Headache

About the Disease
Headache, also known as headache disorder, is related to cluster headache and migraine without aura. An important gene associated with Headache is BRCA2 (BRCA2 DNA Repair Associated), and among its related pathways/superpathways are Nuclear receptors meta-pathway and Development Ligand-independent activation of ESR1 and ESR2. The drugs Galantamine and Crofelemer have been mentioned in the context of this disorder. Affiliated tissues include eye, pituitary and brain, and related phenotypes are no effect and no effect

Common Targets
CYSLTR1 | ADCYAP1 | HTR1F | Metabotropic glutamate (mGluR) receptor (nonspecified subtype) | COMT | HTR1A | RARA | CNR1 | TGFBR3 | TSPY2 | PTGS1 | G2099 | ADORA1 | HTR2B | G5743 | MTHFR | ARHGAP6 | ADORA2B | Voltage-Gated Sodium Channel Complex | PDE10A | SLC22A3 | SCN8A | ADORA2A | Sodium channel (nonspecified subtype) | OXT | OPRD1 | SLC6A4 | HTR2A | PRRC2B | MERTK | DRD1 | CALCA | NMDA receptor | CALCRL | SCN9A | CHRNA3 | CFTR | LINC01194 | Dopamine receptor (nonspecified subtype) | FGF23 | SCN1A | HTR1B | ZFYVE28 | ADCYAP1R1 | GRID2 | alpha1-Adrenoceptor (nonspecified subtype) | PTPRN2 | Cyclooxygenase (COX) (nonspecified subtype) | HTR2C | MIF | G472 | SSTR5 | G7157 | GPR55 | OXTR | G7099 | SCN5A | ATR | OPRM1 | PER3 | HTR1D | SHMT1 | BDNF | OR14I1 | OPRK1 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | MIR4761 | SCN10A | SH2D5

Note: If you'd like to get a target analysis report for Headache, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Headache at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

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