Borjeson-Forssman-Lehmann Syndrome | Hemochromatosis Type 1 | Meniere's Disease | Coenzyme Q10 Deficiency | Parkinsonism | Hypothyroidism | Cohen Syndrome | Pneumoconiosis | Renal Medullary Carcinoma | Cardiofaciocutaneous Syndrome | Conjunctivitis | Arthritis | Hereditary Inclusion Body Myopathy | PASLI Disease | Acromesomelic Dysplasia | Best Macular Dystrophy | Parapsoriasis | Acute Generalized Exanthematous Pustulosis | Renal Hypomagnesemia 3 | Rash | Porokeratosis | Low Phospholipid Associated Cholelithiasis | Sarcoidosis | Syncope | Osteogenesis Imperfecta Type III | Dubin-Johnson Syndrome | Megalencephaly | Hyperprolactinemia | Erysipelas | Lymphangioleiomyomatosis | Hereditary Folate Malabsorption | Thrombosis | Glycogen Storage Disease Type 1b | Atelosteogenesis Type 1 | Osteonecrosis | Glycogen Storage Disease Type 5 | Sarcoma, Endometrial Stromal | Onchocerciasis | McKusick Type Metaphyseal Chondrodysplasia | Primary Lateral Sclerosis | Vitelliform Macular Dystrophy | Guillain-Barre Syndrome | Liver Failure, Acute Infantile | Heart Septal Defects | Arterial Tortuosity Syndrome | Incontinentia Pigmenti | Familial Hemiplegic Migraine | Aneurysm, Thoracic Aortic | Charcot-Marie-Tooth Disease, Type 1A | Pneumococcal Meningitis | Iron Deficiency Anemia | Limb Girdle Muscular Dystrophy | Plasma Cell Dyscrasia | Early Infantile Epileptic Encephalopathy 13 | Infectious Diarrhea | Schindler Disease | Pityriasis Rubra Pilaris | Light Chain Amyloidosis | Cervical Dystonia | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Genitopatellar Syndrome | Stevens-Johnson Syndrome | Congenital Dyserythropoietic Anemia Type 4 | Rosacea | B-cell Chronic Lymphocytic Leukemia | Follicular Dendritic Cell Sarcoma | Phenylketonuria | Autoimmune Disease | Melanoma, Malignant | Hyperbilirubinemia | Generalized Epilepsy With Febrile Seizures Plus | Scoliosis | Chronic Myelomonocytic Leukemia | Pantothenate Kinase-associated Neurodegeneration | Discoid Lupus Erythematosus | Hypobetalipoproteinemias | Schizophrenia, Paranoid | Esophageal Carcinoma | Hereditary Hemorrhagic Telangiectasia Type 2 | Pupil Disorders | Blastoma, Pleuropulmonary | Mumps | Thrombophilia | Hyperinsulinemia | Chromosome 16p11.2 Deletion Syndrome | Systemic Mastocytosis | Torticollis | Muscle Wasting | Hyperacusis | Norrie Disease | Progressive Familial Intrahepatic Cholestasis Type 3 | Waldenstrom Macroglobulinemia | Papillorenal Syndrome | Agnathia-Otocephaly Complex | Platelet Disorders | Acute Chest Syndrome | Progressive Myoclonic Epilepsy | Sensory Neuropathy | Gaucher Disease | Retinoblastoma | Bloom Syndrome | Demyelinating Diseases | Hypereosinophilic Syndrome | Papillon-Lefevre Syndrome | Sleep Apnea | Neurofibromatosis Type 2 | Fuchs Dystrophy | Conduct Disorder | Hepatitis D | Hemorrhoids | Porphyria | Congenital Bilateral Absence Of Vas Deferens | Myasthenia Gravis | Huntington's Disease-like 2 | Bulimia Nervosa | Pleurisy | Cartilage Disorders | Spinal Muscular Atrophy Type 2 | Retinal Detachment | Rhinitis | Osteosclerosis | AIDS Dementia Complex | REM Sleep Behavior Disorder | Hypertensive Retinopathy | Pyruvate Carboxylase Deficiency Disease | TARP Syndrome | Anosmia, Congenital | Focal Segmental Glomerulosclerosis | Central Core Disease | Sleep Apnea, Central | Osteosarcoma | Gallstones | Schamberg Disease | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Sengers Syndrome | Niemann-Pick Disease | Erectile Dysfunction | Dyslipidemia | Cysticercosis | Myelomeningocele | Aicardi-Goutieres Syndrome | Neuronal Ceroid Lipofuscinosis | Hyper IgE Syndrome | Turner's Syndrome | Phosphoglycerate Dehydrogenase Deficiency | Benign Hereditary Chorea | Myopia | Primary Hyperoxaluria Type 3 | Carney Triad | HELLP Syndrome | Ulcerative Colitis | Obesity | Ileitis | Pyruvate Dehydrogenase Deficiency | Papilloma | Sialoadenitis | X-linked Creatine Transporter Deficiency | Keratosis, Actinic | Spinocerebellar Ataxia Type 20