Disease

Generalized Epilepsy And Paroxysmal Dyskinesia

About the Disease
Paroxysmal Nonkinesigenic Dyskinesia, 3, with or Without Generalized Epilepsy, also known as generalized epilepsy and paroxysmal dyskinesia, is related to benign familial infantile epilepsy and autosomal dominant nocturnal frontal lobe epilepsy, and has symptoms including absence seizures An important gene associated with Paroxysmal Nonkinesigenic Dyskinesia, 3, with or Without Generalized Epilepsy is KCNMA1 (Potassium Calcium-Activated Channel Subfamily M Alpha 1), and among its related pathways/superpathways is Potassium Channels. Related phenotypes are paroxysmal dyskinesia and eeg with spike-wave complexes (>3.5 hz)

Common Targets
PRRT2 | ADCY5 | KCNMA1

疾病靶点研报
Generalized Epilepsy And Paroxysmal Dyskinesia

Note: If you'd like to get a target analysis report for Generalized Epilepsy And Paroxysmal Dyskinesia, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Generalized Epilepsy And Paroxysmal Dyskinesia at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Meconium Ileus | Multiple Sclerosis, Primary Progressive | Homocystinuria | Cancer, Breast | Birk-Barel Syndrome | Leukemia | Alopecia | Paracoccidioidomycosis | Still Disease | Pheochromocytoma | Hyperinsulinemia | Non-small Cell Lung Cancer | Lattice Corneal Dystrophy | Myocarditis | Chordoma | Benign Hereditary Chorea | Pathological Gambling | Hypohidrotic Ectodermal Dysplasia, X-linked | Cataract | Low Phospholipid Associated Cholelithiasis | Cat Eye Syndrome | Congenital Aniridia | Hemangioblastoma | Goldenhar Syndrome | Pituitary Stalk Interruption Syndrome | Autonomic Neuropathy | Pseudohypoaldosteronism | Poikiloderma With Neutropenia | Woodhouse-Sakati Syndrome | Gastrointestinal Disorders | Spondylometaphyseal Dysplasia | Carcinoma, Transitional Cell | Neurotoxicity | Castleman Disease | Scabies | Epidermodysplasia Verruciformis | Werner's Syndrome | Emery-Dreifuss Muscular Dystrophy | Parkinsonism | Methylmalonic Aciduria And Homocystinuria, CblC Type | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Hypoparathyroidism | Corneal Neovascularization | Pilomatrix Carcinoma | Choriocarcinoma | Acrodysostosis | Malaria, Cerebral | Diarrhea | Malignant Peripheral Nerve Sheath Tumor | Diamond-Blackfan Anemia | Heavy Chain Disease | McKusick Type Metaphyseal Chondrodysplasia | Amenorrhea | Pancreatitis, Chronic | Adult Polyglucosan Body Disease | Juvenile Xanthogranuloma | Carbohydrate Metabolism Disorders | Ocular Surface Squamous Neoplasia | Encephalitis | Charcot-Marie-Tooth Disease Type 3 | Cannabis Abuse | Hypogonadism | Spinocerebellar Ataxia Type 15 | Aldosterone Synthase Deficiency | Keratopathy | Kabuki Syndrome | Spinocerebellar Ataxia Type 13 | Enlarged Vestibular Aqueduct | Chondrodysplasia Punctata 1, X-linked Recessive | Myelofibrosis | Sarcoidosis | Diabetes Insipidus, Nephrogenic | Histiocytosis | Cancer, Colon | Thrombophlebitis | Melanoma, Malignant | Hypertension, Pulmonary | Macular Degeneration | Dermatitis Herpetiformis | Pityriasis Rubra Pilaris | Rhizomelic Chondrodysplasia Punctata | Pemphigus | Medulloblastoma | Ichthyosis Bullosa Of Siemens | Syphilis | Acromicric Dysplasia | Fetal And Neonatal Alloimmune Thrombocytopenia | Skin Fragility-woolly Hair Syndrome | Hepatorenal Syndrome | Osteochondroma | Glaucomatocyclitic Crisis | Chiari Malformation Type I | Pure Autonomic Failure | Hennekam Lymphangiectasia-lymphedema Syndrome | Beckwith-Wiedemann Syndrome | Mucormycosis | Pachyonychia Congenita | Turner's Syndrome | Parapsoriasis | Membranous Nephropathy | Extramammary Paget's Disease | Lipodystrophy | Cyst | VACTERL/VATER Association | Citrullinemia | COACH Syndrome | Periodic Limb Movement Disorder | Cancer, Bladder | Spinocerebellar Ataxia Type 16 | Congenital Ichthyosiform Erythroderma | Meleda Disease | Light Chain Amyloidosis | Syncope | Brugada Syndrome 1 | Endometrial Hyperplasia | Myopia | Hypersensitivity | Dysplastic Nevus | Osteonecrosis Of The Jaw | Ocular Albinism Type 1 | Patent Ductus Arteriosus | Diabetes | Acral Lentiginous Melanoma | Blepharoconjunctivitis | Cervical Dystonia | Corticobasal Syndrome | Gastroschisis | Ovarian Sex Cord-stromal Tumor | Cardiac Sarcoidosis | Chanarin-Dorfman Syndrome | Albinism | 3C Syndrome | Robinow Syndrome | Gout | Malnutrition | Dental Caries | Fuchs Dystrophy | Lafora Disease | Intellectual Disability, Autosomal Dominant 5 | Barrett Esophagus | Nephrotic Syndrome | Azoospermia | Rubeosis Iridis | Adams-Oliver Syndrome | Hyperparathyroidism, Primary | Carcinoid Syndrome | Loeys-Dietz Syndrome | Dyslipidemia | Scleroderma | Hypodontia | Chitayat Syndrome | Placenta Previa | Babesiosis | Congenital Hemolytic Anemia | Fanconi Syndrome | Ectodermal Dysplasia | Progressive Familial Intrahepatic Cholestasis Type 3 | Optic Neuropathy | Congenital Diaphragmatic Hernia | Postpartum Depression | Hereditary Xerocytosis | Oculocutaneous Albinism Type 1 | Adrenal Insufficiency | Corneal Dystrophies, Hereditary | Cholelithiasis | Hyperacusis | Polycythemia | Urethritis | Aromatic L-amino Acid Decarboxylase Deficiency | Lymphoma, AIDS-related | Spinocerebellar Ataxia Type 20 | Anti-glomerular Basement Membrane Disease | Pulmonary Stenosis | Mosaic Variegated Aneuploidy Syndrome 2 | Myelitis | Congenital Dyserythropoietic Anemia Type 4 | Sponastrime Dysplasia | Encephalocele | Galactosemia | Primary Carnitine Deficiency | Hyperuricemia | Hepatitis, Alcoholic | Olmsted Syndrome | Hypospadias | Hemosiderosis | Androgen Insensitivity | Spinal Cord Diseases | Generalized Epilepsy And Paroxysmal Dyskinesia | Irritable Bowel Syndrome | Tic Disorder | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Acrocallosal Syndrome | Brooke-Spiegler Syndrome | Familial Retinal Arterial Macroaneurysm | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Mitochondrial Disease | Larsen Syndrome | Pierre Robin Syndrome | Pemphigoid | Hepatitis A | Leri-Weill Dyschondrosteosis | Hemolytic Uremic Syndrome | Phosphoglycerate Dehydrogenase Deficiency | Sickle Cell Anemia | Creatine Deficiency Syndrome | Basal Cell Nevus Syndrome | Tietze Syndrome | Cholangiocarcinoma | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Tricho-hepato-enteric Syndrome | Schnyder Crystalline Corneal Dystrophy | Periodontitis | Cutis Laxa | Heimler Syndrome | Xeroderma Pigmentosum Variant Type | Cenani-Lenz Syndactyly Syndrome | Hypotonia-cystinuria Syndrome | Spondylocostal Dysostosis | Currarino Syndrome | Cerebral Amyloid Angiopathy | Atopy | Crisponi Syndrome | Lichen Planus | Takayasu's Arteritis | Connective Tissue Disorders | Astrocytoma, Anaplastic | Periventricular Leukomalacia | Systemic Mastocytosis | Marfan Syndrome | Perivascular Epithelioid Cell Tumor | Mesothelioma, Malignant | Ureteropelvic Junction Obstruction | Neurofibromatosis | Lymphoma Lymphoblastic | Mitochondrial Encephalomyopathy | Kaposi Sarcoma | Spondyloperipheral Dysplasia | Gerodermia Osteodysplastica | Schizophrenia, Paranoid | Pineoblastoma | Bronchitis, Chronic | Disseminated Intravascular Coagulation | Batten Disease | Strabismus | Hyperferritinemia-cataract Syndrome | Esophagitis, Eosinophilic | Delirium | Neurofibromatosis Type 2 | Acute Lung Injury | Cervicitis | Duchenne Muscular Dystrophy | Relapsing Polychondritis | Congenital Stationary Night Blindness | Ichthyosis | Lipid Metabolism Disorders | Spinocerebellar Ataxia | Carbamoyl Phosphate Synthetase I Deficiency | Amebiasis | Urea Cycle Disorder | Vici Syndrome | Hyperuricemic Nephropathy, Familial Juvenile | Keratosis, Seborrheic | Dysequilibrium Syndrome | Metachondromatosis | Sensory Neuropathy | Renal Dysplasia | Pulmonary Capillary Hemangiomatosis | Hypertensive Retinopathy | Ovarian Hyperstimulation Syndrome | Progressive Myoclonic Epilepsy | Coffin-Siris Syndrome | Polycystic Ovary Syndrome | Aphasia | Granuloma Annulare | Carpenter Syndrome | Congenital Nystagmus | Pontocerebellar Hypoplasia | Cellulitis | Erysipelas | Cold Agglutinin Disease | Bare Lymphocyte Syndrome | Niemann-Pick Disease, Type B | Rickets | Beta-Propeller Protein-associated Neurodegeneration | Canavan Disease | Leber Hereditary Optic Neuropathy | T-cell Leukemia | Endocarditis | Incontinentia Pigmenti | Cystitis | Gynecomastia | Craniofrontonasal Syndrome | Cryptorchidism | Osteitis | Pouchitis | Infantile Refsum Disease | GLUT1 Deficiency Syndrome | Lactose Intolerance | Alcoholism | Phenylketonuria II | Aplastic Anemia | Waardenburg Syndrome Type 2E | Niemann-Pick Disease, Type A | Anodontia | Meningococcal Infections | Campomelic Dysplasia | Cirrhosis | Charcot-Marie-Tooth Disease, Type 2 | Peripheral Neuropathy | Esophageal Motility Disorders | Anuria | Pitt-Hopkins Syndrome | Schnitzler Syndrome | Renal Failure | Hereditary Mixed Polyposis Syndrome | Constipation | Chronic Lymphocytic Leukemia | Asthma | Prostatitis | Gyrate Atrophy Of The Choroid And Retina | Lymphangioma | Leishmaniasis, Visceral | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Porencephaly | Urofacial Syndrome | Combined Deficiency Of Factor V And Factor VIII | Platelet Disorders | Apparent Mineralocorticoid Excess Syndrome | Pancytopenia | Myosin Storage Myopathy | Opisthorchiasis | 3-methylcrotonyl-CoA Carboxylase Deficiency | HUPRA Syndrome | Mitochondrial Cytopathy | Cluster Headache | Autism Spectrum Disorders | Anencephaly | Esthesioneuroblastoma | Chorioretinitis | Myofibromatosis | Neurodegeneration With Brain Iron Accumulation | Retinitis Pigmentosa | Chronic Mucocutaneous Candidiasis | Hodgkin Lymphoma | Primary Erythromelalgia | Oculocutaneous Albinism Type 4 | Polycythemia Vera | Chromosome 16p11.2 Deletion Syndrome | Sensorineural Hearing Loss | Pleurisy | CDKL5 Deficiency Disorder | Hyperparathyroidism-jaw Tumor Syndrome | Glutaric Aciduria Type 2 | Cryopyrin-associated Periodic Syndromes | Cockayne Syndrome | Okihiro Syndrome | Polyarteritis Nodosa | Agnathia-Otocephaly Complex | Jawad Syndrome | Erythromelalgia | Myoclonus-dystonia Syndrome | Cantu Syndrome | Eczema | Angiosarcoma Of The Breast | Cerebral Cavernous Malformations | Keratosis, Actinic | Carney-Stratakis Syndrome | Perry Syndrome | Glioma | Bernard-Soulier Syndrome | Fucosidosis | Neural Tube Defect | Conn Syndrome | Exfoliative Dermatitis | Persistent Mullerian Duct Syndrome | Glomerulonephritis, Membranoproliferative | Wolff-Parkinson-White Syndrome | C3 Glomerulonephritis | Eosinophilic Asthma | Amyloidosis | Urolithiasis | Postaxial Polydactyly | Peyronie's Disease | Optic Neuropathy, Anterior Ischemic | C3 Glomerulopathy | Gastroenteritis | Hartsfield Syndrome | Dupuytren Disease | Rhinitis | Intestinal Hypomagnesemia 1 | Common Variable Immunodeficiency | Congenital Fiber-type Disproportion Myopathy | Nephritis, Interstitial | Multicentric Carpotarsal Osteolysis Syndrome | Smith-Lemli-Opitz Syndrome | Hypolipoproteinemia | Fowler's Syndrome | Heroin Dependence | Dysfibrinogenemia | Polymyalgia Rheumatica