Spinal Muscular Atrophy Type 3

About the Disease
Spinal Muscular Atrophy, Type Iii, also known as sma3, is related to spinal muscular atrophy and progressive muscular atrophy, and has symptoms including muscle cramp and tremor of hands. An important gene associated with Spinal Muscular Atrophy, Type Iii is SMN1 (Survival Of Motor Neuron 1, Telomeric), and among its related pathways/superpathways is SARS-CoV-2 modulates host translation machinery. The drugs Risdiplam and Antibodies, Monoclonal have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and tongue, and related phenotypes are proximal lower limb amyotrophy and pelvic girdle muscle weakness

Common Targets
Survival of motor neuron (SMN) complex | CLCN1 | MSTN | SMN1 | SMN2 | Potassium Channels (nonspecified subtype)

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