Other Name(s): PARP
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:NC(=O)c1cccc2[nH]c(-c3ccc(Cl)cc3)nc12
Value:=3nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:COc1ccc(-c2nc3c(C(N)=O)cccc3[nH]2)cc1O
Value:=2nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:NC(=O)c1cccc2[nH]c(-c3ccc(C(=O)O)cc3)nc12
Value:=290nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:CN(C)c1ccc(-c2nc3c(C(N)=O)cccc3[nH]2)cc1
Value:=5.8nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:CCOC(=O)c1ccc(-c2nc3c(C(N)=O)cccc3[nH]2)cc1
Value:=8.1nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:NC(=O)c1cccc2[nH]c(-c3ccccc3C(F)(F)F)nc12
Value:=190nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:COc1ccc(-c2nc3c(C(N)=O)cccc3n2C)cc1
Value:=32nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:NC(=O)c1cccc2[nH]c(-c3ccc(C(F)(F)F)cc3)nc12
Value:=1.2nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:NC(=O)c1cccc2[nH]c(-c3cccc(C(F)(F)F)c3)nc12
Value:=8nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:NC(=O)c1cccc2[nH]c(-c3ccccc3)nc12
Value:=15nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:COc1cc(-c2nc3c(C(N)=O)cccc3[nH]2)ccc1O
Value:=13nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:NC(=O)c1cccc2[nH]c(-c3ccc4c(c3)OCO4)nc12
Value:=5.9nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:NC(=O)c1cccc2[nH]c(-c3cccc(CO)c3)nc12
Value:=6.8nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:C=CCOc1cc(-c2nc3c(C(N)=O)cccc3[nH]2)ccc1OC
Value:=9.4nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:NC(=O)c1cccc2[nH]c(-c3ccccc3F)nc12
Value:=9nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:Cc1nc2c(C(N)=O)cccc2[nH]1
Value:=99nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:COc1ccccc1-c1nc2c(C(N)=O)cccc2[nH]1
Value:=126nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:NC(=O)c1cccc2[nH]cnc12
Value:=95nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:NC(=O)c1cccc2[nH]c(-c3ccc(O)cc3)nc12
Value:=6nM
Source:
Assay:In vitro inhibition against human full length PARP protein
Type:Ki
SMILES:COc1ccc(-c2nc3c(C(N)=O)cccc3[nH]2)cc1
Value:=6.8nM
Source:

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