Ehlers-Danlos Syndrome

About the Disease
Ehlers-Danlos Syndrome, also known as eds, is related to ehlers-danlos syndrome, classic type, 1 and ehlers-danlos syndrome, hypermobility type, and has symptoms including back pain, muscle cramp and sciatica. An important gene associated with Ehlers-Danlos Syndrome is COL3A1 (Collagen Type III Alpha 1 Chain), and among its related pathways/superpathways are Phospholipase-C Pathway and PI3K-Akt signaling pathway. The drugs Celiprolol and Adrenergic beta-1 Receptor Antagonists have been mentioned in the context of this disorder. Affiliated tissues include skin, uterus and lung, and related phenotypes are growth/size/body region and cardiovascular system

Common Targets
C1S | HGSNAT | DSE | FKBP14 | PLOD1 | ATP7A | FLNA | COL5A1 | COL1A2 | beta-Adrenoceptor (nonspecified subtype) | COL5A2 | PRKCB | AEBP1 | B4GALT7 | TNXB | ZNF469 | B3GALT6 | ADAMTS2 | C1R | SLC39A13 | BAG3 | STXBP1 | MIA3 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | CHST14 | Protein Kinase B (PKB/Akt) (nonspecified subtype) | COL3A1 | PRDM5 | COL12A1 | TAB2 | COL1A1 | FMR1

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