Iron Metabolism Disorders

About the Disease
Iron Metabolism Disease, also known as iron deficiency, is related to neurodegeneration with brain iron accumulation 1 and neurodegeneration with brain iron accumulation 3. An important gene associated with Iron Metabolism Disease is HFE (Homeostatic Iron Regulator), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Glucose / Energy Metabolism. The drugs Dopamine and Levoleucovorin have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and liver, and related phenotypes are homeostasis/metabolism and liver/biliary system

Common Targets
HAMP | NFU1 | FTL | SLC40A1 | SLC11A2

Note: If you'd like to get a target analysis report for Iron Metabolism Disorders, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Iron Metabolism Disorders at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Periodontitis | Osteomyelitis | Uremia | Craniometaphyseal Dysplasia | Fowler's Syndrome | Common Cold | Cystinosis | Reticular Dysgenesis | Corneal Dystrophy | 3-M Syndrome | Craniofrontonasal Syndrome | Early Infantile Epileptic Encephalopathy 28 | Thin Basement Membrane Disease | Kaposiform Hemangioendothelioma | Thyroiditis, Autoimmune | Chronic Beryllium Disease | Pontocerebellar Hypoplasia | Cholesteryl Ester Storage Disease | Pineoblastoma | Kallmann Syndrome | Coronary Heart Disease | Ataxia-ocular Apraxia 2 | Cold-induced Sweating Syndrome | Rheumatic Heart Disease | Schindler Disease | Retinal Coloboma | Rotor Syndrome | Acromesomelic Dysplasia | Anorchia | Liebenberg Syndrome | Heterotopic Ossification | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Polycythemia | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Alpha-1 Antitrypsin Deficiency | Amyloidosis | Beare-Stevenson Syndrome | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Adrenoleukodystrophy, X-linked | Major Depression | Neurofibromatosis Type 2 | Rothmund-Thomson Syndrome | Adenomatoid Tumor | Keratocystic Odontogenic Tumor | Geleophysic Dysplasia | Angiodysplasia | Multiple Hamartoma Syndrome | Hemolytic Anemia | Hereditary Coproporphyria | Tangier Disease | Peroxisomal Disorder | VACTERL Association | Renal Oncocytoma | Trichotillomania | Waldenstrom Macroglobulinemia | Cysticercosis | Pyruvate Kinase Deficiency | Nephronophthisis | Hypotrichosis Simplex | Neurofibromatosis | Thyroid Hormone Resistance | Paroxysmal Kinesigenic Dyskinesia | Tibial Muscular Dystrophy | Primary Aldosteronism | Disseminated Intravascular Coagulation | Parkinsonism | Nephropathy | Dent Disease | Ocular Albinism Type 1 | Hemoglobinopathies | Opisthorchiasis | Tyrosine Hydroxylase Deficiency | Pierpont Syndrome | Sickle Cell Anemia | Auriculocondylar Syndrome | Premature Ejaculation | Amenorrhea | Methemoglobinemia Type IV | Mosaic Variegated Aneuploidy Syndrome 2 | Acne | Motor Neuron Diseases | Vitamin A Deficiency | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Progressive Myoclonic Epilepsy | Angioimmunoblastic T-cell Lymphoma | Gigantism | Mood Disorder | Multiple System Atrophy | Anencephaly | Basal Ganglia Disease | Poretti-Boltshauser Syndrome | Skin Papilloma | Meningococcal Meningitis | Combined Deficiency Of Factor V And Factor VIII | Nasodigitoacoustic Syndrome | Primary Progressive Aphasia | Myelofibrosis | Primary Familial Brain Calcification | Erythema Nodosum | Neurocutaneous Melanocytosis | C3 Glomerulonephritis | Spinocerebellar Ataxia Type 10 | Mountain Sickness | LRBA Deficiency | Postpartum Depression | Borderline Personality Disorder | Niemann-Pick Disease, Type A | Spinocerebellar Ataxia Type 12 | Erythrokeratodermia Variabilis | Adenoma, Pleomorphic | Osteogenesis Imperfecta Type V | Esophageal Motility Disorders | IgA Nephropathy | Meningeal Melanocytoma | Anterior Segment Dysgenesis | Encephalitis, Tick-borne | Benign Familial Neonatal Convulsions | Dyggve-Melchior-Clausen Disease | Optic Neuropathy | Arterial Tortuosity Syndrome | Cholelithiasis | Salla Disease | Mucolipidosis Type IV | Corneal Dystrophies, Hereditary | Autosomal Recessive Spastic Paraplegia Type 75 | Infantile Spasm | Myasthenia | Kashin-Beck Disease | Premenstrual Syndrome | REM Sleep Behavior Disorder | Nephrocalcinosis | Periodic Limb Movement Disorder | Myasthenia Gravis | Stargardt Disease | Desmosterolosis | Keloid | Cerebrovascular Disorders | CDKL5 Deficiency Disorder | Hepatitis, Alcoholic | Reflex Epilepsy | Scapuloperoneal Myopathy, X-linked Dominant | Hypoproteinemia, Hypercatabolic | Galactosemia | Analgesia | Binge Eating Disorder | Sialoadenitis | Vogt-Koyanagi-Harada Syndrome | Sitosterolemia | Anosmia, Congenital | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Congenital Mirror Movements | Angiomyolipoma | Gaucher Disease | Guillain-Barre Syndrome | Waardenburg Syndrome | Huntington's Disease | Pyruvate Carboxylase Deficiency Disease | Sarcoma, Endometrial Stromal | Angioedema | Vitamin K Deficiency | Patent Ductus Arteriosus | Metatropic Dysplasia | Chondrodysplasia Punctata 2, X-linked Dominant | Allergic Contact Dermatitis | Transient Bullous Dermolysis Of The Newborn | Blue Rubber Bleb Nevus Syndrome | Agnathia-Otocephaly Complex | Immunoproliferative Disorders | Dysequilibrium Syndrome | Pseudoachondroplasia | Prolidase Deficiency | Lymphoma, AIDS-related | Schistosomiasis | Nicolaides-Baraitser Syndrome | Limb Girdle Muscular Dystrophy | Corneal Edema | Erdheim-Chester Disease | Angelman Syndrome | Pseudo-pseudohypoparathyroidism | Cerebellar Ataxia, Cayman Type | Zellweger Syndrome | Hyperlipidemia, Familial Combined | Meckel-Gruber Syndrome | Prurigo Nodularis | Addison Disease | Acute Myeloid Leukemia | Cystinuria | Early Infantile Epileptic Encephalopathy | Sandhoff Disease | Farber Disease | Glycogen Storage Disease Type 0 | Bartter Syndrome | Thrombosis | Parvovirus B19 Infection | Arthritis, Gouty | Presbycusis | Chitayat Syndrome | Epilepsy, Generalized | Cockayne Syndrome | Cousin Syndrome | Pupil Disorders | Hereditary Spastic Paraplegia | Otitis Externa | Hypertrophy | Raine Syndrome | Congenital Nystagmus | Cramp Fasciculation Syndrome | Cryptococcal Meningitis | Anxiety Disorders | Keratoconjunctivitis | Hypohidrotic Ectodermal Dysplasia, X-linked | Myelitis | Hamartoma | Retinal Telangiectasia | Extramammary Paget's Disease | CHOPS Syndrome | Sporadic Inclusion Body Myositis | Diastrophic Dysplasia | Hemolytic Uremic Syndrome | Epicondylitis | Cholangiocarcinoma | Carbonic Anhydrase VA Deficiency | Chronic Myeloid Leukemia | Recurrent Respiratory Papillomatosis | Thyroid Dyshormonogenesis | Zygomycosis | Urea Cycle Disorder | Keratitis-ichthyosis-deafness Syndrome | Hypolipoproteinemia | Bruck Syndrome | Intermittent Claudication | Fibrosarcoma | Hidradenitis Suppurativa | Schwannomatosis | Hypotonia-cystinuria Syndrome | Retinitis Pigmentosa 3 | Charcot-Marie-Tooth Disease Type 2T | Leukoplakia, Oral | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Cardiac Arrest | Demyelinating Diseases | Primary Hyperoxaluria Type 1 | Hidradenitis | Neurofibroma | Thyroid Dysgenesis | Adenylosuccinate Lyase Deficiency | Autonomic Nervous System Disorders | Dementia | Angiosarcoma | Cheilitis | Headache | Liddle Syndrome | Basal Cell Nevus Syndrome | Epidermolytic Hyperkeratosis | Glutaric Aciduria Type 3 | Triphalangeal Thumb-polysyndactyly Syndrome | Borjeson-Forssman-Lehmann Syndrome | Renal Tubular Acidosis | Spondylolisthesis | Saul-Wilson Syndrome | Primary Sclerosing Cholangitis | Fuchs Heterochromic Iridocyclitis | Renal Hypouricemia | Chudley-McCullough Syndrome | Nijmegen Breakage Syndrome | Enlarged Vestibular Aqueduct | Inflammatory Linear Verrucous Epidermal Nevus | Glanzmann Thrombasthenia | Milk Allergy | Pyoderma Gangrenosum | Leri-Weill Dyschondrosteosis | Carey-Fineman-Ziter Syndrome | Tetraplegia | Plasma Cell Dyscrasia | Spinal Cord Diseases | Primary Carnitine Deficiency | Bicuspid Aortic Valve | Hodgkin Lymphoma | Distal Myopathy | Erythematotelangiectatic Rosacea | Tendinopathy | Holoprosencephaly | Donnai-Barrow Syndrome | Patent Foramen Ovale | Lymphoproliferative Disorders | Blastoma, Pleuropulmonary | Myotonia | Carpal Tunnel Syndrome | Trismus-pseudocamptodactyly Syndrome | Neurocutaneous Syndromes | Hyperthyroidism | Empyema | Trigonocephaly | Proteasome-associated Autoinflammatory Syndrome 2 | Microcephaly, Seizures, And Developmental Delay | Cannabis Abuse | Metachondromatosis | Endometriosis | Osteopathia Striata With Cranial Sclerosis | Hypercalciuria | Cohen Syndrome | Acquired Partial Lipodystrophy | Neuroendocrine Cancer | Hereditary Xerocytosis | Spasticity | Spondylo-megaepiphyseal-metaphyseal Dysplasia | T-cell Prolymphocytic Leukemia | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Hepatoblastoma | Congestive Heart Failure | Uterine Leiomyoma | Dysplastic Nevus | Gerstmann-Straussler-Scheinker Syndrome | Impulse Control Disorder | Congenital Stationary Night Blindness | Autosomal Recessive Spastic Paraplegia Type 54 | Chylomicron Retention Disease | L-2-Hydroxyglutaric Aciduria | Cholera | Goiter, Nodular | Cardiofaciocutaneous Syndrome | Persistent Fetal Circulation | MELAS Syndrome | Pemphigus Vulgaris | Globozoospermia | Photosensitivity | Camptocormia | Subcortical Band Heterotopia | Esophagitis, Eosinophilic | Acute Generalized Exanthematous Pustulosis | Renal Dysplasia | Pheochromocytoma | Beta-Propeller Protein-associated Neurodegeneration | Perry Syndrome | Tardive Dyskinesia | Hypertension | Glioblastoma Multiforme | Cole-Carpenter Syndrome | Tendinitis | Obsessive-compulsive Disorder | Atherosclerosis | Familial Hyperaldosteronism | DNA Ligase IV Deficiency | Porphyria Cutanea Tarda | Congenital Disorders Of Glycosylation | Angioedema, Acquired | Renal Tubular Dysgenesis | Giant Cell Arteritis | Chordoid Glioma | Gallstones | Bare Lymphocyte Syndrome | Trichothiodystrophy | Language Disorders | Goldenhar Syndrome | Meier-Gorlin Syndrome | Epidermolytic Ichthyosis, Annular | D-2-Hydroxyglutaric Aciduria | Splenomegaly | Infantile Nephropathic Cystinosis | Torticollis | Aphasia | Seasonal Mood Disorder | Familial Partial Lipodystrophy | Acute Coronary Syndrome | Neuroleptic Malignant Syndrome | Leukocyte Adhesion Deficiency | Vertigo | Esophageal Adenocarcinoma | Ulcerative Colitis | Batten Disease | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Sjogren Syndrome | Amyotrophic Lateral Sclerosis | Usher Syndrome | Acanthosis Nigricans | Congenital Disorders Of Glycosylation Type II | Skin Carcinoma | Strabismus | Proctitis | Hypobetalipoproteinemias | Alpha-mannosidosis | Oguchi Disease-2 | Glycogen Storage Disease Type 3 | Chondrosarcoma | Potocki-Shaffer Syndrome | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Optic Atrophy 2 | Bietti Crystalline Dystrophy | Peters-plus Syndrome | Dystonia | Nemaline Myopathy | Pancreatitis, Chronic | HELLP Syndrome | Macular Corneal Dystrophy Type 1 | Polycythemia Vera | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Central Retinal Artery Occlusion | Teratozoospermia | Angiosarcoma Of The Breast