Disease

Urea Cycle Disorder

About the Disease
Urea Cycle Disorder, also known as urea cycle disorders, inborn, is related to carbamoyl phosphate synthetase i deficiency, hyperammonemia due to and n-acetylglutamate synthase deficiency. An important gene associated with Urea Cycle Disorder is SLC25A13 (Solute Carrier Family 25 Member 13), and among its related pathways/superpathways are Metabolism and Regulation of expression of SLITs and ROBOs. The drugs 4-phenylbutyric acid and Protective Agents have been mentioned in the context of this disorder. Affiliated tissues include brain, liver and prefrontal cortex, and related phenotypes are no effect and no effect

Common Targets
DAO | CPS1 | ARG1 | NF-kappaB (NFkB) | ACADS | Chaperone (nonspecified subtype) | NAGS | Histone deacetylase (nonspecified subtype) | Pyruvate dehydrogenase kinase (nonspecified subtype) | OTC

疾病靶点研报
Urea Cycle Disorder

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