Disease

Abdominal Aortic Aneurysm

About the Disease
Aortic Aneurysm, Familial Abdominal, 1, also known as abdominal aortic aneurysm, is related to proteasome-associated autoinflammatory syndrome 1 and marfan syndrome. An important gene associated with Aortic Aneurysm, Familial Abdominal, 1 is AAA1 (Aortic Aneurysm, Familial Abdominal 1), and among its related pathways/superpathways are Innate Immune System and GPCR Pathway. The drugs Eplerenone and Atorvastatin have been mentioned in the context of this disorder. Affiliated tissues include abdominal aorta, smooth muscle and heart, and related phenotypes are abdominal aortic aneurysm and neoplasm

Common Targets
TRIM66 | KLF13 | FUBP1 | TOMM40 | ZNF579 | G59272 | YKT6 | ADAMTS7 | ALOX5AP | F13A1 | G7852 | ZPR1 | RFX7 | DTX2P1-UPK3BP1-PMS2P11 | SMG6 | LOC105375361 | CFD | CFP | CFI | GLIS3 | ETV5 | PGPEP1 | COL4A1 | G4318 | CERT1 | LOC107986930 | CTSS | ETS2-AS1 | JCAD | CADM2 | FAM13A | C8B | LOC105375508 | CMIP | CDKN2B-AS1 | SFXN2 | ANKS1A | MMP12 | CDKAL1 | EFEMP2 | RASA2 | SUGP1 | TGFBR1 | MYH11 | F13B | CCR2 | RABEP1 | G367 | CTSL | LOX | MNT | IPO9-AS1 | ADTRP | LINC02934 | G3569 | NLRC3 | CCDC92 | TLR2 | UBE2E2 | KAT8 | WARS2 | LOC105375716 | LOC107987412 | PRICKLE2 | ERG | IL1B | SMAD6 | FHIT | NAV1 | LOC105371060 | LOC105375733 | RPSAP52 | VCAM1 | FPGT-TNNI3K | SNX10 | HHIP | UBE2Z | LIPA | SPATA5 | MMP2 | SYN3 | PINX1 | G7422 | LOC101928004 | FGA | CFDP1 | HOXA11 | TCF21 | C8G | NMU | SMARCA4 | EYA2 | MTNR1B | ANK1 | CALCRL-AS1 | ATP2A1 | GBE1 | GCKR | TNNI3K | LOC105371116 | CFHR2 | CFHR5 | HHIPL1 | EHBP1 | G7124 | PXDN | CFHR4 | HIP1 | SPANXA1 | CLIP1 | FLRT1 | PSRC1 | LOC105377989 | RARB | LOC102724528 | TLR9 | ARAP1 | AGTR1 | G2309 | PRICKLE2-AS2 | ADCY5 | JAK2 | HOXA11-AS | FGB | NDUFAF6 | NF-kappaB (NFkB) | COL4A2 | VPS33B | QPCTL | WFS1 | LRP1 | JAZF1 | LOC105369709 | LMX1B | ZBED3-AS1 | RBMS1 | CPB2 | MMP13 | KLK1 | KCNK3 | TGFB2 | GRID1 | BDNF-AS | ASB4 | HNF1A | TIMP1 | MTCH2 | C7 | EVC2 | CCR5 | Complement Complex | CXCR2 | PEMT | ADAMTS9-AS2 | KCNQ1 | CTSC | PON1 | CPEB4 | LOC102724934 | APOE | CR1 | ELAVL4 | MACROD1 | POC5 | WDR12 | MYLK | Leukotriene B4 receptor (LTB4-R) (nonspecified subtype) | SCARB2 | INO80E | HSD17B12 | PEPD | C3 | NOTCH2 | G7099 | FIGN | DAB2IP | IL6R | SYN1 | TAL1 | C6 | FTO | GPX4 | PBRM1 | CFH | G596 | TGFB1 | TIMP2 | ZNF800 | ZBTB7B | HNF4A | ZC3HC1 | BCAP29 | DMXL2 | RMC1 | HMOX1 | SH2B3 | KIF6 | MMP1 | TCF7L2 | MAEA | TGFBR2 | C9 | CHRNA4 | SELENOP | HBEGF | LINC00907 | LOC105378797 | HNF1B | DGKB | ILRUN | ACE | BTBD9 | LPA | VTN | CALCR | DNM3 | PROX1 | IGF2BP2 | ANPEP | DNAJB4 | ZNF335 | C5orf67 | SLC30A8 | MRAS | NPC1 | ZC3H4 | LRRC53 | DCST2 | MTIF3 | PRKN | TGFB3 | CR1L | PROX1-AS1 | TLE1-DT | BDNF | ELANE | CCND2-AS1 | USP37 | MIA3 | RSPO3 | TIMP3 | CNNM2 | CD46 | ZMIZ1 | MMP10 | LOC107985979 | THADA | LDLR | LDAH | TLR3 | PLPP3 | LOC105372667 | B9D2 | GDF5 | KCNJ11 | CR2 | RPTOR | AGBL4 | BDKRB2 | LOC441087 | GNAT2 | PPARG | LOC105375047 | LOC105370275 | NRXN3 | MAP2K5 | Protein Phosphatase 2A | CFB | LINGO2 | COL3A1 | NT5C2 | SLC39A8 | PHACTR1 | C8A | SBK1 | MTHFR | TCF7L1 | LOC105375070 | ZNRF3 | TNFAIP8 | LOC107986544 | C5 | FBN1 | G1026 | PTPRD | MIR486-1

疾病靶点研报
Abdominal Aortic Aneurysm

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