Microcephaly

About the Disease
Microcephaly, also known as microencephaly, is related to primary autosomal recessive microcephaly and primary microcephaly. An important gene associated with Microcephaly is ASPM (Assembly Factor For Spindle Microtubules), and among its related pathways/superpathways are "Cell Cycle, Mitotic" and Chromatin Regulation / Acetylation. Affiliated tissues include brain, cortex and fetal brain, and related phenotypes are growth/size/body region and nervous system

Common Targets
D2HGDH | TRIM14 | KNL1 | TMX2 | WDR73 | PAH | POMT1 | G367 | ASPM | STAMBP | WARS1 | DYRK1A | WDR62 | RABGAP1L | RSAD2 | PCDHGC4 | TRAPPC14 | AP4B1 | HERC5 | MFSD2A | TBCD | MECP2 | WDR81 | WDR47 | LINS1 | SLFN12L | NCAPD2 | THOC6 | PAK3 | CENPF | CIT | TRAPPC9 | CKAP2L | SLC13A5 | SARS1 | MCPH1 | ORC1 | MSI1 | NUP133 | AP4S1 | PDCD6IP | DHX58 | SEMA4D | CTNNB1 | NUP37 | RRP7A | MX1 | QARS1 | SASS6 | PHC1 | CEP152 | CDK5RAP2 | STIL | KIF11 | NDE1 | RTTN | CENPJ | COLEC12 | DDX60 | KIF14 | IFIH1 | CEP135 | XRCC4 | PPP1R35 | CASK | PARP14 | VRK1 | ATP9A | ISG15 | NARS1 | DEAF1 | WDFY3 | PLK4 | ZNF335 | KIF1A | TUBGCP4 | ZBTB18 | KLHDC7B | PPP1R15B | CDK6 | PQBP1 | EFTUD2 | ANKLE2 | COPB2 | AP4E1 | DIAPH1 | DNMT3A | GPKOW | OAS1 | IER3IP1

Note: If you'd like to get a target analysis report for Microcephaly, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Microcephaly at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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