Congenital Lipoid Adrenal Hyperplasia

About the Disease
Lipoid Congenital Adrenal Hyperplasia, also known as congenital adrenal hyperplasia, is related to adrenal hyperplasia, congenital, due to steroid 11-beta-hydroxylase deficiency and adrenal hyperplasia, congenital, due to 17-alpha-hydroxylase deficiency. An important gene associated with Lipoid Congenital Adrenal Hyperplasia is STAR (Steroidogenic Acute Regulatory Protein), and among its related pathways/superpathways are Metabolism and Metapathway biotransformation Phase I and II. The drugs Prednisolone phosphate and Prednisolone acetate have been mentioned in the context of this disorder. Affiliated tissues include adrenal cortex, cortex and adrenal gland, and related phenotypes are hyperpigmentation of the skin and increased circulating acth level

Common Targets
STAR | CYP11A1 | NR5A1

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