Powered by AI technology, BDE-Bio combines massive literature, patent and comprehensive biological data to accurately screen and predict disease diagnosis and therapeutic targets / biomarkers. It can automatically generate target research reports with one click, making it an indispensable tool for pharmaceutical research and development.
BDE-Bio
TARGET PRECISE DISCOVERY
Product Introduction
BDE-Bio achieves precise screening and prediction of new targets by combining 24-hour continuous updates, massive literature texts, comprehensive biological databases, and large-scale multi-omics data, and can provide the basis and logic for target discovery.
1) Capture: 24-hour monitoring of Pubmed, 24 public databases (genecard, drugbank, pubchem, etc.), real-time inbound parsing.
2) Extraction: It can extract basic information about the target, protein structure, biological mechanism of the target, drug resistance of the target, disease correlation, etc.
3) Analysis: Summarize long content, generate reports with one click, recommend target points, etc.
Target Prediction
Predicting targets that can successfully enter the clinical trial stage and ensuring that lead compounds based on predicted targets can successfully break through the PCC stage within an estimated time frame.
Target-based Drug Prediction
Predicting the difficulty level of target-based drug development provides a basis for assessing the value of target exploration.
Disease-Related Target Prediction
Predicting key targets for specific diseases and provide a basis for drug development for rare diseases and difficult and complicated diseases.
Common Targets and Diseases
Targets
ABCB1 | ABCG2 | ACE2 | AHR | AKT1 | ALK | AR | ATM | BAX | BCL2 | BCL2L1 | BECN1 | BRAF | BRCA1 | CAMP | CASP3 | CASP9 | CCL5 | CCND1 | CD274 | CD4 | CD8A | CDH1 | CDKN1A | CDKN2A | CREB1 | CXCL8 | CXCR4 | DNMT1 | EGF | EGFR | EP300 | ERBB2 | EREG | ESR1 | EZH2 | FN1 | FOXO3 | HDAC9 | HGF | HMGB1 | HSP90AA1 | HSPA4 | HSPA5 | IDO1 | IFNA1 | IGF1 | IGF1R | IL17A | IL6 | INS | JUN | KRAS | MAPK1 | MAPK14 | MAPK3 | MAPK8 | MAPT | MCL1 | MDM2 | MET | MMP9 | MTOR | MYC | NFE2L2 | NLRP3 | NOTCH1 | PARP1 | PCNA | PDCD1 | PLK1 | PRKAA1 | PRKAA2 | PTEN | PTGS2 | PTK2 | RELA | SIRT1 | SLTM | SMAD4 | SOD1 | SQSTM1 | SRC | STAT1 | STAT3 | STAT5A | TAK1 | TERT | TLR4 | TNF | TP53 | TXN | VEGFA | YAP1
Diseases
ACTH-independent Macronodular Adrenal Hyperplasia | Keratosis | Tay-Sachs Disease | Tuberculosis | Congenital Adrenal Hyperplasia | Desbuquois Syndrome | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Huntington's Disease | Guillain-Barre Syndrome | Oligoasthenoteratozoospermia | Wolff-Parkinson-White Syndrome | Prediabetes | Chitayat Syndrome | Silicosis | Hyperlipidemia Type V | Malignant Peripheral Nerve Sheath Tumor | Vitamin D Deficiency | Thrombophlebitis | ADNP Syndrome | Corneal Dystrophy And Perceptive Deafness | Epilepsy, Generalized | Lateral Meningocele Syndrome | Episodic Ataxia Type 2 | Familial Mediterranean Fever | Placenta Previa | Sorsby Fundus Dystrophy | Neuroblastoma | Fibromuscular Dysplasia | Encephalopathy, Hepatic | Periventricular Leukomalacia | LEOPARD Syndrome | Diverticulitis | Encephalopathy | Echinococcosis | Hereditary Folate Malabsorption | Duane Retraction Syndrome | Mitochondrial Myopathy | Metabolic Diseases | Renal Failure | Bacterial Meningitis | Dominant Optic Atrophy | Nicolaides-Baraitser Syndrome | Heimler Syndrome | Benign Familial Neonatal Convulsions | Idiopathic Multicentric Castleman Disease | Antithrombin III Deficiency | Protein C Deficiency | Iron Metabolism Disorders | Antley-Bixler Syndrome | Osteomyelitis | Genitopatellar Syndrome | Lamellar Ichthyosis | Nager Acrofacial Dysostosis | Common Cold | Carcinoma, Squamous Cell | Klippel-Feil Syndrome | Asplenia | Odonto-onycho-dermal Dysplasia | Hypothyroidism | Congenital Hereditary Endothelial Dystrophy Type I | Craniofacial Dysostosis | Ocular Albinism Type 1 | Liver Diseases | Trismus-pseudocamptodactyly Syndrome | Warsaw Breakage Syndrome | Sponastrime Dysplasia | Renal Tubular Acidosis | T-cell Prolymphocytic Leukemia | Leukodystrophies | Melanoma | Polymyositis | Thyroiditis | Rheumatoid Arthritis | Seborrheic Dermatitis | Scleroderma | Follicular Dendritic Cell Sarcoma | Congenital Absence Of Vas Deferens | Steel Syndrome | Majeed Syndrome | Intracerebral Hemorrhage | Ischemia | Triphalangeal Thumb-polysyndactyly Syndrome | Spinal Muscular Atrophy | Uremia | Cholangitis | Knobloch Syndrome | Porphyria, Variegate | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Gestational Trophoblastic Disease | Chronic Lymphocytic Leukemia | Pneumonia, Mycoplasma | Pendred Syndrome | Sarcoma, Ewing | Addison Disease | Borderline Personality Disorder | Vasculitis | Achondrogenesis | Esophageal Motility Disorders | Trichothiodystrophy | T-cell Leukemia | Pontocerebellar Hypoplasia | Wiskott-Aldrich Syndrome | Hyperbilirubinemia | Dentinogenesis Imperfecta | Fetal Akinesia Deformation Sequence | Rothmund-Thomson Syndrome | Keloid | Pregnancy, Ectopic | Fibrosarcoma | Rheumatic Heart Disease | Fuchs Dystrophy | Giant Cell Arteritis | Epidermolysis Bullosa Simplex, Generalized | Malignant Fibrous Histiocytoma | Liver Failure | Dysgerminoma | Blood Protein Disorders | Multifocal Motor Neuropathy | CEDNIK Syndrome | Unverricht-Lundborg Syndrome | Spinocerebellar Ataxia Type 21 | Periodic Limb Movement Disorder | Juvenile Hyaline Fibromatosis | Esophagitis | Osteonecrosis | Retinitis | Megalencephaly | Ophthalmia, Sympathetic | Muckle-Wells Syndrome | Microcephaly, Seizures, And Developmental Delay | Duchenne Muscular Dystrophy | Osteopetrosis | Meleda Disease | Pitt-Hopkins Syndrome | Hermansky-Pudlak Syndrome | Adenoma, Pleomorphic | Asperger Syndrome | Neurofibroma | PHARC Syndrome | Hemorrhage | Lipodystrophy | Pelvic Inflammatory Disease | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Ghosal Syndrome | Eccrine Porocarcinoma | Dental Caries | Polymyalgia Rheumatica | Distal Myopathy | Imerslund-Grasbeck Syndrome | Migraine | Still Disease | DRESS Syndrome | Chromosome 5q Deletion Syndrome | Colitis, Microscopic | Schizencephaly | Lymphedema-distichiasis Syndrome | Stargardt Disease | Eiken Syndrome | Pancreatitis | Cutis Laxa | Malonyl-CoA Decarboxylase Deficiency | Reflex Epilepsy | Persistent Fetal Circulation | Paraganglioma, Carotid Body | Sotos Syndrome | Polycythemia Vera | Spasticity | Pulmonary Stenosis | Schnitzler Syndrome | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Diabetes Type 1 | Hereditary Elliptocytosis | Osteogenesis Imperfecta Type IV | Mitochondrial Cytopathy | Focal Dermal Hypoplasia | Mood Disorder | Aarskog-Scott Syndrome | Anovulation | Hydrocephalus, Normal Pressure | Tardive Dyskinesia | Osteopathia Striata With Cranial Sclerosis | Tibial Muscular Dystrophy | Urticaria | Behcet's Disease | Panuveitis | Persistent Mullerian Duct Syndrome | Neurodermatitis | Oculopharyngeal Muscular Dystrophy | Granular Corneal Dystrophy | Cancer, Breast | Necrotizing Autoimmune Myopathy | Uveitis | Bronchitis, Chronic | C3 Glomerulopathy | Paraganglioma | GLUT1 Deficiency Syndrome | Microphthalmia | Niemann-Pick Disease, Type C | Tinea | Cancer, Bladder | Autonomic Neuropathy | Dementia | Metaphyseal Chondrodysplasia, Schmid Type | Gerodermia Osteodysplastica | GAPO Syndrome | Meningioma, Benign | Marinesco-Sjogren Syndrome | Chondroma | Spina Bifida | Pneumococcal Meningitis | Congenital Adrenal Hyperplasia 1 | Sialoadenitis | Microphthalmia, Syndromic 7 | Withdrawal Syndrome | Diabetic Nephropathy | Adenoma, Pituitary | Gastroschisis | Central Core Disease | Meningioma | Parapsoriasis | Spinocerebellar Ataxia Type 20 | Creatine Deficiency Syndrome | Primary Ovarian Insufficiency | Encephalitis, Tick-borne | Familial Episodic Pain Syndrome | Renal-hepatic-pancreatic Dysplasia | Genee-Wiedemann Syndrome | Tremor | Kearns-Sayre Syndrome | Geleophysic Dysplasia | Gastric Atrophy | Autosomal Recessive Bestrophinopathy | Skin Papilloma | Subacute Sclerosing Panencephalitis | Osteochondrosis | Atopic Dermatitis | Myoclonic Epilepsy With Ragged Red Fibers | Prolidase Deficiency | Peutz-Jeghers Syndrome | Androgenic Alopecia | Acute Leukemia | H Syndrome | MELAS Syndrome | Chylomicron Retention Disease | Carbonic Anhydrase VA Deficiency | Carpal Tunnel Syndrome | Aicardi-Goutieres Syndrome | Cranial Nerve Disease | Herpes Genitalis | Ependymoma | Myotonic Disorders | Myositis | Glomerulonephritis, Membranous | Hemorrhoids | Nail-Patella Syndrome | Stroke | Central Retinal Artery Occlusion | X-linked Creatine Transporter Deficiency | Cataract | Persistent Hyperplastic Primary Vitreous | Azoospermia | Vitamin B12 Deficiency | Congenital Fiber-type Disproportion Myopathy | Leiomyosarcoma | Angioedema | Impulse Control Disorder | Coronary Heart Disease | Lysosomal Acid Lipase Deficiency | Tenosynovial Giant Cell Tumor | Tietze Syndrome | Maple Syrup Urine Disease | Diffuse Intrinsic Pontine Glioma | Diabetes Mellitus, Transient Neonatal | Anorectal Malformations | Hepatopulmonary Syndrome | Leigh Syndrome | Wolman Disease | Cabezas Syndrome | Peroxisomal Disorder | Dowling-Degos Disease | Mitochondrial Disease | Pulmonary Tuberculosis | Epidermolysis Bullosa Simplex | Olmsted Syndrome | Primary Progressive Nonfluent Aphasia | IgA Nephropathy | Brugada Syndrome 1 | Hypertension, Renal | Gangliosidosis, GM1 | Venous Insufficiency | Sarcoidosis, Pulmonary | Zellweger Syndrome | Charcot-Marie-Tooth Disease Type 4E | Keratosis, Actinic | Conduct Disorder | Trachoma | Leri-Weill Dyschondrosteosis | Hyperoxaluria | Meningococcal Infections | Essential Fructosuria | Epidermal Nevus Syndrome | Hepatitis B, Chronic | Heterotopic Ossification | IgA Deficiency | Retinitis Pigmentosa 3 | Prurigo Nodularis | Cyst | Hyperphenylalaninemia | Malaria, Cerebral | Optic Atrophy 2 | Poirier-Bienvenu Neurodevelopmental Syndrome | Carcinoid Tumor | Tyrosinemia Type 2 | Primary Aldosteronism | Leukemia-lymphoma, Adult T-cell | Congenital Tufting Enteropathy | Personality Disorders | Iron Overload | Combined Deficiency Of Factor V And Factor VIII | Hypoalbuminemia | Cancer, Lung | Ganglioglioma | Ureteropelvic Junction Obstruction | Cat Eye Syndrome | Methylmalonic Aciduria And Homocystinuria, CblC Type | Vascular Cognitive Impairment | Orthostatic Intolerance | Congenital Sodium Diarrhea | Speech Disorders | Esophagitis, Eosinophilic | Congenital Myopathy | Osteoporosis, Postmenopausal | Granuloma Annulare | DNA Ligase IV Deficiency | Perry Syndrome | Hypersensitivity | Familial Partial Lipodystrophy | Erectile Dysfunction | Adenosine Deaminase 2 Deficiency | Cockayne Syndrome | Multiple Sclerosis | Von Willebrand Disease | Pneumonia, Viral | Retinoschisis | Craniopharyngioma | Esthesioneuroblastoma | Galloway-Mowat Syndrome | Hypohidrotic Ectodermal Dysplasia, X-linked | Trichuriasis | Gnathodiaphyseal Dysplasia | Turner's Syndrome | Paraplegia | Richter's Syndrome | Kaposi Sarcoma | Mycosis Fungoides | Sialidosis Type I | Osteogenesis Imperfecta Type I | 3-methylglutaconic Aciduria Type I | Glioblastoma Multiforme | Lymphomatoid Granulomatosis | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Purpura, Thrombotic Thrombocytopenic | Chronic Kidney Disease | Globozoospermia | Bainbridge-Ropers Syndrome | Ectopia Lentis, Isolated, Autosomal Recessive | Osteoporosis | Cholesteryl Ester Storage Disease | Heterotaxy | Meningeal Melanocytoma | Dysequilibrium Syndrome | Macular Degeneration | Distal Spinal Muscular Atrophy | Myelomeningocele | Stuve-Wiedemann Syndrome | Klinefelter Syndrome | Trichomegaly | Usher Syndrome | Heavy Chain Disease | Argininosuccinic Aciduria | C3 Glomerulonephritis | Hennekam Lymphangiectasia-lymphedema Syndrome | Diabetes Insipidus, Nephrogenic | Dermatitis | Vitreoretinopathy, Proliferative | Joubert Syndrome 2 | Hereditary Coproporphyria | Autonomic Nervous System Disorders | Epidermolysis Bullosa Acquisita | Goiter | Optic Nerve Diseases | Urethritis | Craniometaphyseal Dysplasia | Cri-du-chat Syndrome | Binge Eating Disorder | Enlarged Vestibular Aqueduct | Syndactyly | Schizophrenia | Common Variable Immunodeficiency | Trigonocephaly
