IgA Nephropathy

About the Disease
Iga Glomerulonephritis, also known as iga nephropathy, is related to tonsillitis and glomerulonephritis. An important gene associated with Iga Glomerulonephritis is IGAN1 (IgA Nephropathy), and among its related pathways/superpathways are CCL18 signaling pathway and Mesenchymal Stem Cells and Lineage-specific Markers. The drugs Benzocaine and Tannic acid have been mentioned in the context of this disorder. Affiliated tissues include kidney, liver and heart, and related phenotypes are renal/urinary system and homeostasis/metabolism

Common Targets
VTRNA2-1 | LINC02580 | LOC105379385 | LRRC7 | AGT | DUSP3 | NRIP1 | GPR84-AS1 | FAM107B | HORMAD2 | CDH20 | AKR1C1 | G4233 | CFD | SRGAP1 | COL4A5 | LOC101928923 | AEBP2 | ICAM1 | ITGA2 | G3569 | G3479 | SUMF1 | LOC101928948 | TNFSF13 | ITGAX | NOS3 | HMOX2 | NWD2 | H1-8 | IL10RA | CCR2 | M6PR | NPHS2 | FCRLA | IL10 | IL1B | SYK | MLN | PADI6 | G3605 | WWOX | ENAH | Tyrosine Kinase (nonspecified subtype) | CNTNAP5 | HDAC7 | CFHR1 | ST6GAL1 | SGO1-AS1 | LOC105373623 | G7124 | ERG | TNFSF13B | FLT3 | CARD9 | CD38 | TNFSF12-TNFSF13 | FPGT-TNNI3K | COL9A1 | CTLA4 | IQGAP1 | LOC101927998 | MASP2 | CNTLN | CYP24A1 | TNNI3K | CFHR5 | MIR100HG | TMPRSS2 | IQSEC1 | LOC105375825 | EEF1DP3 | TLR9 | GS1-24F4.2 | AGTR1 | FCRL3 | IFNG | SETMAR | NF-kappaB (NFkB) | C1GALT1C1 | MPHOSPH6 | BACH2 | WSCD1 | GLCCI1 | RANBP9 | IL1R1 | DDR1 | LOC102724684 | BACH1 | Heme Oxygenase (HO) (nonspecified subtype) | SMARCD1 | MTMR3 | LOC105378072 | RBFOX3 | MBL2 | GPC5 | CREB3L1 | SGO1 | MIR146A | CHUK | Complement Complex | SH3RF1 | TRIM27 | LYN | NTN1 | ACOXL | SPRY2 | FCGR2A | LOC105374428 | SOX13 | TTC7A | DEFA4 | C3 | HAPSTR1 | LOC105374522 | CYP19A1 | TGFB1 | LOC105374523 | PTDSS1 | ELF1 | FCRLB | MICB-DT | PSAT1 | CFH | G596 | NOL7 | IL16 | ACCS | TNFRSF17 | C5AR1 | CCL2 | KL | LOC105372047 | Inosine 5'-monophosphate dehydrogenase (IMPDH) (nonspecified subtype) | APOL1 | RNASET2 | MPDU1 | IL12A-AS1 | SIRT5 | ACYP2 | TNFSF15 | PLA2R1 | CYP11B2 | LINC01788 | MTR | HMOX1 | COL4A3 | MIR196A2 | SETX | SERPINB7 | C1GALT1 | PSMB8 | SPATS2L | DEFA6 | IL18 | IL23R | FBXO32 | B3GALT5 | HNF1B | SGIP1 | LYPD1 | VPS50 | HCAR2 | LRRC4C | UBE3D | CX3CR1 | CAMK2N1 | IL1R2 | ABCC3 | TLCD4 | EDNRA | G4780 | GPD1L | COL4A4 | LOC105376823 | TLR1 | EEA1 | HLA-DPB2 | IL22RA1 | LINC02141 | Immunoglobulin A | GAS6 | DENND1A | SOX15 | PPARG | VAV3 | CASC15 | SCN10A | G1956 | CHI3L2 | CFB | TOP1 | ASGR1 | ABCA13 | CD40LG | LOC105372802 | C5 | FCGR2B | Asialoglycoprotein Receptor (ASGPR) (nonspecified subtype) | MYH9 | HLA-DQA1 | FBN1 | LOC101927741 | NR3C1 | GSR | BBS9 | EPHX2 | FDX1 | PADI4

Note: If you'd like to get a target analysis report for IgA Nephropathy, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of IgA Nephropathy at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

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