Primary Hyperoxaluria Type 1

About the Disease
Hyperoxaluria, Primary, Type I, also known as primary hyperoxaluria type 1, is related to primary hyperoxaluria and chromosome 2q37 deletion syndrome, and has symptoms including bone pain An important gene associated with Hyperoxaluria, Primary, Type I is AGXT (Alanine--Glyoxylate Aminotransferase), and among its related pathways/superpathways are Gene expression (Transcription) and Metabolism of proteins. The drugs Lumasiran and Pharmaceutical Solutions have been mentioned in the context of this disorder. Affiliated tissues include kidney, eye and liver, and related phenotypes are anemia and nephrocalcinosis

Common Targets
HAO1 | LDHA | AGXT

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