Hyperprolactinemia

About the Disease
Hyperprolactinemia, also known as chiari-frommel syndrome, is related to galactorrhea and pituitary tumors. An important gene associated with Hyperprolactinemia is PRLR (Prolactin Receptor), and among its related pathways/superpathways are TGF-Beta Pathway and GPCR downstream signalling. The drugs Risperidone and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include pituitary, ovary and bone, and related phenotypes are galactorrhea and oligomenorrhea

Common Targets
HTR3A | BDNF | G207 | CYP2D6 | DRD4 | MAOA | DRD2 | ANKK1 | HTR1A | HTR2B | Prolactin receptor (isoform 1) | GSK3B | PRL | DRD1 | TPH2 | HTR3B | Dopamine receptor (nonspecified subtype) | TPH1 | G5243 | HTR6 | PRLR | HTR1B | HTR2A | 5-Hydroxytryptamine Receptor (nonspecified subtype) | HTR2C | DRD3 | SLC6A3 | MAOB

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