Jacobsen Syndrome

About the Disease
Jacobsen Syndrome, also known as jacobsen distal 11q deletion syndrome, is related to johanson-blizzard syndrome and hypoplastic left heart syndrome, and has symptoms including muscle spasticity An important gene associated with Jacobsen Syndrome is JBS (Jacobsen Syndrome). The drugs Metformin and Hypoglycemic Agents have been mentioned in the context of this disorder. Affiliated tissues include eye, heart and kidney, and related phenotypes are intellectual disability and global developmental delay

Common Targets
CDC42

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Fetal And Neonatal Alloimmune Thrombocytopenia | Hyperparathyroidism, Secondary | Cholestasis | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Osteosarcoma | Onchocerciasis | Charcot-Marie-Tooth Disease Type 3 | Primary Progressive Aphasia | Esophageal Carcinoma | Fibrosis | Myoclonic Epilepsy With Ragged Red Fibers | Trismus-pseudocamptodactyly Syndrome | Succinic Semialdehyde Dehydrogenase Deficiency | Primary Lateral Sclerosis | Overactive Bladder | DICER1 Syndrome | Swine Influenza | Dyslexia | Multiple Epiphyseal Dysplasia | Oligoastrocytoma | Zygomycosis | Thrombocythemia, Essential | Cryptorchidism | Carey-Fineman-Ziter Syndrome | Pre-eclampsia | Neuroectodermal Tumors, Primitive | Hypersensitivity | Esophageal Motility Disorders | Bone Marrow Necrosis | Agammaglobulinemia | Hemoglobinopathies | Tic Disorder | Sepiapterin Reductase Deficiency | Glycogen Storage Disease Type 1a | Cystitis | Brugada Syndrome 1 | GLUT1 Deficiency Syndrome | Aldosterone Synthase 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