Disease

Gilbert Syndrome

About the Disease
Gilbert Syndrome, also known as gilbert disease, is related to crigler-najjar syndrome, type ii and thalassemia. An important gene associated with Gilbert Syndrome is UGT1A1 (UDP Glucuronosyltransferase Family 1 Member A1), and among its related pathways/superpathways are Metabolism and Nuclear receptors meta-pathway. Affiliated tissues include liver, skin and brain, and related phenotypes are unconjugated hyperbilirubinemia and jaundice

Common Targets
UGT1A1

疾病靶点研报
Gilbert syndrome

Note: If you'd like to get a target analysis report for Gilbert Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Gilbert Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

Other Diseases

Retinopathy, Diabetic | Stickler Syndrome | Non-bullous Congenital Ichthyosiform Erythroderma | Jawad Syndrome | Autonomic Nervous System Disorders | Neurodegeneration With Brain Iron Accumulation | Atelosteogenesis Type 2 | Pneumoconiosis | Androgen Insensitivity | Kohlschutter-Tonz Syndrome | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Chudley-McCullough Syndrome | Epicondylitis | Conduct Disorder | Urolithiasis | Richter's Syndrome | Chronic Beryllium Disease | Chronic Neutrophilic Leukemia | Multiple Hamartoma Syndrome | Hereditary Spastic Paraplegia | Mucormycosis | Glycogen Storage Disease Type 9 | Epidermolysis Bullosa Dystrophica | Cirrhosis | Hypobetalipoproteinemias | Vaginitis | Focal Facial Dermal Dysplasia | Pancreatitis | Amelanotic Melanoma | Epidermolytic Palmoplantar Keratoderma | Frontotemporal Dementia | Idiopathic Multicentric Castleman Disease | Hepatitis, Chronic | Bone Giant Cell Tumor | Lathosterolosis | Cystitis, Interstitial | Dent Disease | Nephrocalcinosis | Gyrate Atrophy Of The Choroid And Retina | Steel Syndrome | Charcot-Marie-Tooth Disease | Papulopustular Rosacea | Ovarian Sex Cord-stromal Tumor | Esophageal Adenocarcinoma | Scleroderma | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Esophageal Motility Disorders | Neurofibromatosis-Noonan Syndrome | Familial Episodic Pain Syndrome | Thin Basement Membrane Disease | Saul-Wilson Syndrome | Parkinson Disease 6, Autosomal Recessive Early-onset | Aspergillosis | Atrial Septal Defect | Episodic Ataxia | Familial Dysautonomia | Constipation | Placenta Previa | Malignant Fibrous Histiocytoma | Eclampsia | Lung Diseases | Hypoparathyroidism | LRBA Deficiency | Heterotopic Ossification | VACTERL/VATER Association | Mucolipidosis Type II | Corneal Ulcer | Encephalopathy, Hepatic | Epidermolysis Bullosa Simplex | DiGeorge Syndrome | Polydactyly | Pseudohypoparathyroidism Type 1A | SAPHO Syndrome | Proctitis | Hyperphenylalaninemia | Neonatal Progeroid Syndrome | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Neurofibrosarcoma | Actinomycetoma | Cri-du-chat Syndrome | Spinocerebellar Ataxia Type 38 | Spinocerebellar Ataxia | Milk Allergy | Neurofibromatosis Type 1 | Gestational Trophoblastic Disease | Bipolar Disorder | Bacterial Meningitis | Coenzyme Q10 Deficiency | Infantile Spasm | Alstrom Syndrome | Pyoderma Gangrenosum | Carbamoyl Phosphate Synthetase I Deficiency | Pituitary Disorders | Cranioectodermal Dysplasia | Spinocerebellar Ataxia Type 28 | Renpenning Syndrome | Cluster Headache | Niemann-Pick Disease, Type B | Arthrogryposis | Kleine-Levin Syndrome | Charcot-Marie-Tooth Disease Axonal Type 2N | Esotropia | Albinism | Hemorrhage | Epiphyseal Chondrodysplasia, Miura Type | DRESS Syndrome | Oligodendroglioma | Schizotypal Personality Disorder | Metachondromatosis | Hydrocephalus, Normal Pressure | Duane Retraction Syndrome | Hairy Cell Leukemia | Epilepsy, Generalized | Presbycusis | Silicosis | PHARC Syndrome | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Splenomegaly | Osteogenesis Imperfecta | Desbuquois Syndrome | Gingivitis | Central Retinal Artery Occlusion | Sleep Apnea | Sleep Apnea, Central | Sarcoma, Endometrial Stromal | Osmotic Demyelination Syndrome | Fibronectin Glomerulopathy | Liver Diseases | Schizencephaly | Lipodystrophy | Rubinstein-Taybi Syndrome | Lymphangioma | Primary Erythromelalgia | Glaucoma, Congenital | Gastroschisis | Cutaneous Angiosarcoma | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Leber Hereditary Optic Neuropathy | Nephrotic Syndrome | Dystonia Musculorum Deformans | DNA Ligase IV Deficiency | Anal Fissure | Bartsocas-Papas Syndrome | Chronic Leukemia | Medulloblastoma | Supravalvular Aortic Stenosis | Sitosterolemia | Warsaw Breakage Syndrome | Early Infantile Epileptic Encephalopathy 13 | Oculocutaneous Albinism Type 1 | Leukocyte Adhesion Deficiency Type 1 | Epidermolysis Bullosa Simplex, Localized | Japanese Encephalitis | Familial Digital Arthropathy-brachydactyly | Macular Corneal Dystrophy Type 1 | Stiff-man Syndrome | Smith-Lemli-Opitz Syndrome | Multiple System Atrophy | Majeed Syndrome | Charcot-Marie-Tooth Disease Type 3 | REM Sleep Behavior Disorder | Oculocutaneous Albinism Type 2 | Sepiapterin Reductase Deficiency | Tyrosinemia Type 2 | Cardiofaciocutaneous Syndrome | Aphasia | Congenital Diaphragmatic Hernia | Prader-Willi Syndrome | Cystinosis | Cholangiocarcinoma | Congenital Adrenal Hyperplasia 1 | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Cerebellar Ataxia, Cayman Type | Irritable Bowel Syndrome | Acute Myeloid Leukemia | Nijmegen Breakage Syndrome | Hypodontia | Acral Lentiginous Melanoma | Depression | Asperger Syndrome | Epithelial-myoepithelial Carcinoma | Spondylosis | Lymphedema-distichiasis Syndrome | Greig Cephalopolysyndactyly Syndrome | MIRAGE Syndrome | Fascioliasis | PASLI Disease | Poretti-Boltshauser Syndrome | Sjogren Syndrome | Lamellar Ichthyosis | Paget's Disease Of The Breast | Bronchiolitis | Encephalopathy, Ethylmalonic | Optic Neuropathy, Anterior Ischemic | Neurotoxicity | Waardenburg Syndrome Type 4 | Methemoglobinemia Type IV | Microphthalmia, Syndromic 7 | Absence Epilepsy | Keratosis | Panic Disorder | Aceruloplasminemia | Gastric Atrophy | Juvenile Xanthogranuloma | Spasticity | Ureteropelvic Junction Obstruction | Agammaglobulinemia | Purpura, Thrombotic Thrombocytopenic | Headache | Toxoplasmosis | Congenital Hereditary Endothelial Dystrophy Type II | Lupus Erythematosus | Waldenstrom Macroglobulinemia | Neurocysticercosis | Citrullinemia | Fanconi Anemia | Dermatitis Herpetiformis | Methemoglobinemia | Focal Cortical Dysplasia Type 2 | Charcot-Marie-Tooth Disease Type 4D | Nephronophthisis | Familial Thoracic Aortic Aneurysm | Lyme Disease | Vitamin A Deficiency | Malnutrition | Emery-Dreifuss Muscular Dystrophy | Papillorenal Syndrome | Hypoalbuminemia | Phenylketonuria | Galloway-Mowat Syndrome | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Hyperuricemic Nephropathy, Familial Juvenile | Necrobiosis Lipoidica | Familial Glucocorticoid Deficiency | Early Infantile Epileptic Encephalopathy 1 | Usher Syndrome Type II | Pigment Dispersion Syndrome | Muscle Wasting | Keratopathy | Congenital Primary Aphakia | Vascular Cognitive Impairment | Transcobalamin Deficiency | Sleep Apnea, Obstructive | Hyperlipidemia Type V | Fibrodysplasia Ossificans Progressiva | Stroke, Hemorrhagic | Mitochondrial Cytopathy | Rolandic Epilepsy | Endocarditis | Priapism | Still Disease | Scapuloperoneal Spinal Muscular Atrophy | Chondroma | Sclerosteosis 2 | Acute Tubular Necrosis | Cancer, Skin | Spinocerebellar Ataxia Type 27 | Cancer, Prostate | Erectile Dysfunction | Coronary Restenosis | Enhanced S-cone Syndrome | Hyperostosis | Retinoblastoma | Diffuse Intrinsic Pontine Glioma | Spinal And Bulbar Muscular Atrophy | Polymyositis | Chronic Kidney Disease | Hypotrichosis Simplex | Familial Hemiplegic Migraine | Spinocerebellar Ataxia Type 15 | Parvovirus B19 Infection | Gerstmann-Straussler-Scheinker Syndrome | Lymphoma, AIDS-related | Monilethrix | Parkinsonism | Saethre-Chotzen Syndrome | Beare-Stevenson Syndrome | Werner's Syndrome | Primary Familial Brain Calcification | Progressive Osseous Heteroplasia | Hyperparathyroidism | X-linked Charcot-Marie-Tooth Disease | Myopia | Angioedema | Niemann-Pick Disease, Type C | Sarcoma | Diabetes Insipidus | Lennox-Gastaut Syndrome | Chromosome 8q21.11 Deletion Syndrome | Epithelioid Hemangioma | C3 Glomerulopathy | Hidradenitis Suppurativa | Varices | Pseudoexfoliation Syndrome | Subcortical Band Heterotopia | Vulvovaginitis | Prolidase Deficiency | Congenital Disorders Of Glycosylation | Glucagonoma | Lactose Intolerance | Vestibular Disease | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Sulfite Oxidase Deficiency | Meningococcal Infections | Smoldering Myeloma | Mitochondrial DNA Depletion Syndrome 13 | Xeroderma Pigmentosum | Gerodermia Osteodysplastica | Microcephaly | Glaucomatocyclitic Crisis | Benign Hereditary Chorea | Palsy, Cerebral | CEDNIK Syndrome | Gliosarcoma | Oculodentodigital Dysplasia | Hernia, Inguinal | Dental Caries | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Tardive Dyskinesia | Obsessive-compulsive Disorder | Leukoencephalopathy, Progressive Multifocal | Osteoarthritis | Sponastrime Dysplasia | Diabetes Mellitus, Transient Neonatal | Language Disorders | Multicystic Renal Dysplasia | Lentigo | N-acetylglutamate Synthase Deficiency | DOCK8 Immunodeficiency Syndrome | Kashin-Beck Disease | Glycogen Storage Disease Type 4 | Isovaleric Acidemia | Myofibrillar Myopathy | Barakat Syndrome | Restrictive Dermopathy | McKusick Type Metaphyseal Chondrodysplasia | Avellino Corneal Dystrophy | Proopiomelanocortin Deficiency | Multiple Sclerosis, Secondary Progressive | Lymphoma | Hypertension | Transient Bullous Dermolysis Of The Newborn | Rhabdomyosarcoma, Alveolar | Antley-Bixler Syndrome | Obesity | Hypospadias | Multiple Myeloma | Lysosomal Acid Lipase Deficiency | Turner's Syndrome | Periodontitis | Arteriovenous Malformations | Fragile X Syndrome | Myeloid Leukemia | Retinal Coloboma | Pierson Syndrome | Periventricular Nodular Heterotopia | Brooke-Spiegler Syndrome | Cheilitis | Arts Syndrome | Polymicrogyria | Triple A Syndrome | Osteitis | Pulmonary Tuberculosis | ICF Syndrome | Thrombasthenia | Harlequin Ichthyosis | Skin Papilloma | Proximal Symphalangism | Sclerosing Cholangitis | Microvillus Inclusion Disease | Tinea Versicolor | Polyomavirus Nephropathy | Inflammatory Joint Disease | Spinocerebellar Ataxia Type 8 | Neovascular Glaucoma | Urofacial Syndrome | Mosaic Variegated Aneuploidy Syndrome 2 | Cystitis | Paracoccidioidomycosis | Primary Cutaneous Amyloidosis | Oculocutaneous Albinism Type 4 | Esthesioneuroblastoma | Alpha-mannosidosis | Cushing Syndrome | Nutrition Disorders | B-cell Chronic Lymphocytic Leukemia | Leri Pleonosteosis | Hyperacusis | Photosensitivity | Chordoid Glioma | Danon Disease | Coronary Heart Disease | Leukemia | Hepatitis E | 3-methylglutaconic Aciduria | Hepatitis A | Gnathodiaphyseal Dysplasia | Glycogen Storage Disease | Multiple Sulfatase Deficiency | Arthritis, Psoriatic