Disease

Chronic Pancreatitis

About the Disease
Pancreatitis, Hereditary, also known as hereditary pancreatitis, is related to tropical calcific pancreatitis and prss1-related hereditary pancreatitis. An important gene associated with Pancreatitis, Hereditary is PRSS1 (Serine Protease 1), and among its related pathways/superpathways are MicroRNAs in cardiomyocyte hypertrophy and miRNAs involvement in the immune response in sepsis. The drugs Protein C and Etanercept have been mentioned in the context of this disorder. Affiliated tissues include pancreas, bone marrow and pancreatic islet, and related phenotypes are abdominal pain and leukocytosis

Common Targets
SEMA5A | NPTX2 | G7157 | FAT1 | BNC1 | C5 | MMP3 | G7124 | IKZF1 | PCDH19 | CASR | BMP3 | CCKBR | TRPV6 | ATP8B1 | SPARC | MORC4 | RUBCNL | PRSS1 | PRSS2 | RIPPLY1 | GSTT1 | GLO1 | LOC101929279 | KRT8 | G3630 | PCDH10 | SLC26A6 | TMPRSS2 | PENK | KCNK12 | SPSB4 | CPB1 | DCX (DDB1-CUL4-X-box) E3 protein ligase complex | HOXA1 | K(ATP) Channel (nonspecified subtype) | VDR | CEL | HIC1 | GABRA1 | G4193 | Trypsin (nonspecified subtype) | CTRB2 | CD1D | Serine protease (nonspecified subtype) | AP-1 Transcription Factor Complex | PDE5A | PRKCB | CELA1 | CLDN2 | UCHL1 | GAA | GABRA5 | CFTR | GSTM1 | SERPINA12 | SPINK1 | ADAMTS2 | CTRC | GABRA2 | FUT2 | CRBN | PNLIP | ADCY1 | ABO | Voltage-Gated Calcium Channel alpha-2/delta (nonspecified subtype) | NF-kappaB (NFkB) | IL23R | MMP1 | FOS | PNLIPRP2 | ADAMTS1 | GABRA3 | CPA1 | CPA2 | AMP-activated protein kinase (AMPK)

疾病靶点研报
Chronic Pancreatitis

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