Nephronophthisis

About the Disease
Juvenile Nephronophthisis, also known as nephronophthisis, familial juvenile, is related to nephronophthisis 1 and arima syndrome, and has symptoms including polyuria and polydipsia. An important gene associated with Juvenile Nephronophthisis is NPHP1 (Nephrocystin 1), and among its related pathways/superpathways are Organelle biogenesis and maintenance and Ciliary landscape. The drug Coal tar has been mentioned in the context of this disorder. Affiliated tissues include kidney, liver and retina, and related phenotypes are renal/urinary system and cellular

Common Targets
OFD1 | INVS | TTC21B | SCLT1 | BBS2 | CEP83 | NPHP4 | ANKS6 | TMEM67 | BBS12 | IQCB1 | ADAMTS9 | PKHD1 | WDR19 | ALMS1 | NPHP3 | DYNC2H1 | UMOD | IFT122 | WDR35 | DCDC2 | SDCCAG8 | CEP164 | MAPKBP1 | MKKS | BBS4 | CC2D2A | BBS1 | IFT140 | HNF1B | BBS10 | NPHP1

Note: If you'd like to get a target analysis report for Nephronophthisis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Nephronophthisis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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