Disease

Eating Disorder

About the Disease
Eating Disorder, also known as eating disorders, is related to bulimia nervosa and anorexia nervosa, and has symptoms including decrease in appetite, adipsia and symptoms concerning nutrition, metabolism, and development. An important gene associated with Eating Disorder is GHRL (Ghrelin And Obestatin Prepropeptide), and among its related pathways/superpathways are GPCR downstream signalling and Signal Transduction. The drugs Zinc sulfate and Zinc cation have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and kidney, and related phenotypes are Weakly decreased NFAT1-GFP nuclear translocation and homeostasis/metabolism

Common Targets
FFAR4 | OPRK1 | CNR2 | GHSR | GRM5 | DRD4 | DRD2 | RXFP3 | Alpha-2 Adrenergic receptors (nonspecified subtype) | Neuropeptide Y receptor (NPY-R) (nonspecified subtype) | MAOA | AVPR1B | GH1 | HTR1A | CHRM1 | CNR1 | SLC6A2 | HCRTR1 | HTR2B | GRM2 | GABA(A) receptor | G2099 | Peroxisome Proliferator-Activated Receptors (PPAR) (nonspecified subtype) | Opioid receptor (nonspecified subtype) | NTRK3 | NPY2R | BCHE | ACHE | OXT | MC3R | Orexin receptor (nonspecified subtype) | NPY5R | HCRTR2 | RUFY1 | FAAH | FASN | SLC6A4 | ADCYAP1R1 | HTR6 | HRH1 | HTR2A | ACACB | HTR1B | Cannabinoid receptor (nonspecified subtype) | 5-Hydroxytryptamine Receptor 2 (5-HT2) (nonspecified subtype) | SYNE1 | MC4R | FTO | HTR2C | DRD3 | GRM4 | GLP1R | MAOB | Calcium/calmodulin-dependent protein kinase type II (CaMK-II) | SLC6A3 | GPR55 | OXTR | MCHR1 | TAAR1 | CHRM2 | Melanin-concentrating hormone (MCH) receptor (nonspecified subtype) | MC5R | CAMKK2 | MC1R | HRH3

疾病靶点研报
Eating Disorder

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