哮喘

疾病概述
哮喘，也称为慢性阻塞性哮喘，与过敏性哮喘和儿童期发病的哮喘有关，其症状包括反复出现喘息、胸闷和气短等症状。与哮喘相关的一个重要基因是 IL13（白细胞介素 13），其相关途径/超级途径包括同种异体移植物排斥以及白细胞介素 4 和白细胞介素 13 信号传导。在这种疾病的背景下提到了芬太尼和依托咪酯药物。附属组织包括肺、平滑肌和皮肤，相关表型有哮喘和支气管收缩

主要靶点
PPARA | CSK | F2RL1 | TMEM132E | ADK | ITPR2 | TEC | VWF | CACNA2D1 | KLF13 | PNMT | CCR10 | CCL26 | ACTR3B | CSMD3 | Prostanoid Receptor (nonspecified subtype) | Tyrosine-Protein Kinases Src (nonspecified subtype) | LPL | ZBTB38 | LINC00536 | PTGES | G3320 | Interferon-alpha (IFN-alpha) (nonspecified subtype) | CSF3 | SLC6A7 | AP2A2 | D2HGDH | PADI4 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | Integrin alphaMbeta2 (MAC-1) Receptor | KCNA3 | Protein kinase C (nonspecified subtype) | ZFPM1 | MED23 | PSMB5 | CYSLTR1 | CLEC7A | NUCKS1 | DUSP3 | MRPL4 | G2475 | cAMP Phosphodiesterase (nonspecified subtype) | L-type voltage-dependent calcium channel complex | IL-15 receptor | PDGFRB | RETREG1 | LOC101927770 | RFPL3S | Protein Kinase B (PKB/Akt) (nonspecified subtype) | CCN1 | IKBKB | ADAMTS14 | ADRA1A | C-C chemokine receptor (nonspecified subtype) | Calcium channel (nonspecified subtype) | MIR6884 | CD247 | LOC107986606 | IL2RA | KCNN3 | UMODL1 | FADS2 | COLEC10 | PTPRD | RAC1 | MYLK4 | TRPM8 | CRELD2 | TLR10 | IL23A | NAP1L5 | SCEL | CARM1 | ST13 | TOP1 | ARID1B | AP1S3 | IL13RA1 | SLC18A2 | P2RX1 | TAC4 | GABRA4 | KIAA1549L | GAPDH | TNFSF14 | LINC00824 | PRMT6 | MKNK2 | CD6 | RPS6KA2 | KRT25 | ADAD2 | NGFR | SSBP3 | PDE8A | AXL | DNAI2 | GARS1-DT | TNFRSF25 | CYP3A7-CYP3A51P | HLA-DQA1 | PHACTR2 | POLI | KRT27 | CCR6 | C5 | RBFOX1 | ZNF841 | LMAN2 | IFNA13 | G59272 | KRT10-AS1 | Chemokine CXC receptor (nonspecified subtype) | NR1H2 | FKBP1A | Nuclear factor of activated T-cells (nonspecified subtype) | FAM78B | ESR2 | FGFR3 | KRBOX1 | PPARG | IKZF4 | ITPR3 | G1950 | NOS1 | TMEM9 | BPIFC | GRB10 | CHRM4 | SLC25A25 | Serine/Threonine Kinase (nonspecified subtype) | ST14 | THRB | FKBP4 | ORAI1 | IZUMO2 | Ribonucleoside-diphosphate reductase | DRD4 | MAOA | EPHX2 | ALOX5AP | GRIK1 | HTR1A | PTPRS | CNR1 | BRINP1 | SERPINA6 | LOC105375381 | Tachykinin Receptor (nonspecified subtype) | G1432 | CCBE1 | THSD4 | IL17RA | TBC1D29P | PIK3CD | MIR1268A | ORMDL2 | ADGRG1 | UNCX | IRF1 | Alpha-2 Adrenergic receptors (nonspecified subtype) | ANXA2R | STAT6 | TYR | PLA2G4A | POU2F1 | DCAF15 | MED17 | CGREF1 | LOC107986774 | STIP1 | SCGB1A1 | SBNO2 | TAS2R14 | SLC24A2 | TIMD4 | ROCK1 | SLC6A2 | LTA | LPAR1 | FLG | CTNNA3 | HHAT | PTGER3 | IFNGR1 | NACC2 | SGCG | G7295 | TRPV1 | BRD4 | PRMT8 | LRBA | Lipoxygenase (nonspecified subtype) | ABTB3 | IKZF5 | ALDH2 | G7852 | P2RY2 | RUNX3 | LINC01425 | LOC101928940 | Phosphodiesterase 1 (PDE1) (nonspecified subtype) | Cyclophilins (nonspecified subtype) | OXA1L | TMEM272 | Uncharacterized LOC101928947 | PRKCA | GSTM4 | MED27 | G142 | NFATC1 | YWHAB | DDR2 | KLK5 | NR3C1 | AURKB | SPHK2 | FMNL2 | CPS1 | AKR1C2 | TAC3 | TCF12 | MMP3 | EVI5 | PRDM16 | JAKMIP1 | LCK | TRAF3 | ITSN2 | IKZF1 | ADIPOQ | MGLL | I-kappa-B-kinase (IKK) complex | MYL6B | TMBIM6 | MPST | FAM13C | OPN3 | CHRM1 | IRX2 | CTSF | IFNL3 | PTGIR | LOC349160 | IL4R | SELL | Estrogen receptor (nonspecified subtype) | NPSR1 | HDAC1 | PMEPA1 | PSMD3 | CTSS | MAP3K5 | PAX2 | CASR | SNRK | RPS6KA3 | ZNF80 | NPY1R | PTGS1 | KCNQ3 | BTNL9 | DHODH | GABRG2 | ABI3BP | PIK3CB | SLC16A7 | PRSS8 | CLSTN2 | MITF | SERPINB10 | PMS1 | NPC1L1 | MMP24 | HMGCR | KEAP1 | NLRP8 | G6352 | NKX2-1 | ALOX12 | ICAM1 | BRD2 | BMX | Phospholipase A2 (nonspecified subtype) | IPCEF1 | PPP3R2 | HMOX2 | C-X-C Chemokine Receptor CXCR1/CXCR2 (IL-8 Receptor) (nonspecified subtype) | Matrix Metalloproteinase (MMP) (nonspecified subtype) | Calcium release-activated channel (CRAC) | G2099 | ZFYVE26 | MZB1 | PGR | NOD1 | LINC00299 | CCR4 | ADORA1 | GABA(A) receptor | ARRB2 | OAS2 | G23411 | CDK5 | SCNN1A | APLNR | PAMR1 | LINC02116 | COL4A1 | IL10RA | TFAMP1 | PSMG3-AS1 | PARD3B | Chymotrypsin (nonspecified subtype) | BCR | BCAN | DMRT1 | ACHE | MAP3K20 | SIGLEC8 | HLA-A | ATP Synthase, H+ Transporting, Mitochondrial F0 complex | CCDC171 | ABCB4 | NR1H3 | HTR2B | NOD2 | HTR4 | DDIT4L | IL-1 Receptor (nonspecified subtype) | CYP1A1 | SYNPO2 | CDKAL1 | MAPK11 | SEMA3E | ADCY3 | ATP2C2 | PTPRE | IGHE | Integrin alpha4beta7 (LPAM-1) receptor | MMP12 | FZD3 | PDE10A | Steroid 5-alpha-Reductase (nonspecified subtype) | SPNS2 | ADORA2B | P2RX3 | NEDD4L | PIK3CA | MIR3162 | G5743 | Voltage-Gated Sodium Channel Complex | AQP4-AS1 | TRPV2 | G3BP1 | ANO1 | PPP3CC | Endogenous retrovirus group K member 25 Pol protein-like, transcript variant X1 | CTSL | LRP5 | ASAH1 | FPR1 | TNS4 | GLI3 | LOC105373608 | LOC105375670 | ZNF287 | HSD11B1 | SLC22A12 | CSNK1A1L | CNTNAP5 | SHANK2 | HDAC3 | G999 | Integrin Receptor (nonspecified subtype) | GMIP | HDAC7 | TNFRSF18 | CD14 | ANXA2R-AS1 | HMGA2 | HLA-G | IRAK3 | Protein Tyrosine Phosphatase (PTP) (nonspecified subtype) | GRK3 | SNRPD1 | F3 | ACIN1 | PCDH1 | GSTA1 | IL3 | IL7R | IRF3 | Tubulin | ADAM17 | RPUSD2 | GNG4 | ADP-Ribosyl Cyclase/cyclic ADP-Ribose Hydrolase (ADPRC) (nonspecified subtype) | LPP | ETV6 | TBX21 | BTNL2 | CHIT1 | XIAP | Small Conductance Calcium-Activated Potassium Channel (SK) (nonspecified subtype) | APCDD1 | MTHFR | SPSB1 | MKNK1 | PDCD4 | HSPA12B | AP3S1 | SLC26A3 | HDAC5 | PEX11B | LINC01149 | FER | NOTCH4 | G5243 | GNAQ | CNOT7 | CD44 | ICAM4 | CCN2 | SYK | TAFA1 | CCR2 | NOX4 | LINC01730 | UBE3C | HNRNPH1 | ADORA2A | ARG1 | MTRR | LOC101060445 | TNFSF13B | PITHD1 | G3630 | Acetylcholine Receptors (Nicotinic) (nAChR) (nonspecified subtype) | ABCA1 | VIP | TMBIM4 | NR1I2 | CDK9 | LTB4R2 | Neurotrophic Factor (nonspecified subtype) | IL12RB1 | CFAP54 | KCNN4 | DPP4 | PPARD | MAP3K14 | GRIN2D | IL1RL1 | GRM2 | PGAP3 | EIF2AK2 | CXCR1 | TGFBR1 | F2 | JMJD1C | CD40 | IL-2 receptor | CSTA | PRSS35 | MAP3K11 | NTRK1 | AKR1B1 | PPP1R1B | PRORP | ALOXE3 | Tyrosine Kinase (nonspecified subtype) | G3605 | G4318 | CEP44 | S1PR4 | ATG5 | CHRNA7 | G1956 | NTRK3 | TUBGCP3 | CLC | PYHIN1 | CCDC88C | ARPC2 | CHFR | S1PR2 | LOC105371081 | ATP5IF1 | IL-4 receptor | Phospholipase C (nonspecified subtype) | Sodium channel (nonspecified subtype) | XDH | DCAF4 | RNF220 | GSTT1 | NFKBIA | ALPK1 | EEFSEC | KITLG | RERE | URAHP | NR4A1 | PTPN1 | CYP11A1 | MIR141 | ARRB1 | G4233 | SLFN12L | DLC1 | SHROOM3 | SAMD5 | Alcohol Dehydrogenase (nonspecified subtype) | TMEM196 | GSDMA | LINC00663 | LOC101928004 | BCHE | Gap junction Connexin ( (nonspecified subtype) | VPS37A | GFRA4 | EVC | VDR | GNL1 | PDZRN4 | CD38 | PGAM5-KEAP1-NRF2 Complex | Chloride channel (nonspecified subtype) | ZNF614 | Guanylate cyclase (nonspecified subtype) | MED12L | MAPK12 | TLR2 | PBX1 | GSK3B | HDC | FBXL14 | KTN1 | TGM2 | SERPINC1 | NPY2R | P2RY6 | SYN3 | RHCG | CHCHD6 | G367 | MICB | VCAM1 | XPO1 | PPP2R2B | G5595 | SFRP4 | ZBTB39 | REL | SELP | INSR | ITGB2 | EDNRB | FCGR3A | TLE6 | DZANK1 | NRM | G3480 | G4137 | GPR4 | ATP6V1G1 | IL15 | PDS5B | SERPINE1 | IRAK4 | ILDR1 | GIMAP4 | HLA-DRA | ATXN7L1 | DPP7 | NR1H4 | Adenylate Cyclase (nonspecified subtype) | GGCT | TRAPPC9 | ABT1 | Calcium-Activated K(Ca) Potassium Channel (nonspecified subtype) | IRF4 | Integrin alpha5beta1 (VLA-5) receptor | ARID4B | HAL | Epithelial Sodium Channel (ENaC) | TK1 | ZFHX3 | Phosphatidylinositol 4-Kinase beta (PI4K-beta) (nonspecified subtype) | ITK | SFTPC | TTK | NOS3 | DNAJC14 | FLVCR1 | TMPRSS11D | PARP11 | Interleukin-12 (IL-12) | CTSG | CFAP53 | ATP1B2 | CFHR5 | MKS1 | XPR1 | CES1 | CHRNA2 | IL10 | G2064 | IQSEC1 | NEK7 | DLG2 | ALCAM | XRCC3 | MEX3B | SULT1B1 | PSMA6 | IL-5 receptor | LARP4 | H2BC26 | OPRD1 | DICER1 | FBXL20 | UTS2R | DPP8 | G581 | CDHR3 | CLEC2D | ARAP2 | IL-20 receptor | KDR | Mitogen-Activated Protein Kinase (nonspecified subtype) | S1PR3 | PDPK1 | DLEU1 | AGPAT1 | Neurotrophic Tyrosine Kinase Receptor (TRK) (nonspecified subtype) | DAD1 | ZAP70 | TBL1XR1 | C7orf50 | MAPKAPK2 | PRMT1 | ITGA4 | FKBP5 | FCRL3 | RORA | SLC16A1 | FREM1 | SSTR4 | EPHA3 | ZNF154 | FOXM1 | PALM | SETBP1 | GRIN2A | HLA-DPA1 | CHRM3 | IL9 | cAMP-Dependent protein kinase (PKA) | SLC22A2 | PXDN | DHX58 | FCMR | C6orf118 | TBP | ZNF311 | PTGER4 | Platelet-Derived Growth Factor Receptor (nonspecified subtype) | STAT5 (nonspecified subtype) | ADORA3 | MMP7 | TPSAB1 | PLG | TSLP | LINC02006 | Interferon (nonspecified subtype) | MIR328 | TET1 | GIMAP1-GIMAP5 | ZNF652-AS1 | POU6F2 | Inhibitory kappaB Kinase (IKK) (nonspecified subtype) | PLPPR5 | PIKFYVE | MMP2 | SPATA13 | MAP1LC3B | NYAP2 | RTN1 | ZBTB7C | G2309 | ABCB9 | LINC02037 | MAPK9 | ERN2 | CCL11 | C3AR1 | PPP1R12B | RAPGEF4 | CXCL12 | NCK1 | NPY | MROH7-TTC4 | LINC02556 | K(ATP) Channel (nonspecified subtype) | Arrestin (nonspecified subtype) | TPT1 | TRPC6 | RIOX2 | ACP5 | GLCCI1 | 15-Lipoxygenase (nonspecified subtype) | Pim Kinase (nonspecified subtype) | DENND1B | TIE1 | PTGDR | RHOBTB1 | BACH2 | CTLA4 | DEFA1 | TEK | P2RX4 | MAP3K19 | EVL | SMYD2 | SMURF1 | IL1B | CDH22 | MAVS | CYP3A5 | FLT3 | CTSA | RAD50 | NSMCE2 | MIB1 | RAF1 | LOC101928180 | PRKCD | SLC12A7 | PTGDR2 | PTPRK | Heme Oxygenase (HO) (nonspecified subtype) | G3569 | IL-6 receptor | KLC1 | STAT4 | LSP1 | G920 | PSMB1 | KRT10 | TMEM221 | PDE5A | UBAC2 | RARB | CCR8 | IL1R1 | Interferon alpha/beta Receptor (nonspecified subtype) | G7422 | CXCR3 | FOXN3 | TMEM106A | JKAMP | LINC02885 | MARCHF9 | ADRB1 | IgE Receptors (nonspecified subtype) | FAAH | MPIG6B | NRP1 | QPCTL | GSDMB | HSPA8 | GSTO2 | CYP2R1 | IL2 | IL5 | Trypsin (nonspecified subtype) | Nucleoside Diphosphate Kinase (NDK) (nonspecified subtype) | Glycogen synthase kinase 3 (GSK-3) (nonspecified subtype) | MX1 | NAB2 | JAZF1 | CEP131 | UBR2 | AKAP1 | LRCOL1 | ANXA2P2 | POSTN | Phospholipase A2, Cytosolic (nonspecified subtype) | GIMAP1 | UNC13C | ALDH1A1 | FASN | GABRP | DDIT4 | ANO2 | CYP4F8 | Elastase (nonspecified subtype) | IL1A | CYP3A7 | MBL2 | ARHGEF3 | QPCT | MICU3 | HTR2A | BCL2A1 | beta-Adrenoceptor (nonspecified subtype) | RTEL1 | GRM8 | PDE4DIP | ABCC8 | MAPK8IP3 | CYFIP1 | SARNP | RAB11FIP4 | SLC26A11 | RPP25 | OSBPL5 | KLK1 | MAP3K7 | GPR84 | ACBD5 | SEC24A | TMEM63C | CD70 | TPH2 | EYS | P2RY12 | FLG2 | FDPS | ZFYVE1 | TLR9 | TTC34 | Serine protease (nonspecified subtype) | PKD1L1 | Toll-Like Receptor (nonspecified subtype) | OTULINL | LHX5 | Prostanoid TP receptor (nonspecified subtype) | ZBTB49 | PSORS1C1 | KDM1A | CHIA | CALCRL | GRID1 | SIRPB1 | RNF14 | SIGLEC1 | LRRC27 | ANO10 | IL17F | Cysteine Protease (nonspecified subtype) | LYPD4 | NRROS | LIPC | NOS2 | BDNF-AS | COMMD10 | SNX9 | PFKP | LGR5 | LOC100129603 | TRPA1 | CYLD-AS1 | CHUK | IFNG | NMDA receptor | VIPR2 | TNFRSF11A | SLC19A2 | CCNI | DDR1 | LOC105378206 | AP-1 Transcription Factor Complex | IRF5 | Triacylglycerol Lipase (TG Lipase) (nonspecified subtype) | TIMP1 | AGPAT4 | LTBP1 | MMP13 | EPX | NPB | RGS5 | LYAR | NRXN1 | CRHR1 | Immunoglobulin E (IgE) | CD1D | TIGAR | HRH1 | FASLG | NTSR1 | PDGFRA | CRCT1 | GSTP1 | SCN9A | IGFBP-AS1 | MALAT1 | PDE2A | PDE6D | KLF7 | CFTR | SORCS2 | RXRA | High Affinity Immunoglobulin Epsilon Fc Receptor | KIFC3 | TBX5 | ZFP37 | PDE1B | NDE1 | PIAS3 | CTSC | LOC107984238 | AOX1 | NUAK1 | CSF2 | PTTG1IP | PDE3B | ZNF414 | SLC9C2 | PRKCB | ROCK2 | CCR9 | Integrin alphaLbeta2 (LFA-1) receptor | G196 | TMEM126A | SGSH | KIF11 | SPTBN1 | IKZF3 | ICOSLG | LINC01276 | OSBPL10 | CCR1 | CXCR2 | TMPRSS9 | JAK2 | CYP2C9 | TACR1 | AGTR1 | ARHGAP10 | NOX3 | HMMR | SFTPD | L-Type calcium channel (nonspecified subtype) | ADRB2 | FBXL7 | FPR2 | NUPR1 | TREM1 | LOC105369749 | LOC105371770 | LOC105376253 | ZNF423 | ADCYAP1R1 | BMPER | Janus Kinase (nonspecified subtype) | TNS1 | TPH1 | GAA | GRM8-AS1 | LOC105371775 | LOC107984326 | Complement Complex | TXNRD1 | ZNF365 | BRPF1 | ADAM12 | PDCD4-AS1 | LOC105371776 | MAP2K2 | OGA | Leukotriene B4 receptor (LTB4-R) (nonspecified subtype) | WT1 | MIR499B | CHI3L1 | CCL17 | STAB1 | HSD11B2 | CCR5 | SDK2 | LOC101929563 | Tryptase (nonspecified subtype) | RORB | Muscarinic Acetylcholine Receptor (mAChR) (nonspecified subtype) | LDHA | MYLK | VHL | MICB-DT | ST8SIA5 | NPS | Proteasome Complex | IL25 | SLC22A4 | LYN | PON1 | LINC01317 | GSTM1 | PTPRN2 | RPTN | COL26A1 | Integrin alphavbeta6 receptor | 5-Hydroxytryptamine Receptor 2 (5-HT2) (nonspecified subtype) | FCGR2A | ZNF665 | GC | GCLM | C1QTNF3 | RNASE2 | JAK3 | TYMS | S1PR5 | BDKRB1 | IL12A | CREBBP | IFIH1 | JAK1 | NF-kappaB (NFkB) | Histone deacetylase (nonspecified subtype) | MIR146A | DENND1C | OTOGL | HOXB5 | OXER1 | CLEC16A | COG6 | LOXHD1 | alpha1-Adrenoceptor (nonspecified subtype) | Gastric H+/K+-ATPase | GABRA5 | MRI1 | IQCJ-SCHIP1 | LOC105374553 | IL5RA | DPP6 | LINC00426 | SC5D | TACO1 | LOC105374591 | DCTN1-AS1 | CNKSR1 | PPP3CB | NLRP3 Inflammasome | AQP5 | ITGB3 | SPI1 | PIN1 | GGT1 | ZMIZ1-AS1 | TNK2 | HLA-DPB1 | ADH5 | G3576 | beta-Hexosaminidase Complex | KCNMA1 | TMEM30B | TLL1 | ACO1 | IL1RL2 | NAMPT | C5orf64 | PTPN4 | IL4 | Adenosine receptor (nonspecified subtype) | CACNA1A | PDE11A | SERPINA1 | SPHK1 | IFNAR1 | MIF | ERN1 | HAVCR2 | PARP2 | NUDCD2 | F11 | TNFRSF4 | FBLN2 | NQO2 | CRISPLD2 | PPP3R1 | CHRM5 | HTR2C | NPSR1-AS1 | PDCD1LG2 | TAOK3 | ARPC1B | G114548 | TIGIT | TOP2A | C3 | NRAP | CRBN | ABR | MAPK10 | PTGER1 | STING1 | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 (nonspecified protein) | GALNT18 | AGER | DRD3 | TNFRSF10D | AIRE | NADPH Oxidase Complex | SHH | CTSK | G472 | NT5E | PRR5L | PDE4A | PRKCQ | LINC02373 | NFAT5 | AKR1B10 | PVR | SMAD3 | ASIC1 | C5AR1 | MUC4 | PPP6R3 | LINC02220 | CYSLTR2 | CD300A | CRYBA4 | TPSB2 | ALB | NAP1L4 | P2RX2 | ALOX5 | POLA1 | CCDC146 | Adrenoceptor (nonspecified subtype) | TBX15 | MMP8 | TNXB | DCDC2 | PLA2G2D | LOC105378617 | HLA-C | HLA-DQB1 | Inositol 1,4,5-Trisphosphate Receptor (InsP3R) (nonspecified subtype) | KIFC1 | GARIN1B | SERPINB7 | TNFSF15 | KRT28 | ZNF224 | SEMA3B | ICMT | GATA3 | GLB1 | SLC30A9 | SCHIP1 | SAFB2 | G3146 | Nitric oxide synthase (NOS) (nonspecified subtype) | IL6R | IL13 | ABCC1 | NLRP1 | P2RX7 | CASP1 | TAGLN2 | COG8 | TCAP | Large Conductance BK(Ca) Potassium Channel (Maxi K+ Channel) (nonspecified subtype) | SCGB3A2 | CCL2 | SORD | LINC02882 | Calcium-activated chloride channel regulators (nonspecified subtype) | CRYBB1 | TMEM267 | CYP27A1 | CRB1 | FYN | RGMB | PIWIL1 | CD28 | Phospholipase A2, Secretory (sPLA2) (nonspecified subtype) | Focal Adhesion Kinases (FAK) (nonspecified subtype) | TAMALIN | LOC100507389 | MAGI1 | HSPA1B | COL4A3 | NLRP4 | LRP1B | ZNF432 | NECTIN1 | Gap Junction Protein (nonspecified subtype) | KRT74 | 5-Hydroxytryptamine Receptor (nonspecified subtype) | RXRB | MROH7 | SLC7A2 | G6PD | SPATS2L | LINC02752 | P2RY14 | Histamine Receptor (HR) (nonspecified subtype) | CTSB | F2R | NPR1 | PLA2G7 | CLDND2 | Chemokine receptor (nonspecified subtype) | CRLF2 | G7124 | MKNK1-AS1 | GLP1R | BCAS3 | IFITM3 | ZNF684 | Integrin alphavbeta1 | SLC6A3 | Potassium Channels (nonspecified subtype) | LDHB | DHFR | KRT24 | CMKLR1 | Arginase (nonspecified subtype) | LIPE | SLMAP | PARP8 | ORMDL1 | CD63 | KRR1 | HSD17B1 | KCNMB1 | KIT | SLC22A5 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | NELL1 | GPC6 | GPR55 | NR1D1 | Retinoid RXR receptor (nonspecified subtype) | RPLP0 | IRAK1 | ZNF542P | LINC03033 | CACNA1E | DNAAF9 | MED1 | CFAP46 | PPP1R3F | TLR6 | ITPKA | DGKI | LOC107984932 | cGMP-inhibited 3',5'-cyclic phosphodiesterase 3 (PDE3) (nonspecified subtype) | ACAT2 | TLR7 | ASB2 | IL18R1 | TNIP1 | MPPED2-AS1 | ORMDL3 | IL22RA2 | TGFB1 | PIK3CG | LOC101928387 | MRGPRX2 | RPN1 | TPRA1 | Endothelin receptor (nonspecified subtype) | RND3 | MAOB | TNFRSF1A | SPDEF | LRRC3C | LTC4S | USP49 | ZNF385A | ACP4 | KIF3A | LRRC4C | RAB5B | MIR196A2 | IPO13 | NADPH Oxidase (nonspecified subtype) | PPARGC1B | IL20 | ABL1 | ABLIM2 | SFXN4 | ROBO1 | COL2A1 | LINC02694 | TBXA2R | RIPK1 | APLN | HMOX1 | Fibroblast Growth Factor Receptor (FGFR) (nonspecified subtype) | STX3 | TLN1 | UTP4 | KSR1 | FAM181A | TEX2 | FLG-AS1 | ARHGAP42 | SRFBP1 | Rho kinase (ROCK) (nonspecified subtype) | S1PR1 | ATRN | ATR | G5133 | SLC26A4 | SUSD6 | HSPA1L | SCN5A | IL-13 receptor | alpha-Amylase (nonspecified subtype) | PLEKHG4B | LTA4H | ACOT7 | Soluble guanylyl cyclase | TSHZ2 | RXRG | IL18 | IL1R2 | LACRT | MAPK13 | Integrin alphavbeta8 Receptor | INPP4A | GLT1D1 | FABP4 | MUC5AC | NLRX1 | ZNF30 | CSGALNACT2 | G7099 | PLCB1 | NDUFA6-DT | GRPR | KCNN1 | Dual Specificity Mitogen-Activated Protein Kinase Kinase (MEK) (nonspecified subtype) | SLC30A8 | TGFBR2 | HSPBP1 | GATM | CHRM2 | KCNJ10 | MMP1 | NDFIP1 | TMCO6 | ATPAF2 | LOC105372521 | CD151 | RPS5 | G673 | G6774 | G7157 | CD276 | HRH4 | Mitogen-activated protein kinase (JNK) (nonspecified subtype) | RTCB | CDK12 | G5347 | PRKCE | TRAF3IP2 | RGS2 | CSF2RB | CYP27B1 | SOX11 | PI3 | MAML3 | KIF16B | FCER1A | HPGDS | Collagenase (nonspecified subtype) | NTRK2 | KIRREL1 | DPP9 | LOC105370073 | PTAFR | Gamma-glutamyl transferase (nonspecified subtype) | PDE4D | LOC105370108 | PPARGC1A | Integrin alpha2beta1 (VLA-2) receptor | Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype) | ODC1 | AOC3 | CDK7 | PRKG1 | PTGFR | TAAR1 | CRHR2 | VSIR | TEAD1 | FOXP3 | GPR65 | ERP44 | PRR5 | RELN | G6647 | THRA | MPO | LOC105372630 | MIR3142HG | MED24 | ADCY9 | Superoxide dismutase (SOD) (nonspecified subtype) | TBXT | TRPC2 | NFKB1 | PTGER2 | CDH23 | PLAUR | AURKA | TXK | LOC101928516 | GPR182 | CMA1 | ZPBP2 | CCL25 | ARG2 | G6714 | BTK | TLR1 | MUC6 | NGF | PRRC2A | DNAJC5 | MRPL28 | COL11A2 | TNFRSF13B | MIR499A | Phosphodiesterase (nonspecified subtype) | HDAC6 | DLGAP2 | CACNA2D3 | NMUR2 | RORC | SLC38A6 | ALOX15 | HSD17B3 | AMP-activated protein kinase (AMPK) | WDR20 | LIPG | ARHGAP22 | DNA-Dependent Protein Kinase (DNA-PK) | SLC8A1 | TMEM150C | PDE3A | CLOCK | RAD51B | RGS3 | IL2RB | Bradykinin receptor (nonspecified subtype) | SLIT3 | LTF | SLC5A9 | GIMAP5 | LTB4R | CYP3A4 | PHF24 | TLR8 | POU4F3 | RTEL1-TNFRSF6B | CAMK1D | Glutathione peroxidase (nonspecified subtype) | G3620 | Interleukin-7 receptor | EDNRA | UBR1 | ADAM33 | ENPP2 | IL17RB | LOC107986139 | COL22A1 | SARDH | TIMP3 | PDE7A | IRAG1 | SELE | TRPM3 | NAALADL2 | MDGA1 | CHRNA5 | IL12B | INPP5D | LINC01973 | OPRM1 | PODXL2 | ONECUT1 | HRH3 | BDNF | TBXAS1 | GLCCI1-DT | HDAC2 | Protein Phosphatase 2B | CERK | Phosphodiesterase IV (PDE4) (nonspecified subtype) | NALF1 | MS4A2 | XBP1 | PGM1 | CAT | ITGAM | Monoamine oxidase (MAO) (nonspecified subtype) | LINC00032 | NTF3 | RIGI | TSPAN18 | ZBTB22 | ADCK5 | SEC31A | RIPK2 | IL1RN | RPS6KA1 | SNCA | ELANE | ZNF292 | Vasoactive intestinal polypeptide receptor (VIP-R) (nonspecified subtype) | ROBO3 | OTUD7A | HCK | HLA-DRB1 | DMRTC2 | TNFSF4 | FCER1G | YES1 | LPIN1 | PLA2G2A | CR2 | CSF1R | 5-Hydroxytryptamine Receptor 3 (5-HT3 receptor) (nonspecified subtype) | ACE | TACR3 | RAB29 | CFAP20DC-DT | TLR3 | OPRK1 | ENC1 | CNR2 | PLEKHH2 | GPBAR1 | Interleukin 17 (nonspecified subtype) | CDK2 | IRF1-AS1 | RPTOR | KCNIP4 | AP5B1 | METTL1 | G4780 | KMO | ESPNP | ZBTB48 | HLA-B | ICA1 | CCR3 | BDKRB2 | LHPP | IL33 | TAPBP | GPR35 | CD36 | Na+/H+ Exchanger (NHE) (nonspecified subtype) | PVT1 | LRRK2 | HAPLN1 | KCNH2 | FCER2 | CHST11 | PDE4B | GDNF | CACNA1H | ADAM10 | FFAR4 | ATP synthase, H+ transporting, mitochondrial F1 complex | FCGR2B | SIGLEC12 | G5599 | STARD3 | DGKQ | MIR149 | SIRT2 | TNFRSF11B | SEPTIN8 | NCOA3 | CBX4 | ACTA2 | ATL2 | CXCR5 | Interleukin-1 receptor-associated kinase (IRAK) (nonspecified subtype) | TSC1 | FGR | DLEC1 | CFB | TACR2 | MYO1F | CNTN5 | RUNX2 | XIRP2 | Heat shock protein 90 (nonspecified subtype) | CD3 Complex (T Cell Receptor Complex) | HCG18 | MPPED1 | PREP | PROC | HLA-DQB1-AS1 | Integrin alphavbeta3 (vitronectin) receptor | Integrin alpha4beta1 (VLA-4) receptor | NR3C2 | NPR3 | TNFAIP8 | UNK | CEBPE | MALT1 | DNASE1 | DRD2 | MFAP1 | NELL2 | INSL6 | P2X2/3 Receptor Complex | ITGB8 | TNFRSF1B | TYK2 | FCN2 | ZNF33A

《哮喘疾病靶点研报》是利用AI技术对数百至数万篇相关科研文献进行综合分析，并经过专业人员严格审核后提供的可订制化的专业研究报告，报告涵盖与哮喘相关的指定靶点或生物标志物特定信息，包括但不限于以下内容：
•   靶点/生物标志物基本信息；
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•   成药性;
•   相关联合用药;
•   药化试验;
•   相关专利分析;
•   靶点开发优势与风险...
研究报告有助于课题/项目申请、药物分子设计、研究进展汇报、研究论文发表、专利申请等。如果您希望获得该报告的完整版，请与我们联系： BD@silexon.ai

其它疾病

夜间哮喘 | 唇炎 | 唐奈-巴罗综合征 | 唐氏综合症 | 唾液腺炎 | 唾液酸贮积症 | 喜树属 | 嗜睡症 | 嗜酸性粒细胞增多 | 嗜酸性粒细胞增多综合征 | 嗜酸性粒细胞性哮喘 | 嗜铬细胞瘤 | 噬血细胞性淋巴组织细胞增多症 | 囊尾蚴病 | 囊肿 | 四肢带状肌营养不良症 | 四肢瘫痪 | 围产期心肌病 | 圆锥角膜 | 地中海贫血 | β地中海贫血 | 地球物理发育不良 | 地面上布满了白点 | 坎图综合征 | 坏死性小肠结肠炎 | 坏死性自身免疫性肌病 | 坏疽性脓皮病 | 垂体侏儒症 | 垂体机能减退症 | 垂体柄中断综合征 | 垂体疾病 | 埃利斯-范克里维尔德综合征 | 埃勒斯-当洛斯综合征 | 埃勒斯-当洛斯综合征伴进行性脊柱后侧凸、肌病和听力损失 | 埃尔德海姆-切斯特病 | 埃布斯坦异常 | 埃文斯综合症 | 埃默里-德赖弗斯肌营养不良症 | 基底神经节疾病 | 生物素反应性基底神经节疾病 | 基底细胞痣综合征 | 基底节脑血管疾病 | 基质性角膜营养不良 | 塔普综合征 | 塔顿-布朗-拉曼综合征 | 塞德尼克综合征 | 塞萨里综合征 | 增强型S锥综合征 | 增殖性玻璃体视网膜病变 | 墨蝶呤还原酶缺乏症 | 复发性呼吸道乳头状瘤病 | 复发性多软骨炎 | 外侧脑膜膨出综合征 | 外周T细胞淋巴瘤 | 外斜视 | 外生骨疣 | 外耳道炎 | 外胚层发育不良 | 外阴阴道炎 | 多中心腕跗骨溶解综合征 | 多发性硬化症 | 原发性进行性多发性硬化症 | 复发缓解型多发性硬化症 | 慢性进行性多发性硬化症 | 继发性进行性多发性硬化症 | 多发性神经根病 | 多发性神经病 | 多发性肌炎 | 多发性错构瘤综合征 | 多发性骨骺发育不良 | 多发性骨髓瘤 | 多囊卵巢综合征 | 多囊性肾发育不良 | 多囊肝 | 常染色体显性遗传多囊肾 | 常染色体隐性遗传多囊肾 | 多小脑回 | 多形性胶质母细胞瘤 | 多形性黄色星形细胞瘤 | 多形红斑 | 多指症 | 多灶性运动神经病 | 多瘤病毒肾病 | 多种先天性异常-张力减退-癫痫综合征2 | 多种硫酸酯酶缺乏症 | 多系统平滑肌功能障碍综合征 | 多系统萎缩 | 大口病2 | 大疱性类天疱疮 | 大疱性表皮松解症 | 大颗粒淋巴细胞白血病 | 大骨节病 | 大麻滥用 | 天使主义 | 天使综合症 | 天冬氨酰糖胺尿 | 天疱疮 | 失智 | 失用症 | 失神性癫痫 | 失语症 | 头痛 | 奇塔亚特综合征 | 奈梅亨断裂综合征 | 奥利尔病 | 奥姆斯特德综合征 | 宫外孕妊娠 | 妊娠期糖尿病 | 妊娠滋养细胞疾病 | 威克-沃尔夫综合征 | 威尔-马切萨尼综合征 | 威尔逊氏病 | 威廉姆斯综合症 | 威斯科特-奥尔德里奇综合征 | 婴儿Refsum病 | 婴儿期癫痫伴迁移性局灶性发作 | 婴儿痉挛症 | 婴儿神经轴突营养不良 | 婴儿肝衰竭综合征1 | 婴儿肾病胱氨酸病 | 子宫内膜增生 | 子宫内膜异位症 | 子宫内膜炎 | 子宫肌瘤 | 子宫腺肌病 | 子痫 | 孔脑畸形 | 孢子虫发育不良 | 季节性情绪障碍 | 学习障碍 | 安特利-比克斯勒综合征 | 室管膜瘤 | 室间隔缺损 | 宫颈炎 | 家族性低β脂蛋白血症 | 家族性偏瘫性偏头痛 | 家族性嗜铬细胞瘤-副神经节瘤 | 家族性地中海热 | 家族性孤立性甲状旁腺功能亢进症 | 家族性指关节病-短指 | 家族性水平性凝视麻痹，伴有进行性脊柱侧凸，2 | 家族性渗出性玻璃体视网膜病变 | 家族性男性性性早熟 | 家族性睡眠时相提前综合征 | 家族性糖皮质激素缺乏症 | 家族性肥厚型心肌病 | 家族性胸主动脉瘤 | 家族性脑淀粉样血管病 | 家族性自主神经功能障碍 | 家族性视网膜动脉大动脉瘤 | 家族性部分性脂肪营养不良 | 家族性醛固酮增多症 | 家族性阵发性疼痛综合征 | 寒冷出汗综合症 | 寻常型天疱疮 | 寻常痤疮 | 导致压力性麻痹的遗传性神经病 | 小头型原始侏儒症 | 小头畸形 | 癫痫发作和发育迟缓小头畸形 | 小头骨发育不良原始侏儒症，I 型 | 小头骨发育不良原始侏儒症，II 型 | 小汗腺汗孔癌 | 小淋巴细胞淋巴瘤 | 小眼症 | 小眼症，综合征 7 | 小耳症 | 开曼型小脑性共济失调 | 小脑面齿综合征 | 小阴茎 | 少弱精子症 | 少星形细胞瘤 | 少毛症 | 少汗性外胚层发育不良 | 少突胶质细胞瘤 | 少精症 | 尘肺 | 尚病 | 尤因肉瘤 | 尼古丁依赖 | 尼古丁成瘾 | 尼古拉德斯-巴雷策综合征 | 尼曼-匹克病 | A 型尼曼-匹克病 | B 型尼曼-匹克病 | 尿崩症 | 神经源性尿崩症 | 尿毒症 | 尿毒症瘙痒症 | 尿石症 | 尿素循环障碍 | 尿道下裂 | 尿道炎 | 尿面综合征 | 局灶性皮质发育不良 2 型 | 局灶性真皮发育不全 | 局灶性肌炎 | 局灶性面部真皮发育不良 | 局灶节段性肾小球硬化 | 局限性硬皮病 | 岩藻糖苷沉积症 | 川崎病 | 左心发育不良综合征 | 左心室致密化不全 | 巨人症 | 巨噬细胞性肌筋膜炎 | 巨噬细胞活化综合征 | 巨囊藻-小结肠-肠蠕动低下综合征 | 巨大轴突神经病 | 巨幼细胞性贫血 | 巨指症 | 巨细胞动脉炎 | 巨细胞胶质母细胞瘤 | 巨脑畸形 | 巩膜炎 | 巩膜角膜 | 巴代-比德尔综合征 | 巴拉卡特综合征 | 巴桑综合征 | 巴比龙-勒斐尔综合征 | 巴特综合症 | 巴索卡斯-帕帕斯综合征 | 巴贝斯虫病 | 巴雷特食管 | 巴顿病 | 布伦纳瘤 | 布加综合征 | 布劳综合征 | 布卢姆综合症 | 布鲁克-斯皮格勒综合征 | 布鲁克综合症 | 布鲁格达综合征1 | 帕廷顿综合征 | 帕斯利病 | 帕金森病 | 帕金森病6型，常染色体隐性遗传，早发型 | 帕金森症 | 常染色体隐性遗传先天性鱼鳞病 | 常染色体隐性遗传病 | 常染色体隐性遗传痉挛性截瘫35型 | 常染色体隐性遗传痉挛性截瘫54型 | 常染色体隐性遗传痉挛性截瘫75型 | 常见变异型免疫缺陷病 | 干燥综合征 | 干骺端软骨发育不良，Schmid 型 | 平滑肌瘤 | 平滑肌肉瘤 | 平衡失调综合征 | 并指多指症 | 并指畸形 | 幼年型粒单核细胞白血病 | 幼年型透明纤维瘤病 | 幼年型黄色肉芽肿 | 幼年性息肉病 | 幼淋巴细胞白血病 | 婴儿肥厚性幽门狭窄 | 广场恐惧症 | 库拉里诺综合征 | 库欣综合征 | 庞贝病 | 康恩综合征 | 开角型青光眼 | 异丁酰辅酶A脱氢酶缺乏症 | 异位晶状体，孤立的，常染色体隐性遗传 | 异位骨化 | 异向性 | 异常纤维蛋白原血症 | 异戊酸血症 | 异染性脑白质营养不良 | 异皮病伴中性粒细胞减少症 | 弓形体病 | 弗兰克-特哈尔综合征 | 弗雷泽综合症 | 弥散性血管内凝血 | 弥漫性内质性脑桥胶质瘤 | 弥漫性掌跖角化病 | 弥漫性特发性肺神经内分泌细胞增生 | 弥漫性系膜硬化 | 弱视 | 强直性肌病 | 强迫症 | 彭德雷德综合征 | 影像综合征 | 彼得斯加综合征 | 微绒毛包涵体病 | 微综合症 | 德布奎综合征 | 心内膜炎 | 心包炎 | 心境恶劣 | 心房颤动 | 心椎颈面综合征 | 心绞痛 | 心肌梗塞 | 心肌炎 | 扩张型心肌病 | 心脏传导阻滞 | 心脏停搏 | 心脏结节病 | 心脏衰竭 | 心脏间隔缺损 | 心面皮肤综合征 | 快速眼动睡眠行为障碍 | 念珠菌 | 急性全身发疹性脓疱病 | 急性冠状动脉综合征 | 急性前葡萄膜炎 | 急性淋巴细胞白血病 | 急性白血病 | 急性粒细胞白血病 | 急性肺损伤 | 急性肾小管坏死 | 急性肾损伤 | 急性胸部综合症 | 急性运动轴突神经病 | 性早熟 | 性腺功能减退症 | 恐慌症 | 恶性周围神经鞘瘤 | 恶性纤维组织细胞瘤 | 恶性贫血 | 情绪障碍 | 惊厥过度 | 惊叫综合症 | 惠普尔病 | 感染性腹泻 | 感觉性共济失调神经病、构音障碍和眼肌麻痹 | 感觉神经母细胞瘤 | 感觉神经病 | 感音神经性听力损失 | 慢性丙型肝炎 | 慢性中性粒细胞白血病 | 慢性乙型肝炎 | 慢性支气管炎 | 慢性淋巴细胞白血病 | 慢性炎症性脱髓鞘性多发性神经病 | 慢性牙周炎 | 慢性特发性骨髓纤维化 | 慢性白血病 | 慢性皮肤粘膜念珠菌病 | 慢性粒单核细胞白血病 | 慢性粒细胞白血病 | 慢性肉芽肿病 | 慢性肝炎 | 慢性肾病 | 慢性胰腺炎 | 慢性血栓栓塞性肺动脉高压 | 慢性铍病 | 憩室炎 | 戈萨尔综合征 | 戈谢病 | 戊二酸尿症1型 | 戊二酸尿症3型 | 戊型肝炎 | 成人多聚葡萄糖体病 | 成神经细胞瘤 | 成釉细胞瘤 | 成釉细胞癌 | 成骨不全症 | 戒断综合症 | 截瘫 | 戴蒙德-布莱克范贫血 | 房室间隔缺损 | 房间隔缺损 | 扁平苔藓 | 扁桃体炎 | 手足裂畸形 | 抗NMDA受体脑炎 | 抗凝血酶 III 缺乏症 | 抗合成酶综合征 | 抗磷脂综合征 | 抗精神病药恶性综合征 | 抗肾小球基底膜疾病 | 报春花综合症 | 抽动症 | 拇指三指骨多指并指综合征 | 拉森综合征 | 拉沙热 | 拉福拉病 | 拔毛癖 | 持续性原发性玻璃体增生 | 持续性苗勒氏管综合征 | 持续的胎儿循环 | 指甲-髌骨综合征 | 非综合征性先天性指甲疾病 | 指趾外翻 | 掌腱膜挛缩症 | 掌跖角化病 | 接合菌病 | 接触性皮炎 | 播散性浅表光化性汗孔角化病 | 支气管扩张 | 支气管炎 | 放线菌属 | 教练综合症 | 散光 | 散发性偏瘫性偏头痛 | 散发性包涵体肌炎 | 斑秃 | 斜视