Hepatic Veno-occlusive Disease

About the Disease
Hepatic Veno-Occlusive Disease, also known as sinusoidal obstruction syndrome, is related to pulmonary edema and budd-chiari syndrome. An important gene associated with Hepatic Veno-Occlusive Disease is SERPINC1 (Serpin Family C Member 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Signaling by Receptor Tyrosine Kinases. The drugs Inotuzumab ozogamicin and Antineoplastic Agents, Immunological have been mentioned in the context of this disorder. Affiliated tissues include liver, bone marrow and endothelial, and related phenotypes are hepatomegaly and renal insufficiency

Common Targets
GSTT1 | XDH | SP110 | PLAT | CYP1A2 | MTHFR | UGT2B17 | ABCC1 | MSH2

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