Persistent Truncus Arteriosus

About the Disease
Conotruncal Heart Malformations, also known as conotruncal anomaly face syndrome, is related to velocardiofacial syndrome and heart septal defect. An important gene associated with Conotruncal Heart Malformations is NKX2-6 (NK2 Homeobox 6), and among its related pathways/superpathways is Heart development. The drugs Atezolizumab and Pirfenidone have been mentioned in the context of this disorder. Affiliated tissues include Heart, and related phenotypes are truncus arteriosus and abnormal heart valve morphology

Common Targets
GATA6

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