Disease

Nephronophthisis

About the Disease
Juvenile Nephronophthisis, also known as nephronophthisis, familial juvenile, is related to nephronophthisis 1 and arima syndrome, and has symptoms including polyuria and polydipsia. An important gene associated with Juvenile Nephronophthisis is NPHP1 (Nephrocystin 1), and among its related pathways/superpathways are Organelle biogenesis and maintenance and Ciliary landscape. The drug Coal tar has been mentioned in the context of this disorder. Affiliated tissues include kidney, liver and retina, and related phenotypes are renal/urinary system and cellular

Common Targets
OFD1 | INVS | TTC21B | SCLT1 | BBS2 | CEP83 | NPHP4 | ANKS6 | TMEM67 | BBS12 | IQCB1 | ADAMTS9 | PKHD1 | WDR19 | ALMS1 | NPHP3 | DYNC2H1 | UMOD | IFT122 | WDR35 | DCDC2 | SDCCAG8 | CEP164 | MAPKBP1 | MKKS | BBS4 | CC2D2A | BBS1 | IFT140 | HNF1B | BBS10 | NPHP1

疾病靶点研报
Nephronophthisis

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