Acute Coronary Syndrome

About the Disease
Ischemia, also known as acute coronary syndrome, is related to limb ischemia and lipoprotein quantitative trait locus, and has symptoms including anoxemia, polydipsia and muscle weakness. An important gene associated with Ischemia is LINC01254 (Long Intergenic Non-Protein Coding RNA 1254), and among its related pathways/superpathways are Signal Transduction and Response to elevated platelet cytosolic Ca2+. The drugs Lovastatin and Nadroparin have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, heart and brain, and related phenotypes are homeostasis/metabolism and nervous system

Common Targets
CYP2C19 | PHACTR1 | ATP4B | ECHS1 | BTBD19 | VWF | SOCS1 | Integrin alphaMbeta2 (MAC-1) Receptor | F9 | IL2RA | ADAMTS7 | ATG2B | DAZAP1 | NR1H2 | SREBF2 | ZPR1 | CIITA | SMG6 | ALOX5AP | ADAMTS13 | G1432 | PRKCZ | NFATC1 | RAPGEF1 | PPARG | NOS1AP | MYOM2 | CIAO1 | AGT | MMP3 | RUNX3 | SAFB | PRDM16 | SELL | ITGA2 | ACP1 | HMGCR | ANKS1A | ARID3B | VKORC1 | MAPK11 | PTGS1 | NECAB1 | PROK2 | ATP1B1 | WIPF1 | NR3C1 | OGG1 | FPR1 | HLA-G | G9429 | PLCL1 | CCR7 | CDKN2B-AS1 | ARHGEF1 | RAB37 | ABCA1 | CCR2 | G5743 | ATG16L1 | ARHGEF9 | PCSK9 | ZSCAN25 | MED12L | NFKBIA | FLT1 | ANKRD23 | F10 | MVD | APOBEC3H | G5243 | PIEZO1 | TCF21 | G4318 | ITGB2 | Sodium channel (nonspecified subtype) | SELP | CYP24A1 | F2 | VDR | XRCC3 | POC1B | CES1 | PSRC1 | SERPINE1 | MTHFD1L | FKBP5 | SMARCA4 | LDLRAP1 | NPPA | Integrin alphaIIbbeta3 (fibrinogen gpIIb/IIIa) receptor | NOS3 | DHCR7 | HRNR | IL10 | UGT2B7 | TREM2 | PSMB1 | KDR | PRF1 | JMJD8 | CYP3A5 | GPC5 | SLC23A2 | NPPB | ANKRD11 | TCF7 | P2RY12 | NEDD9 | Serine protease (nonspecified subtype) | NADSYN1 | IL1B | AGAP3 | G7422 | NMRAL1 | IFNG | ZDHHC3 | SORCS2 | TCOF1 | TLR9 | ZFYVE28 | Kallikrein (nonspecified subtype) | FASLG | HNF1A | G3569 | TREM1 | PRKCB | CCR1 | EDN1 | APEX1 | WDR12 | TIAF1 | GGCX | DLL1 | AGTR1 | CCR5 | FPR2 | KARS1 | PON1 | GC | SLCO1B1 | CCL18 | ITGB3 | EFR3A | APOE | CYP2B6 | PLIN1 | PLA2G2D | CASP1 | G114548 | ZC3HC1 | CYP4F2 | F11 | Phospholipase A2, Secretory (sPLA2) (nonspecified subtype) | IL6R | KLKB1 | FYN | F2R | FIG4 | XRCC1 | F7 | APLN | DNAJB13 | DEDD2 | RARG | PEAR1 | CRP | PDGFA | PCNT | LPA | MRAS | SCN5A | CYP27B1 | ACACA | MMP1 | FOXP3 | PTAFR | MPO | MIA3 | NFKB1 | CNNM2 | LIPG | RGS3 | IL2RB | SLC5A9 | UCP2 | G7124 | CYP3A4 | ENPP2 | PLPP3 | PPIA | ITGAM | ERCC5 | BDNF | CYBA | PLA2G2A | SLC5A2 | LDLR | G7157 | TSPEAR | LINC02910 | SLC39A8 | Fibrinogen | DGKQ | SREBF1 | HLA-DRB1 | RILPL1 | MGP | CETP

Note: If you'd like to get a target analysis report for Acute Coronary Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Acute Coronary Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Pneumonia, Mycoplasma | Vitamin K Deficiency | Myelomeningocele | Neurocutaneous Syndromes | Fibromyalgia | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Yellow Fever | Thanatophoric Dysplasia | Lennox-Gastaut Syndrome | Myelitis | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Carcinoma In Situ | Prurigo Nodularis | Hyperuricemia | Nijmegen Breakage Syndrome | Pituitary Disorders | Okihiro Syndrome | Charcot-Marie-Tooth Disease Type 2D | Vitreoretinal Degeneration, Snowflake Type | Dystonia | Rift Valley Fever | COACH Syndrome | Christianson Syndrome | Chromosome 8q21.11 Deletion Syndrome | Pseudohypoparathyroidism Type 2 | Lissencephaly 2 | Spinocerebellar Ataxia Type 3 | Charcot-Marie-Tooth Disease Type 4B1 | 5-oxoprolinase Deficiency | Pleural Tuberculosis | Niemann-Pick Disease, Type A | Vitreoretinopathy, Proliferative | Obsessive-compulsive Disorder | Primrose Syndrome | Binge Eating Disorder | Glycogen Storage Disease Type 9 | Extramammary Paget's Disease | Autoimmune Autonomic Ganglionopathy | Trichuriasis | Craniosynostosis | Oculocutaneous Albinism Type 1 | Thrombocytopenia | Aspergillosis | Hereditary Xerocytosis | Pheochromocytoma | Abetalipoproteinemia | Polymyalgia Rheumatica | Persistent Mullerian Duct Syndrome | Carbonic Anhydrase VA Deficiency | Ocular Surface Squamous Neoplasia | Liver Failure, Acute Infantile | Chronic Kidney Disease | Spitzoid Melanoma | Retinitis | Actinomycetoma | Myelitis, Transverse | Beckwith-Wiedemann Syndrome | Open-angle Glaucoma | Combined Malonic And Methylmalonic Acidemia | Thanatophoric Dysplasia Type 1 | Infertility, Male | Galactosialidosis | Rheumatoid Arthritis | Early Infantile Epileptic Encephalopathy | Twin-to-twin Transfusion Syndrome | Coronary Artery Disease | Tuberculosis | Peutz-Jeghers Syndrome | Overactive Bladder | Diabetes Insipidus, Neurogenic | Wolman Disease | Huntington's Disease-like 2 | Bronchiolitis | Myocarditis | Hyperkeratosis | Central Core Disease | Renal Medullary Carcinoma | Hypertensive Nephropathy | Clouston Hidrotic Ectodermal Dysplasia | Shock, Cardiogenic | Mesothelioma, Malignant | Polycystic Liver | Parkinson Disease 6, Autosomal Recessive Early-onset | Hypodontia | Priapism | Glutaric Aciduria Type 1 | Cerebral Amyloid Angiopathy | Pseudoachondroplasia | Hereditary Mixed Polyposis Syndrome | Hemolytic Anemia | Leukodystrophies | Trichomegaly | Leri-Weill Dyschondrosteosis | Sotos Syndrome | Gerstmann-Straussler-Scheinker Syndrome | Partington Syndrome | Hereditary Spherocytosis | Congenital Adrenal Hyperplasia 1 | Klinefelter Syndrome | Pneumothorax | Reticular Dysgenesis | Ependymoma | Transthyretin-related Amyloidosis | Non-proliferative Diabetic Retinopathy | Tricho-hepato-enteric Syndrome | Chronic Granulomatous Disease | Goiter | Vici Syndrome | Alopecia | Motor Neuron Diseases | Acute Chest Syndrome | Primary Sclerosing Cholangitis | Peeling Skin Syndrome Type B | DICER1 Syndrome | Erysipelas | Torticollis | Waardenburg Syndrome Type 1 | Ectopia Lentis, Isolated, Autosomal Recessive | Xeroderma Pigmentosum Variant Type | Hydrops Fetalis | Autosomal Recessive Spastic Paraplegia Type 35 | NDH Syndrome | Schistosomiasis Mansoni | Chronic Thromboembolic Pulmonary Hypertension | Mucolipidosis Type II | Sarcoma, Alveolar Soft Part | Hereditary Multiple Exostoses | Esophagitis | Acute Anterior Uveitis | Coronary Heart Disease | Creatine Deficiency Syndrome Due To AGAT Deficiency | Paternal Uniparental Disomy Of Chromosome 14 | Generalized Epilepsy With Febrile Seizures Plus | Glaucoma, Congenital | LRBA Deficiency | Ataxia-ocular Apraxia 2 | Fibrodysplasia Ossificans Progressiva | Anovulation | Androgen Insensitivity | Dengue Hemorrhagic Fever | Auriculocondylar Syndrome | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Ebstein Anomaly | Neurofibroma, Plexiform | C3 Glomerulopathy | Sulfite Oxidase Deficiency | Megaloblastic Anemia | Enhanced S-cone Syndrome | Genitopatellar Syndrome | Congenital Dyserythropoietic Anemia | Craniofrontonasal Syndrome | Pemphigoid | Primary Progressive Nonfluent Aphasia | Alpha-thalassemia Myelodysplasia Syndrome | Hypocalcemia | Sclerosteosis 2 | Cabezas Syndrome | Celiac Disease | Goldenhar Syndrome | Spondylocostal Dysostosis | Oculocutaneous Albinism Type 2 | Parapsoriasis | Myasthenia | Polycystic Kidney, Autosomal Dominant | Antisynthetase Syndrome | Malonyl-CoA Decarboxylase Deficiency | Lactose Intolerance | Ollier Disease | Epidermodysplasia Verruciformis | Coffin-Lowry Syndrome | Neurotoxicity | Ligneous Conjunctivitis | Glioblastoma | Pulmonary Stenosis | Chromosome 16p11.2 Deletion Syndrome | Charcot-Marie-Tooth Disease Type 4E | Atelosteogenesis Type 2 | Cervicitis | Zygomycosis | Retinal Degeneration | Colitis, Collagenous | Congenital Absence Of Vas Deferens | Generalized Epilepsy And Paroxysmal Dyskinesia | Pseudoexfoliation Syndrome | Spinocerebellar Ataxia Type 21 | Guanidinoacetate Methyltransferase Deficiency | Sickle Cell Anemia | Episodic Ataxia | Meningioma | Ichthyosis | Bone Marrow Necrosis | Thrombosis | Microphthalmia | Neurofibroma | Guillain-Barre Syndrome | Coronary Restenosis | Dystonia Musculorum Deformans | GLUT1 Deficiency Syndrome | Glycogen Storage Disease | Ectodermal Dysplasia | Aphasia | Spinocerebellar Ataxia Type 6 | Erectile Dysfunction | Diabetes Insipidus | Gitelman Syndrome | Bernard-Soulier Syndrome | Pupil Disorders | Amish Infantile Epilepsy Syndrome | Schnyder Crystalline Corneal Dystrophy | Haim-Munk Syndrome | Kearns-Sayre Syndrome | Alexander Disease | Histiocytic Sarcoma | Chorea-acanthocytosis | Proximal Symphalangism | Scleroderma | Dyggve-Melchior-Clausen Disease | Basal Ganglia Disease | Esophageal Adenocarcinoma | Liver Failure | Benign Hereditary Chorea | Diabetic Macular Edema | Viral Meningitis | Neural Tube Defect | Arthropathy | Multiple Sclerosis, Primary Progressive | Sleep Apnea, Central | Kabuki Syndrome 2 | Cornelia De Lange Syndrome | Pityriasis Rubra Pilaris | Sjogren Syndrome | Pyruvate Dehydrogenase Deficiency | Pure Red Cell Aplasia | Beta-Propeller Protein-associated Neurodegeneration | Dupuytren Disease | Fatty Aldehyde Dehydrogenase Deficiency | Alazami Syndrome | Whipple's Disease | Spondylocarpotarsal Synostosis Syndrome | Cocaine-Related Disorders | Superficial Spreading Melanoma | Hypoplastic Left Heart Syndrome | Lathosterolosis | Stuve-Wiedemann Syndrome | Sezary Syndrome | Gilbert Syndrome | Carpal Tunnel Syndrome | Malnutrition | Nephritis, Interstitial | Seborrheic Dermatitis | PASLI Disease | Rhabdoid Tumor | Alcoholism | Erythema Nodosum | Diffuse Palmoplantar Keratoderma | Pseudomyxoma Peritonei | Camurati-Engelmann Disease | Follicular Dendritic Cell Sarcoma | Ileitis | Bladder Exstrophy | Autism | Gliosarcoma | Thrombophilia | Glaucoma | Plasmacytoma | Succinic Semialdehyde Dehydrogenase Deficiency | Familial Partial Lipodystrophy | Cystitis | Encephalopathy, Hepatic | Glycogen Storage Disease Type 4 | Sarcoma | Epidermolysis Bullosa Simplex, Localized | Von Willebrand Disease | Tyrosinemia Type 1 | Pierson Syndrome | Juvenile Polyposis | Joubert Syndrome 2 | Long QT Syndrome Type 3 | Patent Ductus Arteriosus | Myopathy | Gangliosidosis, GM1 | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Hereditary Neuropathy With Liability To Pressure Palsies | Leber Congenital Amaurosis | Isovaleric Acidemia | Keloid | Infantile Spasm | Congenital Torticollis | Dengue Shock Syndrome | Postaxial Polydactyly | Spondyloarthritis | Hemochromatosis Type 2 | Adenoma, Villous | Pineoblastoma | Krabbe Disease | Coenzyme Q10 Deficiency | Familial Male-limited Precocious Puberty | Angioedema, Acquired | Choriocarcinoma | Papillon-Lefevre Syndrome | 3-hydroxy-3-methylglutaric Aciduria | Tremor | Astrocytoma, Anaplastic | Dysfibrinogenemia | Pyoderma Gangrenosum | Oligospermia | Rash | Pseudo-pseudohypoparathyroidism | Microphthalmia, Syndromic 7 | Galloway-Mowat Syndrome | Blepharo-cheilo-odontic Syndrome | Dysmorphophobia | Neurofibromatosis | Cutaneous Mastocytosis | Kaposiform Hemangioendothelioma | Polycythemia Vera | Cardiomyopathy, Restrictive | Greig Cephalopolysyndactyly Syndrome | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Delayed Sleep Phase Syndrome | Bloom Syndrome | Hypertension, Portal | Borjeson-Forssman-Lehmann Syndrome | Huntington's Disease | Autism Spectrum Disorders | Adrenomyeloneuropathy | Osteogenesis Imperfecta Type V | Double Outlet Right Ventricle | Oculocutaneous Albinism Type 4 | DEND Syndrome | Leiomyosarcoma | Antisocial Personality Disorder | Pulmonary Capillary Hemangiomatosis | Protein S Deficiency | Polycystic Ovary Syndrome | Macular Degeneration | Swine Influenza | Congenital Stationary Night Blindness | Purpura | Nutrition Disorders | Iron Metabolism Disorders | Corneal Dystrophy And Perceptive Deafness | Pearson Syndrome | Pre-eclampsia | Central Pain Syndrome | Malaria, Cerebral | Dysferlinopathy | AIDS | Pneumoconiosis | Conn Syndrome | Aldosteronism | Cryptococcal Meningitis | Ehlers-Danlos Syndrome | Paraganglioma, Carotid Body | Potocki-Shaffer Syndrome | Spinocerebellar Ataxia Type 40 | Long QT Syndrome Type 1 | Adams-Oliver Syndrome | Localized Scleroderma | Exostoses | CEDNIK Syndrome | Neurodegeneration With Brain Iron Accumulation | Intestinal Hypomagnesemia 1 | Carbohydrate Metabolism Disorders | Recurrent Respiratory Papillomatosis | Diabetes Insipidus, Nephrogenic | Carcinoma, Squamous Cell | Plasma Cell Leukemia | Retinal Vasculitis | Emery-Dreifuss Muscular Dystrophy | Norrie Disease | Sialoadenitis | Hypersensitivity | Intracerebral Hemorrhage | Atopic Dermatitis | Prostatitis | Craniopharyngioma | Vestibular Disease | Richter's Syndrome | Tracheal Disorders | Tinea Versicolor | Heavy Chain Disease | Dental Caries | HANAC Syndrome | Gastric Atrophy | Bulimia Nervosa | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Rheumatic Heart Disease | ICF Syndrome | ADNP Syndrome | Early Infantile Epileptic Encephalopathy 28 | Congenital Heart Defects | Oculodentodigital Dysplasia | Muscle Wasting | Tinea | Nestor-Guillermo Progeria Syndrome | Peeling Skin Syndrome, Acral Type | Seizures | Cholecystitis | Growth Hormone Excess