Disease

Neuronal Ceroid Lipofuscinosis

About the Disease
Neuronal Ceroid Lipofuscinosis, also known as hereditary ceroid lipofuscinosis, is related to ceroid lipofuscinosis, neuronal, 10 and ceroid lipofuscinosis, neuronal, 3, and has symptoms including myoclonus, seizures and abnormality of extrapyramidal motor function. An important gene associated with Neuronal Ceroid Lipofuscinosis is CLN3 (CLN3 Lysosomal/Endosomal Transmembrane Protein, Battenin). The drugs Cysteamine and Acetylcysteine have been mentioned in the context of this disorder. Affiliated tissues include retina, brain and spleen, and related phenotypes are no effect and no effect

Common Targets
NPM1 | CTSF | TPP1 | CLN3 | KCTD7 | CLN6 | TGM2 | CLN8 | CLCN2 | RORB | CLN5 | GRN | Glutamate Receptor Ionotropic AMPA Receptor | TTPA | MFSD8 | PPARA | PPT1 | DNAJC5 | RARS2 | CTSD

疾病靶点研报
Neuronal Ceroid Lipofuscinosis

Note: If you'd like to get a target analysis report for Neuronal Ceroid Lipofuscinosis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Neuronal Ceroid Lipofuscinosis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Retinopathy Of Prematurity | Renpenning Syndrome | Spinocerebellar Ataxia Type 15 | Dysmorphophobia | Osteogenesis Imperfecta Type IV | Muscle Wasting | Episodic Ataxia | Heterotopic Ossification | Exocrine Pancreatic Insufficiency | Vici Syndrome | Spinocerebellar Ataxia Type 6 | Meningitis | Hydronephrosis | Pulmonary Veno-occlusive Disease | Neuropathy | Persistent Fetal Circulation | Agoraphobia | Norrie Disease | Polycystic Kidney, Autosomal Recessive | Thrombasthenia | GNE Myopathy | Keratosis, Seborrheic | Myhre Syndrome | Spinal Muscular Atrophy Type 3 | Hypotonia-cystinuria Syndrome | Diabetes Insipidus | Pseudohypoparathyroidism Type 1C | Situs Inversus | Albinism | Schaaf-Yang Syndrome | Orthostatic Intolerance | Eccrine Porocarcinoma | Hermansky-Pudlak Syndrome | Pyruvate Carboxylase Deficiency Disease | Papillon-Lefevre Syndrome | Cold-induced Sweating Syndrome | Microcephaly | Osteitis | Spinocerebellar Ataxia Type 8 | Dyslexia | Early Infantile Epileptic Encephalopathy 1 | Tularemia | Galactosemia | Pemphigoid | Hyperbilirubinemia, Neonatal | Gyrate Atrophy Of The Choroid And Retina | Wolfram Syndrome 2 | Familial Hypobetalipoproteinemia | Histiocytic Sarcoma | CHARGE Syndrome | Barrett Esophagus | Infectious Diarrhea | Carpenter Syndrome | Protein S Deficiency | Cervical Dystonia | Tatton-Brown-Rahman Syndrome | Birt-Hogg-Dube Syndrome | Hyper IgE Syndrome | Oligodendroglioma | Tyrosinemia | Congenital Bilateral Absence Of Vas Deferens | Obesity | Raine Syndrome | Pantothenate Kinase-associated Neurodegeneration | Progressive Familial Intrahepatic Cholestasis | Intestinal Obstruction | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Heart Septal Defects | Pendred Syndrome | Inflammatory Linear Verrucous Epidermal Nevus | Cryoglobulinemia | Neurofibroma, Plexiform | Leber Congenital Amaurosis | Pemphigus Foliaceus | Phenylketonuria | Hypohidrotic Ectodermal Dysplasia, X-linked | Leigh Syndrome | Familial Thoracic Aortic Aneurysm | Esophageal Motility Disorders | Intermittent Claudication | Kaposiform Hemangioendothelioma | Autoimmune Autonomic Ganglionopathy | GAPO Syndrome | Ellis-Van Creveld Syndrome | DRESS Syndrome | Prolactinoma | Focal Facial Dermal Dysplasia | Glycogen Storage Disease Type 0, Muscle | Osteoglophonic Dysplasia | Mood Disorder | Anti-glomerular Basement Membrane Disease | Fanconi Anemia | Paroxysmal Kinesigenic Dyskinesia | Stickler Syndrome | Meesmann Corneal Dystrophy | Necrotizing Autoimmune Myopathy | Presbycusis | NDH Syndrome | Nephrosclerosis | Anorectal Malformations | Pneumococcal Meningitis | Sarcomatoid Carcinoma Of The Lung | Lichen Planus | Geleophysic Dysplasia | Budd-Chiari Syndrome | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Atopy | Crouzon Syndrome With Acanthosis Nigricans | Neurofibromatosis Type 1 | Speech Disorders | Mitochondrial Encephalomyopathy | Neuronal Ceroid Lipofuscinosis | Lamellar Ichthyosis | Erythema Multiforme | Obsessive-compulsive Disorder | Hyperinsulinemic Hypoglycemia | Chronic Leukemia | Glutathione Synthetase Deficiency | Nephrotic Syndrome Type 1 | Hypercalcemia | Hypertension, Essential | Desmosterolosis | Ectodermal Dysplasia | Sitosterolemia | Hairy Cell Leukemia | Vitelliform Macular Dystrophy | Sengers Syndrome | Vaginitis | Diarrhea | Meningococcal Meningitis | Onchocerciasis | Multiple Myeloma | Lipodystrophy | Myelomeningocele | Seminoma | Supravalvular Aortic Stenosis | Hypospadias | Postaxial Polydactyly | Cryptosporidiosis | Systemic Lupus Erythematosus | Pulmonary Alveolar Proteinosis | Frank-ter Haar Syndrome | Stevens-Johnson Syndrome | Leprosy | Blomstrand Osteochondrodysplasia | Facioscapulohumeral Muscular Dystrophy Type 2 | PASLI Disease | Bicuspid Aortic Valve | Mandibuloacral Dysplasia With Type A Lipodystrophy | Usher Syndrome Type III | Oral Lichen Planus | Spinocerebellar Ataxia Type 10 | Mitochondrial Disease | Systemic Mastocytosis | Premenstrual Syndrome | Central Retinal Artery Occlusion | Dentinogenesis Imperfecta | Hidradenitis | Retinal Telangiectasia | Juvenile Polyposis | Hartnup Disease | Progressive Familial Intrahepatic Cholestasis Type 3 | Osteogenesis Imperfecta Type II | Weill-Marchesani Syndrome | Esophageal Carcinoma | Ureteropelvic Junction Obstruction | Postpoliomyelitis Syndrome | Charcot-Marie-Tooth Disease, Type 2 | Sezary Syndrome | Large Granular Lymphocytic Leukemia | Uveitis | Purpura | Corneal Edema | Macular Degeneration | Sleep Disorder | Walker-Warburg Syndrome | Duchenne Muscular Dystrophy | Chordoma | Metaphyseal Chondrodysplasia, Schmid Type | Polycythemia | Neuromuscular Disorders | Cornelia De Lange Syndrome | Tay-Sachs Disease | Benign Familial Neonatal Convulsions | Multiple Sclerosis | Lassa Fever | Leukoencephalopathy, Progressive Multifocal | Oligoastrocytoma | Gestational Trophoblastic Disease | Giant Cell Arteritis | Cardiac Sarcoidosis | Hemochromatosis Type 1 | Pyruvate Kinase Deficiency | Temtamy Preaxial Brachydactyly Syndrome | Anorchia | Protein C Deficiency | Glaucomatocyclitic Crisis | Zimmermann-Laband Syndrome | Stroke, Ischemic | Myositis | Asthma | Gastrointestinal Disorders | Cranioectodermal Dysplasia | Pulmonary Sclerosing Hemangioma | Argininosuccinic Aciduria | Hennekam Lymphangiectasia-lymphedema Syndrome | Bone Marrow Necrosis | Heavy Chain Disease | Coffin-Lowry Syndrome | Anencephaly | Spitz Nevus | Hereditary Folate Malabsorption | Cardiomyopathy, Peripartum | Craniolenticulosutural Dysplasia | Noonan Syndrome-like Disorder With Loose Anagen Hair | Smith-Lemli-Opitz Syndrome | Asperger Syndrome | Epidermolytic Ichthyosis, Annular | Congenital Heart Block | Batten Disease | Heterotaxy | LEOPARD Syndrome | Carcinoma In Situ | Scleroderma | Choriocarcinoma | Sulfite Oxidase Deficiency | B-cell Chronic Lymphocytic Leukemia | Currarino Syndrome | Celiac Disease | Bartsocas-Papas Syndrome | Enhanced S-cone Syndrome | Paternal Uniparental Disomy Of Chromosome 14 | Thrombocythemia, Essential | Postpartum Depression | Hidradenitis Suppurativa | Periventricular Leukomalacia | Glioma | Silver-Russell Syndrome | Glutaric Aciduria Type 1 | Seizures | Spastic Paraplegia Type 7 | Hypocalcemia | Mitochondrial DNA Depletion Syndrome 13 | Hypodontia | Hemochromatosis | Thyrotoxic Periodic Paralysis | Uremia | Myocarditis | Hydrops Fetalis | Spinal Muscular Atrophy | Metabolic Diseases | Whipple's Disease | Costello Syndrome | Hepatic Steatosis | Spondyloperipheral Dysplasia | Chronic Myeloid Leukemia | Rothmund-Thomson Syndrome | Cutaneous Lupus Erythematosus | Autoimmune Polyendocrinopathy Syndrome Type I | Hypertensive Retinopathy | Cystinuria | Lysosomal Acid Lipase Deficiency | C3 Glomerulopathy | CREST Syndrome | Erythrokeratodermia Variabilis | Muir-Torre Syndrome | Cataract | Marinesco-Sjogren Syndrome | Blepharo-cheilo-odontic Syndrome | Episodic Ataxia Type 1 | Menkes Disease | Polymyalgia Rheumatica | Cerebrovascular Disorders | Camptocormia | Kabuki Syndrome | Ocular Hypertension | Leukodystrophies | Mast Cell Leukemia | Portal Vein Thrombosis | Myopia | Donnai-Barrow Syndrome | Epithelial-myoepithelial Carcinoma | Autoimmune Disease | Glutaric Aciduria Type 3 | Pierpont Syndrome | Cellulitis | Cavitary Optic Disc Anomalies | Alopecia | Cancer, Skin | Multiple Epiphyseal Dysplasia | Chromosome 8q21.11 Deletion Syndrome | Urea Cycle Disorder | Familial Digital Arthropathy-brachydactyly | MELAS Syndrome | Epidermolysis Bullosa Dystrophica | Richter's Syndrome | Chromosome 16p11.2 Deletion Syndrome | Ocular Albinism Type 1 | Genee-Wiedemann Syndrome | Basan Syndrome | Tyrosinemia Type 2 | Kernicterus | Primary Erythromelalgia | Migraine | Otitis Media | Smith-Magenis Syndrome | Fetal Akinesia Deformation Sequence | Coffin-Siris Syndrome | Disseminated Superficial Actinic Porokeratosis | Bursitis | Astigmatism | Schizophrenia, Paranoid | Fetal And Neonatal Alloimmune Thrombocytopenia | Epidermolysis Bullosa | Nance-Horan Syndrome | Chorioretinitis | Hypertension, Renovascular | Frontometaphyseal Dysplasia | Oculopharyngeal Muscular Dystrophy | Saul-Wilson Syndrome | Fragile X Syndrome | Gout | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Irritable Bowel Syndrome | Goldenhar Syndrome | Spondylo-ocular Syndrome | Neurotoxicity | Tangier Disease | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Teratozoospermia | Hereditary Sensory Neuropathy Type 1 | Inflammatory Bowel Disease | X-linked Creatine Transporter Deficiency | Cheilitis | Charcot-Marie-Tooth Disease Type 2T | Angioedema | Cutaneous T-cell Lymphoma | Herpes Simplex Dermatitis | Diabetes Insipidus, Nephrogenic | Alpha-mannosidosis | Botulism | Poretti-Boltshauser Syndrome | Autosomal Recessive Congenital Ichthyosis | Leukocyte Adhesion Deficiency | McLeod Syndrome | Fibrillation, Atrial | Anuria | Paronychia | Anosmia, Congenital | Osteopetrosis | Vestibular Disease | Chromosome 9q34.3 Deletion Syndrome | Seborrheic Dermatitis | Neurofibromatosis | Familial Retinal Arterial Macroaneurysm | Huntington's Disease | Fontaine Progeroid Syndrome | Diastrophic Dysplasia | Arthritis | Encephalitis, Tick-borne | Methemoglobinemia | Eosinophilia | Transthyretin-related Amyloidosis | Tardive Dyskinesia | Schuurs-Hoeijmakers Syndrome | Lymphoma, B-cell | Peripheral T-cell Lymphoma | Cardiofaciocutaneous Syndrome | Hyperhomocysteinemia | Hepatitis A | Keratoacanthoma | Mucolipidosis Type III | Anovulation | Eosinophilic Asthma | Infantile Neuroaxonal Dystrophy | ACTH-independent Macronodular Adrenal Hyperplasia | Cantu Syndrome | Insulin Resistance | Mesothelioma, Malignant | Chronic Enteropathy Associated With SLCO2A1 Gene | Presbyopia | Dubin-Johnson Syndrome | Leri-Weill Dyschondrosteosis | Mumps | Spinocerebellar Ataxia Type 38 | Metanephric Adenoma | Allan-Herndon-Dudley Syndrome | Carcinoid Syndrome | Rickets | Kawasaki Disease | Aspergillosis | Pilomatrix Carcinoma | Noonan Syndrome | Hereditary Hemorrhagic Telangiectasia | Pre-eclampsia | Mitochondrial DNA Depletion Syndrome | Thyroiditis, Autoimmune | Wolff-Parkinson-White Syndrome | Gingivitis | T-cell Leukemia