Gliosarcoma

About the Disease
Gliosarcoma, also known as glioblastoma with sarcomatous component, is related to glioma susceptibility 1 and glioblastoma, and has symptoms including headache and seizures. An important gene associated with Gliosarcoma is MSH2 (MutS Homolog 2), and among its related pathways/superpathways are Apoptotic Pathways in Synovial Fibroblasts and ERK Signaling. The drugs Temozolomide and Lomustine have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and t cells, and related phenotypes are Decreased viability and Decreased viability

Common Targets
BCL2L12 | IDH1 | G4851 | SLC7A5 | PIK3CA | FLT4 | FLT1 | G1956 | KDR | FLT3 | RET | CSNK1A1 | APC | MGMT | PTPN11 | CTNNB1 | KIT | ABL1 | G673 | G7157 | DNA-Dependent Protein Kinase (DNA-PK) | G5728 | G1029

Note: If you'd like to get a target analysis report for Gliosarcoma, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Gliosarcoma at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Pulverulent Zonular Cataract | Cystinosis | Hepatitis, Autoimmune | Progressive Familial Intrahepatic Cholestasis Type 3 | Hypercalcemia | Hereditary Sensory And Autonomic Neuropathy | Colitis, Collagenous | Renal Dysplasia | Language Disorders | Hereditary Spherocytosis | Neuroectodermal Tumors, Primitive | Ocular Hypertension | Inborn Errors Of Metabolism | Maternally Inherited Diabetes And Deafness | Wilson's Disease | Osteonecrosis Of The Jaw | Angiosarcoma Of The Breast | Ebstein Anomaly | Harlequin Ichthyosis | Sick Sinus Syndrome | Stickler Syndrome | Adams-Oliver Syndrome | Non-small Cell Lung Cancer | Postpartum Depression | Behcet's Disease | Neurofibrosarcoma | Congenital Myopathy | Primary Pigmented Nodular Adrenocortical Disease | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Cellulitis | Transcobalamin Deficiency | Exocrine Pancreatic Insufficiency | Anosmia, Congenital | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Poikiloderma With Neutropenia | Chronic Lymphocytic Leukemia | Tay-Sachs Disease | Wolfram Syndrome 2 | Usher Syndrome | Actinomycetoma | Campomelic Dysplasia | Vitamin B12 Deficiency | Oligospermia | Peripheral Neuropathy | Lupus Erythematosus | Primary Aldosteronism | Mitochondrial Myopathy | Greig Cephalopolysyndactyly Syndrome | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | PHARC Syndrome | Rotor Syndrome | Gingivitis | Hypertelorism | Temtamy Preaxial Brachydactyly Syndrome | Stomatitis | Sarcoma, Alveolar Soft Part | Warsaw Breakage Syndrome | Asthma, Nocturnal | Silver-Russell Syndrome | Antisynthetase Syndrome | Multicentric Carpotarsal Osteolysis Syndrome | Bulimia Nervosa | Onchocerciasis | Sarcomatoid Carcinoma Of The Lung | D-2-Hydroxyglutaric Aciduria | Impetigo | Apert Syndrome | Neurodevelopmental Disorders | Vascular Calcification | Dengue Hemorrhagic Fever | Spondylometaphyseal Dysplasia | Acne Vulgaris | Charcot-Marie-Tooth Disease, Type 2C | Leukodystrophies | Reticular Dysgenesis | Parapsoriasis | Rett Syndrome | Milk Allergy | Anodontia | Polymyositis | Epidermolysis Bullosa | Purpura | Hepatic Steatosis | Myelitis, Transverse | L-2-Hydroxyglutaric Aciduria | Niemann-Pick Disease, Type A | Lateral Meningocele Syndrome | Alpers Syndrome | Hereditary Spastic Paraplegia | Toxic Epidermal Necrolysis | Pulmonary Sclerosing Hemangioma | Juvenile Polyposis | Congenital Heart Defects | Sorsby Fundus Dystrophy | Temporal Lobe Epilepsy | Non-epidermolytic Palmoplantar Keratoderma | Dysplastic Nevus | Congenital Hemolytic Anemia | Retinopathy Of Prematurity | Colitis, Lymphocytic | Scleroderma, Diffuse | Purpura, Thrombotic Thrombocytopenic | Chronic Enteropathy Associated With SLCO2A1 Gene | Benign Recurrent Intrahepatic Cholestasis 1 | Cryoglobulinemia | Oculopharyngeal Muscular Dystrophy | Pulmonary Stenosis | Ulcerative Colitis | Autosomal Recessive Bestrophinopathy | Fanconi Anemia | Globozoospermia | Galloway-Mowat Syndrome | Central Retinal Artery Occlusion | Impulse Control Disorder | Basal Cell Nevus Syndrome | Congenital Dyserythropoietic Anemia Type 4 | Spinal And Bulbar Muscular Atrophy | IgA Deficiency | Hepatitis B, Chronic | Congenital Aniridia | Multiple System Atrophy | Gastric Atrophy | Exostoses | Congenital Stationary Night Blindness | Cenani-Lenz Syndactyly Syndrome | Prurigo Nodularis | Erectile Dysfunction | Endometrial Hyperplasia | Chylothorax, Congenital | Keratosis, Seborrheic | Mohr-Tranebjaerg Syndrome | Liddle Syndrome | Atelosteogenesis Type 2 | Aceruloplasminemia | Shock, Cardiogenic | Pyloric Stenosis, Infantile Hypertrophic | N-acetylglutamate Synthase Deficiency | Wieacker-Wolff Syndrome | Encephalopathy, Ethylmalonic | Alpha-1 Antitrypsin Deficiency | Twin-to-twin Transfusion Syndrome | Seborrheic Dermatitis | Zygomycosis | Hypercholesterolemia, Familial | Pyoderma Gangrenosum | Diarrhea | Hypoglycemia | Beare-Stevenson Syndrome | Progressive External Ophthalmoplegia | Distal Myopathy | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Galactosemia | Low Tension Glaucoma | Nicotine Addiction | Spinal Cord Diseases | Sickle Cell Disease | Histiocytosis | Asphyxia Neonatorum | Argininosuccinic Aciduria | Bartsocas-Papas Syndrome | Optic Nerve Diseases | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Obsessive-compulsive Disorder | Basal Ganglia Disease | Keratitis | Rash | Blue Rubber Bleb Nevus Syndrome | Encephalopathy | Axenfeld-Rieger Syndrome | Atelosteogenesis Type 1 | Hypersomnia | Epidermal Nevus Syndrome | Avellino Corneal Dystrophy | Synovitis | Osteoglophonic Dysplasia | Hemolytic Uremic Syndrome | Facioscapulohumeral Muscular Dystrophy Type 2 | Borjeson-Forssman-Lehmann Syndrome | B-cell Chronic Lymphocytic Leukemia | Acrodysostosis | Idiopathic Multicentric Castleman Disease | Cat Eye Syndrome | Waardenburg Syndrome Type 2A | Kaposiform Hemangioendothelioma | Myotonia | Congenital Central Hypoventilation Syndrome | Osteoporosis, Postmenopausal | Spinocerebellar Ataxia Type 28 | Carpal Tunnel Syndrome | Ehlers-Danlos Syndrome | Erythropoietic Protoporphyria | Pilomatrix Carcinoma | Fraser Syndrome | Central Pain Syndrome | Pancreatitis | Hyperandrogenemia | Retinitis | Desmosterolosis | Hypertension | Glycogen Storage Disease Type 9 | Hidradenitis | Bruck Syndrome | Nail Disorder, Nonsyndromic Congenital | Leukoencephalopathy, Progressive Multifocal | Goiter | Hemophilia | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Salla Disease | Seasonal Mood Disorder | 5-oxoprolinase Deficiency | Takayasu's Arteritis | Charcot-Marie-Tooth Disease Type 4B1 | Brugada Syndrome 1 | Acute Kidney Injury | Pulmonary Tuberculosis | Spondylocarpotarsal Synostosis Syndrome | Trichorhinophalangeal Syndrome | Waardenburg Syndrome | Paroxysmal Nocturnal Hemoglobinuria | Aneurysm, Abdominal Aortic | Rheumatic Heart Disease | Vitamin A Deficiency | Plasmacytoma | Neurofibromatosis Type 2 | Joubert Syndrome 2 | Macular Degeneration | Osteoarthritis | Chorea | Ganglioglioma | Lymphoma, Follicular | Central Core Disease | Dermatitis Herpetiformis | Cholangiocarcinoma | DRESS Syndrome | Hypopigmentation | Meesmann Corneal Dystrophy | Basan Syndrome | Placenta Previa | Vasculitis | Fabry's Disease | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Hypotension, Orthostatic | Corneal Neovascularization | Goldenhar Syndrome | Fibronectin Glomerulopathy | Erythromelalgia | Hyperammonemia | Cardiofaciocutaneous Syndrome | Celiac Disease | Epilepsy, Generalized | Sclerocornea | Meningeal Melanocytoma | Discoid Lupus Erythematosus | Brenner Tumor | Colon Adenoma | Blastoma, Pleuropulmonary | Holt-Oram Syndrome | Congenital Ichthyosiform Erythroderma | Hyperinsulinemia | Diabetes Insipidus, Nephrogenic | Niemann-Pick Disease | Autosomal Recessive Spastic Paraplegia Type 75 | Cervicitis | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Galactosialidosis | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Hyperbilirubinemia | Congenital Torticollis | Snyder-Robinson Syndrome | Spinocerebellar Ataxia Type 31 | Split Hand-foot Malformation | Ectodermal Dysplasia | Fanconi Syndrome | Anti-glomerular Basement Membrane Disease | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | NDH Syndrome | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Porphyria Cutanea Tarda | Creutzfeldt-Jakob Disease | Heart Septal Defects | Melanoma, Uveal | DICER1 Syndrome | Chronic Myeloid Leukemia | Esotropia | Anxiety Disorders | Melanoma | Homocystinuria | Hyperglycemia | Iron Metabolism Disorders | Situs Inversus | Glanzmann Thrombasthenia | Neurofibromatosis | Left Ventricular Noncompaction | Retinitis Pigmentosa | Atopy | Mitochondrial DNA Depletion Syndrome | Neurofibromatosis-Noonan Syndrome | Lysosomal Acid Lipase Deficiency | Mountain Sickness | Jalili Syndrome | Donnai-Barrow Syndrome | Antley-Bixler Syndrome | Alveolar Capillary Dysplasia | Renal Hypomagnesemia 3 | Tietze Syndrome | Scleritis | Congenital Nystagmus | Benign Hereditary Chorea | Rhabdomyosarcoma | Acrodermatitis | Ellis-Van Creveld Syndrome | Chylomicron Retention Disease | Alkaptonuria | Hyperlipidemia Type V | Poirier-Bienvenu Neurodevelopmental Syndrome | Vitiligo | Wolcott-Rallison Syndrome | Coffin-Siris Syndrome | AIDS | Lewy Body Dementia | Vitreoretinal Degeneration, Snowflake Type | Neural Tube Defect | Osteogenesis Imperfecta Type V | Postaxial Polydactyly | Crisponi Syndrome | IgA Nephropathy | Mitochondrial Cytopathy | Moyamoya Disease | Splenomegaly | Androgen Insensitivity | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Cone Dystrophy | DNA Ligase IV Deficiency | Spondyloperipheral Dysplasia | Jaundice, Obstructive | Hereditary Folate Malabsorption | Ileitis | Inflammatory Joint Disease | Hereditary Coproporphyria | Meconium Ileus | Obesity | Nemaline Myopathy | Chronic Leukemia | Colitis | Burn-McKeown Syndrome | Familial Male-limited Precocious Puberty | Pyelonephritis | Malonyl-CoA Decarboxylase Deficiency | Neurocysticercosis | Carotid Artery Disease | Epilepsy | Ophthalmia, Sympathetic | Blepharospasm | Obesity, Morbid | Schizoaffective Disorder | Aphasia | Hyperuricemia | Charcot-Marie-Tooth Disease Type 2D | Cutaneous T-cell Lymphoma | Heroin Dependence | Gliosarcoma | Congenital Fiber-type Disproportion Myopathy | Mastitis | Chronic Inflammatory Demyelinating Polyneuropathy | Glutathione Synthetase Deficiency | Microtia | Huntington's Disease-like 2 | Varices | Methylmalonic Acidemia | Phosphoglycerate Dehydrogenase Deficiency | Myoclonus-dystonia Syndrome | Delirium | Systemic Mastocytosis | Tularemia | Norrie Disease | Hyperthermia, Malignant | Coloboma | Bardet-Biedl Syndrome | Spondylo-ocular Syndrome | Sandhoff Disease | Encephalitis | Charcot-Marie-Tooth Disease Type 3 | Fowler's Syndrome | Hyperparathyroidism, Secondary | Low Phospholipid Associated Cholelithiasis | Heart Failure | Neurodermatitis | Compartment Syndrome | Aneurysm, Thoracic Aortic | Microphthalmia | Thin Basement Membrane Disease | Prolidase Deficiency | Autoimmune Disease | Stroke | Neuromuscular Disorders | Non-Hodgkin Lymphoma | Tinea | Adenomyosis | Pleurisy | Blau Syndrome