Asplenia

About the Disease
Right Atrial Isomerism, also known as ivemark syndrome, is related to heart septal defect and congenital heart defects, multiple types, 6. An important gene associated with Right Atrial Isomerism is GDF1 (Growth Differentiation Factor 1), and among its related pathways/superpathways are Nervous system development and Beta-2 adrenergic-dependent CFTR expression. The drugs Vaccines and Heptavalent Pneumococcal Conjugate Vaccine have been mentioned in the context of this disorder. Affiliated tissues include spleen, heart and liver, and related phenotypes are inguinal hernia and tetralogy of fallot

Common Targets
ORAI1 | Calcium release-activated channel (CRAC) | STIM1 | RPSA

Note: If you'd like to get a target analysis report for Asplenia, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Asplenia at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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