Hepatic Veno-occlusive Disease

About the Disease
Hepatic Veno-Occlusive Disease, also known as sinusoidal obstruction syndrome, is related to pulmonary edema and budd-chiari syndrome. An important gene associated with Hepatic Veno-Occlusive Disease is SERPINC1 (Serpin Family C Member 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Signaling by Receptor Tyrosine Kinases. The drugs Inotuzumab ozogamicin and Antineoplastic Agents, Immunological have been mentioned in the context of this disorder. Affiliated tissues include liver, bone marrow and endothelial, and related phenotypes are hepatomegaly and renal insufficiency

Common Targets
GSTT1 | XDH | SP110 | PLAT | CYP1A2 | MTHFR | UGT2B17 | ABCC1 | MSH2

Note: If you'd like to get a target analysis report for Hepatic Veno-occlusive Disease, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Hepatic Veno-occlusive Disease at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Intestinal Pseudo-obstruction | Congenital Absence Of Vas Deferens | Tay-Sachs Disease | Papillorenal Syndrome | Schamberg Disease | Dupuytren Disease | Yellow Fever | Marshall-Smith Syndrome | Retinitis Pigmentosa 3 | Galactosialidosis | Glutaric Aciduria Type 3 | Hypermethioninemia | FG Syndrome | Asphyxia Neonatorum | Adams-Oliver Syndrome | Cholecystitis | Congenital Dyserythropoietic Anemia Type 4 | Dyskeratosis Congenita | Cherubism | Cabezas Syndrome | Parkinsonism | Shprintzen-Goldberg Syndrome | McKusick Type Metaphyseal Chondrodysplasia | Exotropia | Familial Hypobetalipoproteinemia | Alpers Syndrome | Infantile Nephropathic Cystinosis | Extramammary Paget's Disease | Pancreatitis, Chronic | Optic Nerve Diseases | Familial Exudative Vitreoretinopathy | Nephrocalcinosis | Primary Cutaneous Amyloidosis | Ameloblastic Carcinoma | Ellis-Van Creveld Syndrome | Keratoconus | Keratosis, Seborrheic | Hypotrichosis | Mabry Syndrome | Keratoacanthoma | Vici Syndrome | Megalencephaly | Incontinentia Pigmenti | Angioedema, Acquired | Chronic Idiopathic Myelofibrosis | Angiodysplasia | Cornelia De Lange Syndrome | Anorectal Malformations | Amyloidosis | Lymphangioma | Ocular Hypertension | Hyperbilirubinemia | Premature Ejaculation | Waardenburg Syndrome Type 4 | Postaxial Polydactyly | Growth Hormone Excess | Primary Erythromelalgia | Pyruvate Carboxylase Deficiency Disease | Still Disease | Walker-Warburg Syndrome | Thin Basement Membrane Disease | Exfoliative Dermatitis | Congenital Aniridia | Neurocysticercosis | Jawad Syndrome | Neuroblastoma | Acral Lentiginous Melanoma | Primary Ovarian Insufficiency | Ganglioneuroma | Antithrombin III Deficiency | Hypertrophy | Chylothorax, Congenital | Chromosome 8q21.11 Deletion Syndrome | Familial Mediterranean Fever | Hypotrichosis Simplex | Charcot-Marie-Tooth Disease, Type 2C | Spondylo-ocular Syndrome | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Kawasaki Disease | Hypopituitarism | Stromal Corneal Dystrophy | Urticaria | COACH Syndrome | Pernicious Anemia | Myelomeningocele | Thrombosis | Liddle Syndrome | Diffuse Palmoplantar Keratoderma | Mandibuloacral Dysplasia With Type A Lipodystrophy | Tracheal Disorders | Cole-Carpenter Syndrome | Tendinitis | Zimmermann-Laband Syndrome | Saethre-Chotzen Syndrome | Congenital Stationary Night Blindness | Withdrawal Syndrome | Familial Male-limited Precocious Puberty | Thrombophilia | Hereditary Elliptocytosis | Cardiofaciocutaneous Syndrome | Erythematotelangiectatic Rosacea | Prader-Willi Syndrome | Shock, Cardiogenic | Congenital Afibrinogenemia | Oculocutaneous Albinism | Erythromelalgia | Idiopathic Multicentric Castleman Disease | Epidermolytic Hyperkeratosis | Cerebrotendinous Xanthomatosis | Myelitis, Transverse | Hydrocephalus, Normal Pressure | Gnathodiaphyseal Dysplasia | Vitamin K Deficiency | Usher Syndrome | Peroxisomal Disorder | Progressive Familial Intrahepatic Cholestasis Type 3 | Congenital Mirror Movements | Goldenhar Syndrome | Galactosemia | Usher Syndrome Type IIC | Pseudohermaphroditism | Gyrate Atrophy Of The Choroid And Retina | Mitochondrial DNA Depletion Syndrome 13 | Primary Aldosteronism | Glutaric Aciduria Type 2 | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Chronic Myelomonocytic Leukemia | Pilomatrix Carcinoma | Carcinoma, Small Cell | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Bethlem Myopathy | Isobutyryl-CoA Dehydrogenase Deficiency | Angiosarcoma Of The Breast | Stroke, Hemorrhagic | Gastrointestinal Disorders | Papilledema | Metachromatic Leukodystrophy | Epidermolysis Bullosa | Small Lymphocytic Lymphoma | Carbamoyl Phosphate Synthetase I Deficiency | Xeroderma Pigmentosum | Osteopetrosis | Bernard-Soulier Syndrome | Blue Rubber Bleb Nevus Syndrome | Oligospermia | Purpura, Thrombotic Thrombocytopenic | DiGeorge Syndrome | Double Outlet Right Ventricle | Cryptococcal Meningitis | Glycogen Storage Disease Type 1b | Blepharitis | Hydrocephalus | Hypokalemia | Vogt-Koyanagi-Harada Syndrome | Craniolenticulosutural Dysplasia | Distal Myopathy 2 | Cutaneous T-cell Lymphoma | Microvillus Inclusion Disease | Campomelic Dysplasia | Frank-ter Haar Syndrome | Hepatic Adenomatosis | Multiple Hamartoma Syndrome | Carcinoid Tumor | Tinea Versicolor | Osteoglophonic Dysplasia | Encephalopathy, Hepatic | Dementia | Glycogen Storage Disease | Postpoliomyelitis Syndrome | Lewy Body Dementia | Allan-Herndon-Dudley Syndrome | Carney-Stratakis Syndrome | C3 Glomerulonephritis | Menkes Disease | Spinocerebellar Ataxia | Cannabis Abuse | Renal Hypouricemia | Citrullinemia | Bronchiolitis | Fibrosarcoma | Gastroschisis | Eosinophilia | Giant Axonal Neuropathy | Acute Lymphocytic Leukemia | ACTH-independent Macronodular Adrenal Hyperplasia | Prune Belly Syndrome | Osteogenesis Imperfecta Type V | Paroxysmal Nocturnal Hemoglobinuria | Mohr-Tranebjaerg Syndrome | Schnitzler Syndrome | Pityriasis Rubra Pilaris | Constipation | Dyslipidemia | Corticobasal Syndrome | Cancer, Kidney | Headache | Agnathia-Otocephaly Complex | Hypertension, Renal | Pelvic Inflammatory Disease | Liver Diseases | Corneal Edema | Borderline Personality Disorder | Mixed Connective Tissue Disease | Neurodegeneration With Brain Iron Accumulation | Osteochondrosis | Epilepsy, Generalized | Lupus Erythematosus | Cardiomyopathy, Hypertrophic | X-linked Myotubular Myopathy | Cerebral Amyloid Angiopathy | Geleophysic Dysplasia | Non-bullous Congenital Ichthyosiform Erythroderma | Agammaglobulinemia | Hepatoblastoma | VEXAS Syndrome | Neurofibrosarcoma | Angioimmunoblastic T-cell Lymphoma | Diabetes Insipidus, Nephrogenic | Neurogenic Bladder | Myoclonic Epilepsy With Ragged Red Fibers | Rhabdomyosarcoma, Alveolar | Arteriosclerosis | Vertigo | Rhizomelic Chondrodysplasia Punctata | Hyperferritinemia-cataract Syndrome | Speech Disorders | Huntington's Disease-like 2 | Nicolaides-Baraitser Syndrome | Ischemia | Occipital Neuralgia | Influenza | Hypogonadism | Plasma Cell Dyscrasia | Hypertension, Pulmonary | Omenn Syndrome | Neurofibroma, Plexiform | Pitt-Hopkins Syndrome | Raine Syndrome | Systemic Lupus Erythematosus | Neuromyelitis Optica | Cat Eye Syndrome | Usher Syndrome Type III | Pfeiffer Syndrome | Fabry's Disease | Aneurysm, Thoracic Aortic | Meningitis | Inflammatory Bowel Disease | Woodhouse-Sakati Syndrome | Familial Dysautonomia | Sick Sinus Syndrome | Fukuyama Congenital Muscular Dystrophy | Ebstein Anomaly | Congenital Dysfibrinogenemia | Non-epidermolytic Palmoplantar Keratoderma | Familial Digital Arthropathy-brachydactyly | Nasodigitoacoustic Syndrome | Malaria, Cerebral | 3-hydroxy-3-methylglutaric Aciduria | Thrombotic Microangiopathy | Glycogen Storage Disease Type 0 | High Molecular Weight Kininogen Deficiency | Saul-Wilson Syndrome | Ichthyosis Hystrix, Curth-Macklin Type | Choriocarcinoma | Ureteropelvic Junction Obstruction | Cenani-Lenz Syndactyly Syndrome | Intestinal Tuberculosis | Polymicrogyria | Anthrax | Mucolipidosis Type II | Hypertension, Renovascular | Nevus | Colitis, Microscopic | Polycystic Liver | Pelizaeus-Merzbacher Disease | Hereditary Hemorrhagic Telangiectasia | Hereditary Inclusion Body Myopathy | Myofibrillar Myopathy | Renal Failure | Hyperinsulinemic Hypoglycemia | Amyotrophic Lateral Sclerosis, Juvenile | Relapsing Polychondritis | Blepharophimosis Syndrome | Oguchi Disease-2 | Optic Nerve Hypoplasia, Bilateral | Cutaneous Lupus Erythematosus | Vascular Cognitive Impairment | Astrocytoma, Anaplastic | Kashin-Beck Disease | Glycogen Storage Disease Type 1a | Juvenile Polyposis | Veno-occlusive Disease | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Autosomal Recessive Congenital Ichthyosis | Hamartoma | Maternally Inherited Diabetes And Deafness | Sertoli Cell-only Syndrome | 3-methylcrotonyl-CoA Carboxylase Deficiency | Insulin Resistance | Amebiasis | Disseminated Intravascular Coagulation | Dysmorphophobia | Graves Disease | Heimler Syndrome | Barakat Syndrome | Chanarin-Dorfman Syndrome | Hypersomnia | Sulfite Oxidase Deficiency | Leri Pleonosteosis | Pupil Disorders | Hypercholesterolemia | Sotos Syndrome | Weill-Marchesani Syndrome | Lymphoma Lymphoblastic | Zellweger Syndrome | Spinocerebellar Ataxia Type 40 | Inflammatory Myopathy | Meesmann Corneal Dystrophy | Diabetic Nephropathy | Hypertelorism | Cystinuria | H Syndrome | Rhabdomyosarcoma | Pneumonia, Bacterial | Sialoadenitis | Heart Failure | Cartilage Disorders | Neuromuscular Disorders | Pancreatitis | Language Disorders | Crisponi Syndrome | Hypercalcemia | Congenital Fiber-type Disproportion Myopathy | Melanocytic Nevus | Von Hippel-Lindau Disease | Pompe Disease | Leukocyte Adhesion Deficiency | Conduct Disorder | Hereditary Mixed Polyposis Syndrome | Non-Hodgkin Lymphoma | Hemolytic Anemia | Congenital Primary Aphakia | Anorchia | Kohlschutter-Tonz Syndrome | Localized Scleroderma | Myeloid Leukemia | Synovitis | Plasma Cell Leukemia | Cerebral Cavernous Malformations | Diabetes | Pseudohypoaldosteronism | Glioblastoma Multiforme | Takotsubo Cardiomyopathy | Multiple Epiphyseal Dysplasia | Guanidinoacetate Methyltransferase Deficiency | Dysferlinopathy | Oligoasthenoteratozoospermia | Portal Vein Thrombosis | Menetrier Disease | Neurofibroma | Multiple Sclerosis, Relapsing-remitting | Traboulsi Syndrome | Parkinson's Disease | Heterotopic Ossification | Nephropathy | Alzheimer Disease, Late Onset | Pituitary Dwarfism | Smith-Kingsmore Syndrome | Paternal Uniparental Disomy Of Chromosome 14 | Acrocallosal Syndrome | Proximal Symphalangism | Spinocerebellar Ataxia Type 7 | Leukemia | Hernia, Inguinal | Brenner Tumor | Kindler Syndrome | Brugada Syndrome 1 | Wolff-Parkinson-White Syndrome | Keratitis | Hodgkin Lymphoma | Glomerulonephritis, Membranous | Heart Block | Medulloblastoma | Kaposiform Hemangioendothelioma | Cold-induced Sweating Syndrome | Sezary Syndrome | Schwannomatosis | Borjeson-Forssman-Lehmann Syndrome | Asthma, Nocturnal | Anti-NMDA Receptor Encephalitis | Benign Familial Pemphigus | Chronic Enteropathy Associated With SLCO2A1 Gene | Takenouchi-Kosaki Syndrome | Schizencephaly | Basal Ganglia Disease, Biotin-responsive | Dysplastic Nevus | Down Syndrome | Osteomalacia | Intestinal Hypomagnesemia 1 | Onchocerciasis