Glaucoma, Congenital

About the Disease
Glaucoma 3, Primary Congenital, a, also known as buphthalmos, is related to gillespie syndrome and aniridia 1, and has symptoms including early vision loss An important gene associated with Glaucoma 3, Primary Congenital, a is CYP1B1 (Cytochrome P450 Family 1 Subfamily B Member 1), and among its related pathways/superpathways are Diseases of glycosylation and Diseases associated with O-glycosylation of proteins. The drugs Benzocaine and Travoprost have been mentioned in the context of this disorder. Affiliated tissues include eye, endothelial and retina, and related phenotypes are glaucoma and nevus flammeus

Common Targets
COL1A1 | FMNL2 | VAV2 | G367 | MYOC | EXPH5 | CPAMD8 | SLC4A11 | PXDN | TEK | LTBP2 | WDR36 | ANGPTL7 | ADAM9 | LRP2 | CYP1B1 | FOXC2 | KERA | FOXC1 | IL1RAPL2 | SVEP1 | VAV3 | RIGI | NTF4 | PITX2 | CNGB3 | NPHS1

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