Neurofibromatosis Type 1

About the Disease
Neurofibromatosis, also known as neurofibromatoses, is related to acoustic neuroma and neurofibromatosis-noonan syndrome, and has symptoms including back pain, headache and pain. An important gene associated with Neurofibromatosis is NF1 (Neurofibromin 1), and among its related pathways/superpathways are Signal Transduction and Disease. The drugs Lidocaine and Methylphenidate have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, skin and bone, and related phenotypes are Decreased viability and Decreased viability

Common Targets
G2335 | G2475 | PDGFRB | FANCD2 | RNF135 | SMARCA1 | BRCA2 | TOP1 | ARID1B | SARM1 | AKAP9 | IGF2R | MSH3 | TBX22 | FKBP1A | ZNF521 | SAMD9 | INPP4B | RASA1 | ATRX | G142 | IDH1 | MAP2K1 | G4851 | BCL11A | PRSS8 | HMGCR | NUP214 | GABA(A) receptor | JARID2 | DDX10 | GATA1 | PMS2 | BCR | TAF1 | TAF1L | TRIP11 | PPP2R1A | LRP5 | G999 | ASMTL | MTHFR | IL7R | G5243 | PAX3 | NOTCH4 | MTRR | EML4 | CASP8 | G1956 | NTRK3 | FHIT | STK36 | G4233 | TSC2 | A2ML1 | CD79A | EPHB4 | WRN | MAP3K6 | MUC1 | G4170 | STK11 | ELP1 | RNF213 | SLC19A1 | DICER1 | GATA2 | NSD1 | ERCC2 | SMARCA4 | Mitogen-Activated Protein Kinase (nonspecified subtype) | MKI67 | TET1 | G2309 | KLK10 | Eukaryotic Translation Initiation Factor 4A (eIF-4A) | G2033 | G3845 | RAF1 | BLM | FGFR4 | BCORL1 | CEP131 | PCLO | PDE4DIP | CD70 | RB1 | LRP1 | PRKDC | EPHB6 | MAML2 | BCOR | HMCN1 | CFTR | NIN | GAB2 | NF1 | APC | SOX9 | G672 | MAP2K2 | CPD | BRD3 | CCR5 | VHL | GNAS | Proteasome Complex | CUX1 | CREBBP | TYMS | GABRA5 | PTPN11 | TNK2 | CRBN | PER1 | FANCF | G472 | ARHGAP26 | FAF1 | IRF8 | NOTCH2 | SYNE1 | CCT6B | TFE3 | NLRP1 | CRLF2 | KIT | DHFR | G238 | G6776 | FANCG | RASAL3 | MTR | CD19 | AFDN | MLLT6 | G673 | SMUG1 | G6774 | MSH6 | DTX1 | BARD1 | PAK4 | Ras GTPase (nonspecified subtype) | SSX1 | MRTFA | MLLT10 | MAP3K1 | RNF43 | MAGEA1 | DCC | FANCC | PDE3A | PTPN6 | CLCN6 | DUSP9 | FBXO11 | RASAL1 | ADGRA2 | STAG2 | ETS1 | KDM6A | RASAL2 | SOS1 | NRAS | TUSC3 | SPRED1 | XPC | NCOA3 | NCOR1 | SMO | NTHL1 | PHF12 | SPEN | HRAS | ASXL1 | MYD88

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