Multiple Sclerosis, Secondary Progressive

About the Disease
Secondary Progressive Multiple Sclerosis, also known as multiple sclerosis, secondary progressive, is related to relapsing-remitting multiple sclerosis and multiple sclerosis. An important gene associated with Secondary Progressive Multiple Sclerosis is MBP (Myelin Basic Protein), and among its related pathways/superpathways are superpathway of L-citrulline metabolism and Amino acid metabolism. The drugs Dalfampridine and Cladribine have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, brain and spinal cord, and related phenotypes are immune system and hematopoietic system

Common Targets
Carnitine O-Palmitoyltransferase 1 (CPT-1) (nonspecified subtype) | NF-kappaB (NFkB) | CYP1A1 | TRPC5 | PDE10A | Tyrosine Kinase (nonspecified subtype) | CD40 | Glutamate Transporter (nonspecified subtype) | IL7R | KIT | MTNR1B | MS4A1 | IFNG | MIR21 | ADA | G7099 | Adenosine deaminase (nonspecified subtype) | LINGO1 | ARNT | NPY | G196 | Interferon alpha/beta Receptor (nonspecified subtype) | G5133 | CYP1A2 | HLA-DQB1 | LYN | EBP | TPH2 | MIF | VMP1 | S1PR5 | LILRA3 | IL13 | LRRN1 | HLA-DRB1 | KRR1 | DPP6 | NQO1 | S1PR1 | RIPK1 | BTK | CCL20 | CYP1B1 | IL1RN | Phosphodiesterase IV (PDE4) (nonspecified subtype) | G3569 | FGFR3 | Tubulin | RGMA | Interleukin 17 (nonspecified subtype) | ESR2 | VDR | AHRR | Sodium channel (nonspecified subtype) | Voltage-Gated Sodium Channel Complex | CYSLTR1 | Integrin alpha4beta1 (VLA-4) receptor

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