Keratoconus

About the Disease
Keratoconus, also known as kc, is related to keratoconus 1 and leber congenital amaurosis 4. An important gene associated with Keratoconus is KTCN2 (Keratoconus 2), and among its related pathways/superpathways is Visual signal transduction: Cones. The drugs Gabapentin and Prednisolone phosphate have been mentioned in the context of this disorder. Affiliated tissues include Eye, endothelial and thyroid.

Common Targets
TGFBI | RAPGEF6 | GSTP1 | G7124 | G7422 | COL12A1 | CAT | PIK3CG | G6647 | SMC1B | LINC02542 | COL8A1 | IREB2 | MRGPRD | ZEB1 | PROB1 | TSC1 | MPDZ | FOXO1 | KIAA1614 | COL28A1 | PTPRD | FBN1 | CACNA1S | BANP | ASPM | TNRC6A | COX3 | ITGAX | COL8A2 | RHOBTB3 | IL1B | GLIS3 | TRNW | CYP2D6 | GLT8D2 | IL1RN | NR3C2 | MIR568 | GALNT10 | ALDH3A1 | LRRK1 | SPAM1 | FUT8 | IMMP2L | MIR583 | STARD8 | ELMO3 | GRM6 | PPIP5K2 | PLS3 | SKP1 | ND1 | MMAB | LOX | PPP3CA | MIR663B | RPS6KA6 | ATP10A | RGPD8 | TJP1 | EML6 | F3 | SPARC | SLC4A11 | CENPF | ERCC8 | LOC100652833 | CWC27 | COL5A1 | CAST | CCDC136 | FLNA | RABGEF1 | VSX1 | ARID5B | PHF2 | GPX1 | LOC105374218 | SMG7 | UBXN4 | HSPG2 | TRIM68 | MIR184 | ARVCF | APLP2 | IL17B | NFIB | SF1 | ARHGEF17 | F2 | LTBP1 | LRRN1 | LRRN3 | MAML2 | PNPLA2 | TRNH | CCNB3 | ANGPTL7 | ACOXL | BCL11B | STAB1 | ND4 | RXRA | LOXL2 | RAD51 | TGFB2 | ZNF469 | ERAP1 | LINC00578 | G4318 | WNT10A | STAG1 | ZNF543 | IL1A | COL4A3 | NOS3 | ADAMTS2 | STON2 | TTN | ARHGEF10 | MYOF | SMAD3 | QRICH2 | SAA1 | FNDC3B | G3082 | LRP1B | ND5 | ZZEF1 | KIAA0040 | PHLPP1 | RAB3GAP1 | DOCK9 | COL4A4 | HKDC1 | FOXN1 | TRNL2 | GALNT14 | LINC02692 | TRNN | NBEAL2 | IPO5 | STK24 | RUNX2-AS1 | PCSK1 | IL10 | TRNQ

Note: If you'd like to get a target analysis report for Keratoconus, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Keratoconus at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

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