Sleep Apnea

About the Disease
Sleep Apnea, also known as sleep apnea syndromes, is related to central sleep apnea and obesity-hypoventilation syndrome, and has symptoms including apnea, back pain and cheyne-stokes respiration. An important gene associated with Sleep Apnea is AHDC1 (AT-Hook DNA Binding Motif Containing 1), and among its related pathways/superpathways are Signal Transduction and p70S6K Signaling. The drugs Montelukast and Opium have been mentioned in the context of this disorder. Affiliated tissues include heart, lung and tongue, and related phenotypes are homeostasis/metabolism and nervous system

Common Targets
HRH3 | Na+/H+ Exchanger (NHE) (nonspecified subtype) | 5-Hydroxytryptamine Receptor 3 (5-HT3 receptor) (nonspecified subtype) | T-Type Calcium Channel | Alpha-2 Adrenergic receptors (nonspecified subtype) | HTR4 | HCRTR1 | P2RX3 | Calcium-Activated K(Ca) Potassium Channel (nonspecified subtype) | SLC9A3 | ADORA1 | NPY2R | SLC9A5 | SLC6A2 | ANGPTL8 | MC3R | Orexin receptor (nonspecified subtype) | KCNK3 | PTPN1 | Voltage-Gated Sodium Channel Complex | HCRTR2 | Triacylglycerol Lipase (TG Lipase) (nonspecified subtype) | LIPC | PTGDR2 | GNRHR | G3630 | Sodium channel (nonspecified subtype) | KCNMA1 | KCNK9 | 5-Hydroxytryptamine Receptor 2 (5-HT2) (nonspecified subtype) | Muscarinic Acetylcholine Receptor (mAChR) (nonspecified subtype) | Large Conductance BK(Ca) Potassium Channel (Maxi K+ Channel) (nonspecified subtype) | SLC6A4 | alpha1-Adrenoceptor (nonspecified subtype) | LIPE | MC4R | GHRHR | TRPA1 | Melanin-concentrating hormone (MCH) receptor (nonspecified subtype) | Potassium Channels (nonspecified subtype) | LIPG | GLP1R | SLC6A3

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