Powered by AI technology, BDE-Bio combines massive literature, patent and comprehensive biological data to accurately screen and predict disease diagnosis and therapeutic targets / biomarkers. It can automatically generate target research reports with one click, making it an indispensable tool for pharmaceutical research and development.
BDE-Bio
TARGET PRECISE DISCOVERY
Product Introduction
BDE-Bio achieves precise screening and prediction of new targets by combining 24-hour continuous updates, massive literature texts, comprehensive biological databases, and large-scale multi-omics data, and can provide the basis and logic for target discovery.
1) Capture: 24-hour monitoring of Pubmed, 24 public databases (genecard, drugbank, pubchem, etc.), real-time inbound parsing.
2) Extraction: It can extract basic information about the target, protein structure, biological mechanism of the target, drug resistance of the target, disease correlation, etc.
3) Analysis: Summarize long content, generate reports with one click, recommend target points, etc.
Target Prediction
Predicting targets that can successfully enter the clinical trial stage and ensuring that lead compounds based on predicted targets can successfully break through the PCC stage within an estimated time frame.
Target-based Drug Prediction
Predicting the difficulty level of target-based drug development provides a basis for assessing the value of target exploration.
Disease-Related Target Prediction
Predicting key targets for specific diseases and provide a basis for drug development for rare diseases and difficult and complicated diseases.
Common Targets and Diseases
Targets
ABCB1 | ABCG2 | ACE2 | AHR | AKT1 | ALK | AR | ATM | BAX | BCL2 | BCL2L1 | BECN1 | BRAF | BRCA1 | CAMP | CASP3 | CASP9 | CCL5 | CCND1 | CD274 | CD4 | CD8A | CDH1 | CDKN1A | CDKN2A | CREB1 | CXCL8 | CXCR4 | DNMT1 | EGF | EGFR | EP300 | ERBB2 | EREG | ESR1 | EZH2 | FN1 | FOXO3 | HDAC9 | HGF | HMGB1 | HSP90AA1 | HSPA4 | HSPA5 | IDO1 | IFNA1 | IGF1 | IGF1R | IL17A | IL6 | INS | JUN | KRAS | MAPK1 | MAPK14 | MAPK3 | MAPK8 | MAPT | MCL1 | MDM2 | MET | MMP9 | MTOR | MYC | NFE2L2 | NLRP3 | NOTCH1 | PARP1 | PCNA | PDCD1 | PLK1 | PRKAA1 | PRKAA2 | PTEN | PTGS2 | PTK2 | RELA | SIRT1 | SLTM | SMAD4 | SOD1 | SQSTM1 | SRC | STAT1 | STAT3 | STAT5A | TAK1 | TERT | TLR4 | TNF | TP53 | TXN | VEGFA | YAP1
Diseases
Kabuki Syndrome 2 | Syphilis | Filariasis | Gastroschisis | Cholelithiasis | Osteogenesis Imperfecta | HELLP Syndrome | Systemic Lupus Erythematosus | Vici Syndrome | Dysplastic Nevus | Bartsocas-Papas Syndrome | Renal Tubular Acidosis | Hereditary Hemorrhagic Telangiectasia Type 2 | Scleroderma | Micropenis | Encephalocele | Gangliosidosis, GM1 | Bacterial Meningitis | Diverticulitis | Meniere's Disease | Bone Marrow Necrosis | Bronchitis | Oculopharyngeal Muscular Dystrophy | Bainbridge-Ropers Syndrome | Androgen Insensitivity | Irritable Bowel Syndrome | Thyrotoxic Periodic Paralysis | Cushing Syndrome | Hypercalcemia | Basan Syndrome | Retinal Degeneration | Urofacial Syndrome | Uremic Pruritus | Nemaline Myopathy 8 | Holoprosencephaly | Focal Segmental Glomerulosclerosis | Carey-Fineman-Ziter Syndrome | Papilledema | Juvenile Hyaline Fibromatosis | Chronic Lymphocytic Leukemia | Impulse Control Disorder | Phenylketonuria II | Wagner Disease | Ichthyosis, X-linked | Schistosomiasis Mansoni | Charcot-Marie-Tooth Disease | Juvenile Myoclonic Epilepsy | Antisynthetase Syndrome | Myasthenia Gravis | Endometritis | Charcot-Marie-Tooth Disease, Type 2C | Tic Disorder | Multiple System Atrophy | Priapism | Oguchi Disease-2 | Otosclerosis | Aspergillosis | Wolcott-Rallison Syndrome | Keratitis-ichthyosis-deafness Syndrome | Polycythemia | Spinocerebellar Ataxia Type 5 | Mast Cell Leukemia | Atrioventricular Septal Defect | Lymphangioleiomyomatosis | Anorectal Fistula | Impetigo | Paronychia | Allan-Herndon-Dudley Syndrome | Pyruvate Dehydrogenase Deficiency | Neurofibromatosis-Noonan Syndrome | Hemolytic Anemia | Best Macular Dystrophy | Multiple Sclerosis, Chronic Progressive | Tracheal Disorders | Parkinson's Disease | Hairy Cell Leukemia | Chondrosarcoma | Dementia, Vascular | Hashimoto Thyroiditis | Primary Progressive Aphasia | Binge Eating Disorder | Coma | TARP Syndrome | Heavy Chain Disease | Thalassemia | Cardiomyopathy, Dilated, 1L | Melanoma, Uveal | Alkaptonuria | Cornelia De Lange Syndrome | Graft-versus-host Disease | Brenner Tumor | Palsy, Cerebral | Sporadic Inclusion Body Myositis | Mandibuloacral Dysplasia With Type A Lipodystrophy | Congenital Dysfibrinogenemia | Acral Lentiginous Melanoma | Amenorrhea | Peters-plus Syndrome | Keratosis, Actinic | Hypopigmentation | Glycogen Storage Disease Type 1 | Pulmonary Sclerosing Hemangioma | Pterygium | Conn Syndrome | Primary Sclerosing Cholangitis | Epidermolysis Bullosa Simplex, Localized | Hypokalemic Periodic Paralysis | C3 Glomerulonephritis | Neutropenia | Protein S Deficiency | Fundus Albipunctatus | Bullous Pemphigoid | Metachromatic Leukodystrophy | Pulmonary Tuberculosis | Optic Atrophy 2 | Retinoblastoma | Leukemia | Smith-Kingsmore Syndrome | Asperger Syndrome | Pulmonary Veno-occlusive Disease | Glycogen Storage Disease Type 0 | Spinocerebellar Ataxia Type 8 | GLUT1 Deficiency Syndrome | Reye Syndrome | Pelvic Inflammatory Disease | Diabetes Gestational | Colitis, Collagenous | Maternally Inherited Diabetes And Deafness | Spondyloepiphyseal Dysplasia Tarda, X-linked | Aplastic Anemia | Gaucher Disease | Postpartum Depression | IgA Nephropathy | Hepatic Veno-occlusive Disease | Retinal Diseases | Vitamin D Deficiency | Liebenberg Syndrome | Chromosome 8q21.11 Deletion Syndrome | Pemphigus | Adrenomyeloneuropathy | X-linked Creatine Transporter Deficiency | Neuroma | Cyclic Vomiting Syndrome | Intestinal Hypomagnesemia 1 | Peeling Skin Syndrome Type B | Glycogen Storage Disease | Dowling-Degos Disease | Diabetic Neuropathy | Olmsted Syndrome | Cole-Carpenter Syndrome | Spina Bifida | Hepatitis E | Hepatorenal Syndrome | Thromboembolism | Arthritis, Reactive | Granular Corneal Dystrophy | Hepatitis, Autoimmune | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Congenital Muscular Dystrophy | KBG Syndrome | Osteoarthritis | Pitt-Hopkins Syndrome | Sensorineural Hearing Loss | Infectious Diarrhea | Nestor-Guillermo Progeria Syndrome | Neonatal Progeroid Syndrome | Retinopathy Of Prematurity | Meningioma, Benign | Chondroma | Optic Nerve Diseases | CHARGE Syndrome | Nasodigitoacoustic Syndrome | Fahr Disease | Glycogen Storage Disease Type 4 | Glutaric Aciduria Type 3 | Periventricular Nodular Heterotopia | Pheochromocytoma | Pseudohypoparathyroidism Type 2 | Hypermetropia | Acute Lymphocytic Leukemia | Sarcoma, Alveolar Soft Part | Transcobalamin Deficiency | Generalized Epilepsy And Paroxysmal Dyskinesia | B-cell Chronic Lymphocytic Leukemia | Spinocerebellar Ataxia Type 14 | Sertoli Cell-only Syndrome | Adenomatoid Tumor | Agnathia-Otocephaly Complex | Carbohydrate Metabolism Disorders | Hyperuricemic Nephropathy, Familial Juvenile | Stuttering | Dyslexia | Chudley-McCullough Syndrome | Conjunctivitis, Allergic | Spinocerebellar Ataxia Type 28 | Huntington's Disease | Episodic Ataxia Type 1 | Torticollis | Pituitary Dwarfism | Ligneous Conjunctivitis | Duodenal Atresia | Keratosis, Seborrheic | Oligoastrocytoma | Congenital Bile Acid Synthesis Defect | Diabetes Insipidus | Zygomycosis | Muir-Torre Syndrome | Myelofibrosis | Paracoccidioidomycosis | Lipid Storage Diseases | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Sarcosinemia | Central Pain Syndrome | Nevus | Retinal Vasculitis | Amelanotic Melanoma | Epidermolysis Bullosa Simplex, Generalized | Interstitial Lung Diseases | Whipple's Disease | Osteosclerosis | Spitz Nevus | Thyroid Dyshormonogenesis | Scleritis | Cutaneous Mastocytosis | IMAGe Syndrome | Spinocerebellar Ataxia Type 42 | Antisocial Personality Disorder | Adult Polyglucosan Body Disease | Lichen Sclerosus | Twin-to-twin Transfusion Syndrome | Varicocele | Emery-Dreifuss Muscular Dystrophy | Diffuse Mesangial Sclerosis | Adenosine Deaminase Deficiency | Chronic Granulomatous Disease, X-linked | 3-hydroxy-3-methylglutaric Aciduria | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Schizoaffective Disorder | Pantothenate Kinase-associated Neurodegeneration | Myhre Syndrome | Huntington's Disease-like 2 | Purpura | Erythema Nodosum | Platelet Disorders | Hidradenitis Suppurativa | Discoid Lupus Erythematosus | Cerebellar Ataxia, Cayman Type | Jalili Syndrome | Language Disorders | Leukoencephalopathy, Progressive Multifocal | HANAC Syndrome | Schistosomiasis | Muscle Wasting | Precocious Puberty | Neuroectodermal Tumors, Primitive | Acute Leukemia | Low Tension Glaucoma | Acute Motor Axonal Neuropathy | Hemochromatosis | Congenital Mirror Movements | Blepharospasm | Chronic Inflammatory Demyelinating Polyneuropathy | Proctitis | Glomerulonephritis, Membranoproliferative | Kindler Syndrome | Fontaine Progeroid Syndrome | Primary Hyperoxaluria Type 3 | Cryoglobulinemia | Lafora Disease | Behcet's Disease | Inflammatory Myofibroblastic Tumor | Lung Diseases | Neurofibroma | Hypertensive Nephropathy | Mohr-Tranebjaerg Syndrome | Herpes Genitalis | Nager Acrofacial Dysostosis | Creatine Deficiency Syndrome Due To AGAT Deficiency | Hypothyroidism | Arthritis, Gouty | Spinocerebellar Ataxia Type 12 | Pierson Syndrome | Specific Granule Deficiency | Hypervalinemia | Hypertensive Retinopathy | Dyslipidemia | Sporadic Hemiplegic Migraine | Intermittent Explosive Disorder | Vitamin A Deficiency | Pulmonary Stenosis | Ovarian Hyperstimulation Syndrome | Microphthalmia, Syndromic 7 | T-cell Chronic Lymphocytic Leukemia | GAPO Syndrome | Hypoalbuminemia | C3 Glomerulopathy | Meconium Ileus | Lyme Disease | Epicondylitis | Hypersensitivity Pneumonitis | Galactosialidosis | Dwarfism | Non-proliferative Diabetic Retinopathy | Paroxysmal Nocturnal Hemoglobinuria | Acrocallosal Syndrome | Creutzfeldt-Jakob Disease | Atrial Septal Defect | Silver-Russell Syndrome | Sandhoff Disease | Progressive Familial Intrahepatic Cholestasis | Congenital Fiber-type Disproportion Myopathy | Corneal Neovascularization | McKusick Type Metaphyseal Chondrodysplasia | Hypotension, Orthostatic | Chronic Beryllium Disease | Familial Thoracic Aortic Aneurysm | Lipoma | Esthesioneuroblastoma | Biotinidase Deficiency | Deafness, Dystonia, And Cerebral Hypomyelination | Netherton Syndrome | Neurodermatitis | Alopecia Totalis | Chronic Mucocutaneous Candidiasis | Alveolar Capillary Dysplasia | Varices | Glycogen Storage Disease Type 6 | Porphyria, Variegate | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Lymphomatoid Granulomatosis | Short-chain Acyl-CoA Dehydrogenase Deficiency | Cri-du-chat Syndrome | Ganglioneuroma | Epidermolysis Bullosa Simplex | Camurati-Engelmann Disease | Angiosarcoma | Myelitis | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Hereditary Sensory And Autonomic Neuropathy | Combined Pituitary Hormone Deficiency | Lymphoma, Follicular | Costello Syndrome | Spinocerebellar Ataxia Type 1 | Bietti Crystalline Dystrophy | Cardiomyopathy, Peripartum | Jawad Syndrome | Carcinoma, Signet Ring Cell | Arrhythmogenic Right Ventricular Cardiomyopathy | Cholesteryl Ester Storage Disease | Hypertension | AIDS Dementia Complex | Prolidase Deficiency | Benign Familial Pemphigus | Pseudohermaphroditism | Intracerebral Hemorrhage | Pemphigoid | Progressive External Ophthalmoplegia | Dyggve-Melchior-Clausen Disease | Cardiac Arrest | Congenital Bilateral Absence Of Vas Deferens | Alpha-mannosidosis | Farber Disease | Brooke-Spiegler Syndrome | Angiodysplasia | Antley-Bixler Syndrome | Disseminated Intravascular Coagulation | Hereditary Coproporphyria | Niemann-Pick Disease, Type B | Combined Malonic And Methylmalonic Acidemia | Brachydactyly | Overactive Bladder | Myotonia | Ependymoma | Necrotizing Autoimmune Myopathy | Usher Syndrome Type II | Oculocutaneous Albinism Type 4 | Lesch-Nyhan Syndrome | Enlarged Vestibular Aqueduct | Van Der Knaap Disease | Paroxysmal Kinesigenic Dyskinesia | Fibronectin Glomerulopathy | Ureteropelvic Junction Obstruction | Babesiosis | Ischemia | Generalized Epilepsy With Febrile Seizures Plus | Dysfibrinogenemia | Ehlers-Danlos Syndrome | Demyelinating Diseases | Peripheral Neuropathy | Chromosome 5q Deletion Syndrome | Atherosclerosis | Keratopathy | Agammaglobulinemia | Hypertriglyceridemia | Osteonecrosis Of The Jaw | AIDS | Hemoglobinopathies | Melanoma | Meningioma | Lymphedema-distichiasis Syndrome