Protein C Deficiency

About the Disease
Protein C Deficiency, also known as congenital thrombotic disease, due to protein c deficiency, is related to budd-chiari syndrome and vitamin k deficiency bleeding. An important gene associated with Protein C Deficiency is PROC (Protein C, Inactivator Of Coagulation Factors Va And VIIIa), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Protein C and Fibrinolytic Agents have been mentioned in the context of this disorder. Affiliated tissues include skin, liver and bone marrow, and related phenotypes are Synthetic lethal with vaccinia virus (VACV) infection and homeostasis/metabolism

Common Targets
PROC | F5

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