Disease

Pearson Syndrome

About the Disease
Pearson Marrow-Pancreas Syndrome, also known as pearson syndrome, is related to sideroblastic anemia and 3-methylglutaconic aciduria. An important gene associated with Pearson Marrow-Pancreas Syndrome is MT-CO2 (Mitochondrially Encoded Cytochrome C Oxidase II), and among its related pathways/superpathways are Metabolism and "Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.". The drugs Tocopherol and DL-alpha-Tocopherol have been mentioned in the context of this disorder. Affiliated tissues include Pancreas, bone marrow and bone, and related phenotypes are neutropenia and reticulocytosis

Common Targets
ACADVL | LINGO4 | RUNX1

疾病靶点研报
Pearson Syndrome

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