Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C1C(=O)O[C@@H]2/C=C(\COC(=O)C(C)C)CC/C=C(\CO)C(=O)C[C@@H]12 Value: =12.5uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C1C(=O)O[C@@H]2/C=C(\COC(=O)C(C)C)CC/C=C(\CO)[C@H](O)C[C@@H]12 Value: =100uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C[C@]1(C)CC[C@H]2C(=C)C(=O)O[C@@H]2[C@H]1C(=C)C Value: =100uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C1C(=O)O[C@H]2/C=C(\C)CC/C=C(\C)[C@@H](OC(=O)/C(C)=C/C)[C@H](O)[C@@H]12 Value: =100uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C1C(=O)O[C@@H]2C[C@@]3(C)CC(=O)C(OC(C)=O)=C(C)C3C[C@H]12 Value: =100uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C1C(=O)O[C@@H]2C[C@@]3(C)[C@H](OC(C)=O)CC[C@](O)(COC(=O)C(C)C)[C@@H]3C[C@H]12 Value: =100uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C1C(=O)O[C@H]2[C@H]1CC[C@@]1(C)[C@@H](O)C[C@@H](O)C(=C)[C@H]21 Value: =100uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C1C(=O)O[C@H]2[C@H]1CC[C@]1(C)[C@@H]2C(C)=CC[C@H]1O Value: =100uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C1C(=O)O[C@]23C[C@H]1CCC(COC(C)=O)=C2C(=O)C=C3C Value: =100uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C(C)C(=O)O[C@H]1[C@@H]2[C@H](C)C(=O)O[C@@H]2C[C@@H](C)[C@@H]2C=CC(=O)[C@@]12C Value: =100uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C/C=C(\C)C(=O)O[C@H]1[C@@H]2[C@H](C)C(=O)O[C@@H]2C[C@@H](C)[C@@H]2C=CC(=O)[C@@]12C Value: =100uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C1C(=O)O[C@H]2[C@H]1CCC(C)=C1C(=O)C=C(CO)[C@@H]12 Value: =50uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C1C(=O)O[C@H]2[C@H]1[C@@H](O)C[C@@](C)(O)[C@@H]1CC=C(C)[C@H]21 Value: =100uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: CC[C@@H](C)[C@@]1(O)O[C@H]2C[C@@]3(C)OC(=CC3=O)/C(CO)=C\[C@H]3OC(=O)[C@@]1(C)C23 Value: =100uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C1C(=O)O[C@H]2C/C(CO)=C/CC/C(COC(=O)C(C)CO)=C/C[C@H]12 Value: =100uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C(C)C(=O)O[C@@H]1[C@@H](OC)/C(C=O)=C\CCC(=C)[C@H](O)[C@H]2OC(=O)C(=C)[C@@H]21 Value: =50uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C1C(=O)O[C@H]2/C=C(\C)CC/C=C(/C)C(=O)[C@H](OC(=O)[C@@]3(C)O[C@H]3C)[C@@H]12 Value: =50uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C1C(=O)O[C@H]2/C=C(\C)CC/C=C(\C)[C@@H](OC(=O)[C@@]3(C)O[C@H]3C)[C@H](O)[C@@H]12 Value: =50uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C1C(=O)O[C@@H]2/C=C(/C)[C@]3(O)O[C@@](C)(C[C@@H]3O)C[C@@H](OC(=O)/C(C)=C\C)[C@@H]12 Value: =50uM Source: Homo sapiens
	Assay: Inhibition of NF-kappaB DNA binding by EMSA Type: IC100 SMILES: C=C1C(=O)O[C@@H]2C[C@@H](C)[C@@H]3[C@H](OCC)CC(=O)[C@@]3(C)[C@H](OC(C)=O)[C@H]12 Value: =50uM Source: Homo sapiens

Note: If you'd like to learn how our AI-powered BDE-Chem can help design therapeutic molecules against the RELA target, that break through the existing patents, at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai

Molecules for More Common Targets

ABCB1 | ABCG2 | ACE2 | AHR | AKT1 | ALK | AR | ATM | BAX | BCL2 | BCL2L1 | BRAF | BRCA1 | CASP3 | CASP9 | CCL5 | CCND1 | CD274 | CD4 | CDKN1A | CXCL8 | CXCR4 | DNMT1 | EGF | EGFR | EP300 | ERBB2 | ESR1 | EZH2 | FN1 | FOXO3 | HDAC9 | HGF | HMGB1 | HSP90AA1 | HSPA5 | IDO1 | IGF1 | IGF1R | IL17A | IL6 | INS | JUN | KRAS | MAPK1 | MAPK14 | MAPK3 | MAPK8 | MAPT | MCL1 | MMP9 | MTOR | MYC | NFE2L2 | NLRP3 | NOTCH1 | PARP1 | PCNA | PDCD1 | PLK1 | PRKAA1 | PRKAA2 | PTEN | PTGS2 | PTK2 | RELA | SIRT1 | SRC | STAT1 | STAT3 | STAT5A | TERT | TLR4 | TNF | TP53 | TXN | VEGFA | YAP1