Olmsted Syndrome

About the Disease
Mutilating Palmoplantar Keratoderma with Periorificial Keratotic Plaques, also known as olmsted syndrome, is related to olmsted syndrome, x-linked and alopecia. An important gene associated with Mutilating Palmoplantar Keratoderma with Periorificial Keratotic Plaques is PERP (P53 Apoptosis Effector Related To PMP22), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and CREB Pathway. Affiliated tissues include skin, lung and tongue, and related phenotypes are palmoplantar keratoderma and abnormal fingernail morphology

Common Targets
TRPV3 | G1956

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