Myotonic Disorders

About the Disease
Myotonic Disease, also known as myotonic disorders, is related to myotonic dystrophy 2 and hyperkalemic periodic paralysis, and has symptoms including muscle cramp, muscle rigidity and muscle spasticity. An important gene associated with Myotonic Disease is DMPK (DM1 Protein Kinase), and among its related pathways/superpathways is Adipogenesis. The drugs Lamotrigine and Diclofenamide have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle, pituitary and heart, and related phenotype is muscle.

Common Targets
KCNK2 | Glutamate Transporter (nonspecified subtype) | SCN4A | Voltage-Gated Sodium Channel Complex | KCNK3 | Sodium channel (nonspecified subtype) | SCN5A

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