Other Name(s): Cyclin
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:CCOCCNC(=O)CCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
Value:=6500nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:O=C(CCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1)NCCO
Value:=6000nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:O=C(CCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1)NCC1CCCO1
Value:=2900nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:O=C(CCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1)N1CCOCC1
Value:=9700nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:CNC(=O)CCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
Value:=11000nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:O=C(Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)NS(=O)(=O)c1ccccc1
Value:=8600nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:CS(=O)(=O)NC(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Value:=14000nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:O=C(Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)N1CCOCC1
Value:=2700nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:O=C(Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)Nc1ccccc1
Value:>50000nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:CCCCNC(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Value:>50000nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:O=C(Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)N1CCCCC1
Value:>50000nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:CCN(CC)C(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Value:>50000nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:CN(C)C(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Value:=3100nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:CNC(=O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Value:=1900nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:O=C(O)CCc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
Value:=32000nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:O=C(O)CCc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Value:=17000nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:O=C(O)Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1
Value:=25000nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:CS(=O)(=O)NC[C@@H](N)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
Value:=1000nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:N[C@H](CNC(=O)CCN1CCOCC1)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
Value:=1200nM
Source:Homo sapiens
Assay:Inhibition of human recombinant PCNA interaction with PIP box protein N-5-carboxyfluorescein-SAVLQKKITDYFHPKK after 30 mins by fluorescence polarization assay
Type:IC50
SMILES:N[C@H](CNC(=O)N1CCOCC1)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1
Value:=1400nM
Source:Homo sapiens

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