Disease

Congenital Lipoid Adrenal Hyperplasia

About the Disease
Lipoid Congenital Adrenal Hyperplasia, also known as congenital adrenal hyperplasia, is related to adrenal hyperplasia, congenital, due to steroid 11-beta-hydroxylase deficiency and adrenal hyperplasia, congenital, due to 17-alpha-hydroxylase deficiency. An important gene associated with Lipoid Congenital Adrenal Hyperplasia is STAR (Steroidogenic Acute Regulatory Protein), and among its related pathways/superpathways are Metabolism and Metapathway biotransformation Phase I and II. The drugs Prednisolone phosphate and Prednisolone acetate have been mentioned in the context of this disorder. Affiliated tissues include adrenal cortex, cortex and adrenal gland, and related phenotypes are hyperpigmentation of the skin and increased circulating acth level

Common Targets
STAR | CYP11A1 | NR5A1

疾病靶点研报
Congenital Lipoid Adrenal Hyperplasia

Note: If you'd like to get a target analysis report for Congenital Lipoid Adrenal Hyperplasia, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Congenital Lipoid Adrenal Hyperplasia at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

MIRAGE Syndrome | Gastric Atrophy | Chorea | Spondylocostal Dysostosis | Beckwith-Wiedemann Syndrome | Erythematotelangiectatic Rosacea | Dwarfism | Pseudo-pseudohypoparathyroidism | Hyperekplexia | Exfoliative Dermatitis | Pure Autonomic Failure | Dermatitis | Saethre-Chotzen Syndrome | Polycystic Ovary Syndrome | Partington Syndrome | Pheochromocytoma | Kernicterus | Proopiomelanocortin Deficiency | Dermatomyositis | Retinal Coloboma | Torticollis | Angelman Syndrome | T-cell Prolymphocytic Leukemia | Hypoglycemia | Myasthenia | Myotonic Disorders | Swine Influenza | Cancer, Skin | Chondrodysplasia Punctata 2, X-linked Dominant | Herpes Genitalis | Spinocerebellar Ataxia Type 7 | Glomerulonephritis, Membranous | Cri-du-chat Syndrome | Myasthenia Gravis | Skin Fragility-woolly Hair Syndrome | Glomerulonephritis | Infantile Neuroaxonal Dystrophy | Thin Basement Membrane Disease | Robinow Syndrome | Open-angle Glaucoma | Gastritis | Adenosine Deaminase 2 Deficiency | Lymphoproliferative Disorders | Lesch-Nyhan Syndrome | Mevalonate Kinase Deficiency | Esophageal Motility Disorders | Duchenne Muscular Dystrophy | Nephronophthisis | Sickle Cell Disease | Hypobetalipoproteinemias | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Hamartoma | Retinal Degeneration | Glaucomatocyclitic Crisis | Pancreatitis, Chronic | Otitis Media | Spinocerebellar Ataxia Type 28 | Calcium Pyrophosphate Deposition Disease | Neutropenia | Pathological Gambling | Immunoproliferative Disorders | Pemphigoid | Hyperparathyroidism-jaw Tumor Syndrome | Diabetic Neuropathy | Poikiloderma With Neutropenia | Cholesteryl Ester Storage Disease | Familial Hypertrophic Cardiomyopathy | D-2-Hydroxyglutaric Aciduria | Congenital Hereditary Endothelial Dystrophy Type I | C3 Glomerulopathy | Apparent Mineralocorticoid Excess Syndrome | ACTH-independent Macronodular Adrenal Hyperplasia | Frank-ter Haar Syndrome | Diabetes Insipidus | Diabetes Type 2 | Dystonia-parkinsonism, X-linked | Jacobsen Syndrome | Rickets | Focal Facial Dermal Dysplasia | Chorea-acanthocytosis | Dyslexia | Waldenstrom Macroglobulinemia | Non-Hodgkin Lymphoma | Turner's Syndrome | Erysipelas | NGLY1 Deficiency | Anti-glomerular Basement Membrane Disease | Sleep Disorder | Leukoencephalopathy, Progressive Multifocal | Congenital Mirror Movements | Spinocerebellar Ataxia Type 13 | Syndactyly | Thyroid Dyshormonogenesis | FG Syndrome | Impetigo | Klippel-Feil Syndrome | 3-hydroxy-3-methylglutaric Aciduria | AIDS Dementia Complex | 3-methylglutaconic Aciduria Type I | Congenital Hemolytic Anemia | Congenital Disorders Of Glycosylation | Mohr-Tranebjaerg Syndrome | Barrett Esophagus | Pleurisy | Vertigo | Urticaria | Thymoma, Malignant | Juvenile Hyaline Fibromatosis | Conjunctivitis, Allergic | Acrodysostosis | Muckle-Wells Syndrome | Cysticercosis | Mixed Connective Tissue Disease | Macular Corneal Dystrophy Type 1 | Sleep Apnea | Osteochondroma | Multiple Sulfatase Deficiency | GLUT1 Deficiency Syndrome | Blepharospasm | Protein C Deficiency | Leiomyosarcoma | Epidermolysis Bullosa Simplex | Keratopathy | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Vascular Cognitive Impairment | WAGR Syndrome | Inflammatory Joint Disease | Ovarian Hyperstimulation Syndrome | Whipple's Disease | Autosomal Recessive Spastic Paraplegia Type 54 | Diffuse Mesangial Sclerosis | Kabuki Syndrome | Gardner Syndrome | Asthma, Nocturnal | Nephrotic Syndrome | Impulse Control Disorder | Charcot-Marie-Tooth Disease | Loeys-Dietz Syndrome Type 4 | Colitis, Collagenous | Argininosuccinic Aciduria | Analgesia | Frontometaphyseal Dysplasia | Hypertensive Nephropathy | Peritonitis | Neurofibroma, Plexiform | Niemann-Pick Disease, Type C | Waardenburg Syndrome Type 2E | Primary Hyperoxaluria Type 1 | Lyme Disease | Cryptorchidism | Nephrocalcinosis | Hypoproteinemia, Hypercatabolic | Coronary Artery Disease | Focal Dermal Hypoplasia | Sick Sinus Syndrome | Pemphigus Foliaceus | Hemophilia | Cystinuria | Chronic Idiopathic Myelofibrosis | Pemphigus Vulgaris | Cancer, Colon | Membranous Nephropathy | Diabetes | Dementia, Vascular | Japanese Encephalitis | Bronchiectasis | Spinocerebellar Ataxia Type 23 | Congenital Primary Aphakia | Woodhouse-Sakati Syndrome | Pneumonia, Viral | Nutrition Disorders | Acute Leukemia | Arthritis, Gouty | Birt-Hogg-Dube Syndrome | Constipation | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Lymphoma | Osteoporosis-pseudoglioma Syndrome | Dysequilibrium Syndrome | Erythrokeratodermia Variabilis | Glycogen Storage Disease Type 1a | Chanarin-Dorfman Syndrome | Maple Syrup Urine Disease | Primary Torsion Dystonia | Pleural Tuberculosis | Behcet's Disease | Neurocutaneous Melanocytosis | Giant Cell Arteritis | DICER1 Syndrome | Polycythemia Vera | Acrocallosal Syndrome | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Maternally Inherited Diabetes And Deafness | Cancer, Prostate | Prolymphocytic Leukemia | Genitopatellar Syndrome | Osmotic Demyelination Syndrome | Purpura, Thrombotic Thrombocytopenic | Anodontia | Chordoid Glioma | Tylosis With Esophageal Cancer | Crigler-Najjar Syndrome | Myofibrillar Myopathy | Encephalopathy | Acute Motor Axonal Neuropathy | Sarcoma, Endometrial Stromal | Mucolipidosis Type II | Alstrom Syndrome | AIDS | Retinopathy Of Prematurity | Methylmalonic Aciduria And Homocystinuria, CblC Type | Hyperlipidemia Type V | Primary Sclerosing Cholangitis | Hepatitis | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Primary Lateral Sclerosis | Jalili Syndrome | High Molecular Weight Kininogen Deficiency | Cranioectodermal Dysplasia | Angioedema | Localized Scleroderma | Hypocalcemia | Pernicious Anemia | Granular Corneal Dystrophy | Beta-Propeller Protein-associated Neurodegeneration | Renal Hypouricemia | Glutaric Aciduria Type 1 | Uveitis, Anterior | Myelitis | Benign Familial Neonatal Convulsions | Diastrophic Dysplasia | Spinal Muscular Atrophy Type 3 | Poirier-Bienvenu Neurodevelopmental Syndrome | T-cell Leukemia | Martsolf Syndrome | Hyperinsulinism-hyperammonemia Syndrome | Lymphedema | Hypertension, Renal | Geleophysic Dysplasia | Sarcoma, Ewing | Xeroderma Pigmentosum Variant Type | Esophagitis, Eosinophilic | GATA2 Deficiency | Charcot-Marie-Tooth Disease, Type 6 | Vertebrobasilar Insufficiency | Parapsoriasis | 3-methylglutaconic Aciduria Type IV | Pierpont Syndrome | Amish Infantile Epilepsy Syndrome | Rheumatoid Arthritis | Spondylocarpotarsal Synostosis Syndrome | Monilethrix | Bardet-Biedl Syndrome | Chylothorax, Congenital | Spitzoid Melanoma | Endometritis | Spinocerebellar Ataxia Type 15 | Nance-Horan Syndrome | Gnathodiaphyseal Dysplasia | Hernia, Inguinal | Guillain-Barre Syndrome | Heavy Chain Disease | Rhabdomyosarcoma, Alveolar | Spinal And Bulbar Muscular Atrophy | Cat Eye Syndrome | Hemangioma | Niemann-Pick Disease, Type B | Cornelia De Lange Syndrome | Intracerebral Hemorrhage | Panuveitis | Schizophrenia | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Epithelial-myoepithelial Carcinoma | Infantile Nephropathic Cystinosis | Danon Disease | Osteopathia Striata With Cranial Sclerosis | Leukocyte Adhesion Deficiency Type 1 | Amelanotic Melanoma | Osteosclerosis | Periodic Limb Movement Disorder | Xeroderma Pigmentosum | Pure Red Cell Aplasia | Ectrodactyly | Pulmonary Alveolar Microlithiasis | Arterial Tortuosity Syndrome | Orthostatic Intolerance | Hypercalciuria | Ehlers-Danlos Syndrome | Weill-Marchesani Syndrome | Alpha-mannosidosis | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Peeling Skin Syndrome Type B | Early Infantile Epileptic Encephalopathy 13 | Neurodegeneration With Brain Iron Accumulation | Raynaud Phenomenon | Oligoasthenoteratozoospermia | Ameloblastoma | Vitamin A Deficiency | Bladder Exstrophy | Intestinal Obstruction | Hepatitis D | Cutaneous Lupus Erythematosus | Chronic Myelomonocytic Leukemia | Sporadic Hemiplegic Migraine | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Restless Legs Syndrome | Charcot-Marie-Tooth Disease Type 2D | Leukemia | Nestor-Guillermo Progeria Syndrome | Conduct Disorder | Hypolipoproteinemia | Keratitis | Cushing Syndrome | Diarrhea | Adenoma, Pituitary | Adenylosuccinate Lyase Deficiency | Bronchitis, Chronic | Tuberculous Meningitis | Microtia | Hennekam Lymphangiectasia-lymphedema Syndrome | Hereditary Folate Malabsorption | Myhre Syndrome | Williams Syndrome | Porokeratosis | Scleroderma, Diffuse | Neurofibrosarcoma | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Odonto-onycho-dermal Dysplasia | Blood Protein Disorders | Migraine | Macular Corneal Dystrophy | McCune-Albright Syndrome | Diabetes Gestational | Congenital Adrenal Hyperplasia 1 | Ichthyosis Bullosa Of Siemens | Hemochromatosis | Cryptosporidiosis | Menetrier Disease | Bruck Syndrome | Spinocerebellar Ataxia Type 17 | Hypothalamic Obesity | Abetalipoproteinemia | Agammaglobulinemia | Aspergillosis | Idiopathic Multicentric Castleman Disease | Hyperinsulinemic Hypoglycemia | Reflex Epilepsy | Rosacea | Facioscapulohumeral Muscular Dystrophy Type 2 | Hereditary Hemorrhagic Telangiectasia | Prune Belly Syndrome | Dysfibrinogenemia | Auriculocondylar Syndrome | Stevens-Johnson Syndrome | Atrial Septal Defect | Glucagonoma | Restrictive Dermopathy | Fetal Alcohol Syndrome | Neurocysticercosis | Batten Disease | Ligneous Conjunctivitis | Achondrogenesis | Gallstones | Lewy Body Dementia | Combined Malonic And Methylmalonic Acidemia | Thyroiditis | Leukoplakia, Oral | Absence Epilepsy | Unverricht-Lundborg Syndrome | LMNA-related Congenital Muscular Dystrophy | Hydrocephalus | Hyperparathyroidism, Secondary | Spinocerebellar Ataxia Type 14 | Hypertensive Retinopathy | Sarcoidosis | Panniculitis | Neurofibroma | Lymphopenia | Hepatopulmonary Syndrome | Currarino Syndrome | Motion Sickness | Non-small Cell Lung Cancer | Holoprosencephaly | Birk-Barel Syndrome | Cardiac Arrest | Autoimmune Polyendocrinopathy Syndrome Type I | Acrodermatitis | Insulinoma | Chloridorrhea, Congenital | Sponastrime Dysplasia | DRESS Syndrome | Pompe Disease | Glycogen Storage Disease Type 6 | Spinocerebellar Ataxia | Tricho-hepato-enteric Syndrome | Optic Neuropathy | Charcot-Marie-Tooth Disease Type 4E | Benign Recurrent Intrahepatic Cholestasis 1 | Globozoospermia | Anal Fissure