Disease

Cenani-Lenz Syndactyly Syndrome

About the Disease
Cenani-Lenz Syndactyly Syndrome, also known as syndactyly type 7, is related to sclerosteosis 1 and chromosome 2q35 duplication syndrome. An important gene associated with Cenani-Lenz Syndactyly Syndrome is LRP4 (LDL Receptor Related Protein 4), and among its related pathways/superpathways are Malignant pleural mesothelioma and mTOR Signaling. Affiliated tissues include bone, kidney and bone marrow, and related phenotypes are frontal bossing and finger syndactyly

Common Targets
LRP4 | APC

疾病靶点研报
Cenani-Lenz Syndactyly Syndrome

Note: If you'd like to get a target analysis report for Cenani-Lenz Syndactyly Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Cenani-Lenz Syndactyly Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Pemphigus Foliaceus | Neurodevelopmental Disorders | Chondromyxoid Fibroma | Oculocutaneous Albinism Type 2 | Acute Tubular Necrosis | Brachial Plexus Neuropathy | Gastroschisis | Endophthalmitis | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Antenatal Bartter Syndrome Type 1 | Retinitis | Larsen Syndrome | Torticollis | Renal-hepatic-pancreatic Dysplasia | Pregnancy, Ectopic | Pneumothorax | Glaucomatocyclitic Crisis | CHOPS Syndrome | Adenosine Deaminase 2 Deficiency | Leiomyoma | Congenital Fiber-type Disproportion Myopathy | Scapuloperoneal Myopathy, X-linked Dominant | Neonatal Progeroid Syndrome | Dubin-Johnson Syndrome | Overactive Bladder | Obesity | Intermittent Explosive Disorder | Enhanced S-cone Syndrome | Kabuki Syndrome | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Joubert Syndrome | Speech Disorders | Hereditary Elliptocytosis | Okihiro Syndrome | Neurocysticercosis | Hypertriglyceridemia | Hemorrhagic Disorders | Follicular Dendritic Cell Sarcoma | Insulinoma | Mitochondrial DNA Depletion Syndrome, Myopathic Form | 3C Syndrome | Infantile Refsum Disease | Cataract | Smith-Lemli-Opitz Syndrome | Spitz Nevus | Epidermal Nevus Syndrome | Impetigo | Spinocerebellar Ataxia Type 7 | Ovarian Hyperstimulation Syndrome | Glutaric Aciduria Type 1 | Cholangitis | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Aromatic L-amino Acid Decarboxylase Deficiency | Pupil Disorders | Sandhoff Disease | Glycogen Storage Disease Type 3 | Congenital Ichthyosiform Erythroderma | Discoid Lupus Erythematosus | Hypotonia-cystinuria Syndrome | Bernard-Soulier Syndrome | Seizures-scoliosis-macrocephaly Syndrome | Myelitis, Transverse | Benign Hereditary Chorea | Dentinogenesis Imperfecta | Sleep Apnea, Obstructive | Endometriosis | Hypertension, Renal | Androgenic Alopecia | Hypoproteinemia, Hypercatabolic | Primary Familial Brain Calcification | Giant Cell Glioblastoma | Sporadic Inclusion Body Myositis | Primary Biliary Cholangitis | Hepatic Steatosis | Bethlem Myopathy | Non-epidermolytic Palmoplantar Keratoderma | Astigmatism | Idiopathic Multicentric Castleman Disease | Episodic Ataxia | Fuchs Dystrophy | DRESS Syndrome | Diverticulitis | Hypohidrotic Ectodermal Dysplasia, X-linked | Basal Ganglia Disease, Biotin-responsive | Acrodermatitis | Personality Disorders | Epilepsy Of Infancy With Migrating Focal Seizures | Inflammatory Myopathy | Thrombasthenia | Carcinoma In Situ | Sialidosis Type I | Hyperglycemia | Early Infantile Epileptic Encephalopathy 13 | Erythromelalgia | Skin Papilloma | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Granular Corneal Dystrophy Type 1 | Addison Disease | Protein C Deficiency | Chorioretinitis | Thrombophilia | Autoimmune Polyendocrinopathy Syndrome Type I | Ichthyosis | Tylosis With Esophageal Cancer | Isobutyryl-CoA Dehydrogenase Deficiency | Melanoma | Spinocerebellar Ataxia Type 3 | Waardenburg Syndrome Type 1 | Nicotine Dependence | Epithelioid Hemangioma | Postaxial Polydactyly | Diabetes Type 1 | Spinocerebellar Ataxia Type 27 | Persistent Mullerian Duct Syndrome | Peritonitis | Diastrophic Dysplasia | Rothmund-Thomson Syndrome | Urticaria | Autonomic Neuropathy | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Persistent Hyperplastic Primary Vitreous | Auriculocondylar Syndrome | Hyperlipidemia, Familial Combined | Spinocerebellar Ataxia Type 31 | Graves Disease | Pneumonia, Bacterial | HUPRA Syndrome | Holoprosencephaly | Keratoconus | Ichthyosis Bullosa Of Siemens | Progressive Myoclonic Epilepsy | Ligneous Conjunctivitis | Leishmaniasis, Cutaneous | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Neurotoxicity | Ellis-Van Creveld Syndrome | Hemochromatosis Type 1 | Potocki-Shaffer Syndrome | Anthrax | Methylmalonic Acidemia | Succinic Semialdehyde Dehydrogenase Deficiency | Hereditary Xerocytosis | Retinitis Pigmentosa 3 | Azoospermia | Dent Disease | Glutaric Aciduria Type 2 | Myopathy | Amebiasis | AIDS | REM Sleep Behavior Disorder | Carcinoma, Merkel Cell | GLUT1 Deficiency Syndrome | Amyotrophic Lateral Sclerosis, Juvenile | Oral Lichen Planus | Lassa Fever | Anorexia Nervosa | Bacterial Meningitis | Gnathodiaphyseal Dysplasia | Schuurs-Hoeijmakers Syndrome | Congenital Primary Aphakia | Pontocerebellar Hypoplasia Type 7 | LMNA-related Congenital Muscular Dystrophy | Paroxysmal Kinesigenic Dyskinesia | Endometrial Hyperplasia | Thyroid Hormone Resistance | Lung Diseases | Gerstmann-Straussler-Scheinker Syndrome | Keratoacanthoma | Basal Cell Nevus Syndrome | Carbamoyl Phosphate Synthetase I Deficiency | Cerebellar Ataxia, Cayman Type | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Polycystic Kidney, Autosomal Recessive | Schwannomatosis | Pulmonary Veno-occlusive Disease | Acrocallosal Syndrome | Avian Influenza | Pearson Syndrome | Neutrophilia | Macrophage Activation Syndrome | Spondylometaphyseal Dysplasia | Cluster Headache | Tic Disorder | Cystinuria | Batten Disease | Peeling Skin Syndrome Type B | Spinocerebellar Ataxia Type 16 | Best Macular Dystrophy | Hereditary Hemorrhagic Telangiectasia Type 2 | Persistent Fetal Circulation | Combined Malonic And Methylmalonic Acidemia | Mucolipidosis | Otopalatodigital Syndrome Type 2 | Incontinentia Pigmenti | Encephalopathy | Diabetes Type 2 | Congenital Muscular Dystrophy | Tyrosinemia Type 2 | Optic Atrophy 2 | Facioscapulohumeral Muscular Dystrophy | Chordoid Glioma | Glycogen Storage Disease Type 1b | Crisponi Syndrome | Hypertension, Pulmonary | Spondylocostal Dysostosis | Fabry's Disease | Infertility, Male | Pseudohypoparathyroidism Type 1C | Galactosemia | Erectile Dysfunction | IgA Nephropathy | Campomelic Dysplasia | X-linked Sideroblastic Anemia | Spinocerebellar Ataxia Type 21 | Sarcoidosis, Pulmonary | Congenital Nephrotic Syndrome | Japanese Encephalitis | Benign Recurrent Intrahepatic Cholestasis 1 | Cramp Fasciculation Syndrome | Lichen Sclerosus | Raine Syndrome | Schizophrenia, Paranoid | Depression | Microvillus Inclusion Disease | Hemangioblastoma | Hereditary Multiple Exostoses | Prediabetes | Fatty Aldehyde Dehydrogenase Deficiency | Hyperuricemia | Colitis, Microscopic | Carcinoid Tumor | Pseudohypoparathyroidism Type 2 | Ebstein Anomaly | Neuroleptic Malignant Syndrome | Stromal Corneal Dystrophy | Tuberculosis | Hypereosinophilic Syndrome | Leukodystrophies | Macular Corneal Dystrophy | Hydrops Fetalis | Mastitis | Oculocutaneous Albinism Type 4 | Prader-Willi Syndrome | Multiple System Atrophy | Corneal Dystrophy And Perceptive Deafness | Cancer, Skin | MELAS Syndrome | Adenomatoid Tumor | Senior-Loken Syndrome | Multiple Myeloma | Vascular Calcification | Hydrocephalus, Normal Pressure | Poirier-Bienvenu Neurodevelopmental Syndrome | Bartsocas-Papas Syndrome | Beta-Propeller Protein-associated Neurodegeneration | Encephalitis, Tick-borne | Neurofibrosarcoma | Tietze Syndrome | Congenital Afibrinogenemia | Oculopharyngeal Muscular Dystrophy | Aldosterone Deficiency | Dementia | HELLP Syndrome | Crouzon Syndrome With Acanthosis Nigricans | Arterial Tortuosity Syndrome | Usher Syndrome Type IIC | Tumoral Calcinosis | Hepatitis | Giant Axonal Neuropathy | Herpes Genitalis | Fontaine Progeroid Syndrome | Infantile Spasm | Lymphedema | Multiple Sclerosis, Chronic Progressive | Exotropia | Platelet Disorders | Lymphoma, AIDS-related | Alcoholism | Macular Degeneration | Bone Marrow Necrosis | Spinocerebellar Ataxia Type 10 | Leber Congenital Amaurosis | Deafness, Dystonia, And Cerebral Hypomyelination | Hyperuricemic Nephropathy, Familial Juvenile | Pneumonia, Viral | Limb Girdle Muscular Dystrophy | Conjunctivitis | Hepatitis D | Basan Syndrome | Anorchia | Hereditary Neuropathy With Liability To Pressure Palsies | Cancer, Lung | Pernicious Anemia | Esophagitis, Eosinophilic | Irritable Bowel Syndrome | Carey-Fineman-Ziter Syndrome | Pulmonary Capillary Hemangiomatosis | Hyperandrogenemia | Pheochromocytoma | Diabetes Insipidus, Nephrogenic | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Genitopatellar Syndrome | Corneal Neovascularization | Wolff-Parkinson-White Syndrome | Purpura | Cancer, Colon | Keratitis-ichthyosis-deafness Syndrome | Esophageal Adenocarcinoma | Urolithiasis | Multiple Sulfatase Deficiency | Periodontitis | Sarcomatoid Carcinoma Of The Lung | Optic Neuritis | Gastroenteritis | Multifocal Motor Neuropathy | Chronic Leukemia | Macular Corneal Dystrophy Type 1 | Proctitis | Pulmonary Sclerosing Hemangioma | Split Hand-foot Malformation | Myopia | Prolidase Deficiency | Long QT Syndrome Type 1 | Focal Dermal Hypoplasia | Hereditary Folate Malabsorption | Hypotrichosis | Conn Syndrome | Vitamin B12 Deficiency | Blepharospasm | Turner's Syndrome | Sleep Disorder | Periodic Limb Movement Disorder | Central Core Disease | Paronychia | Waardenburg Syndrome Type 2E | Thyroiditis | Growth Hormone Excess | Shwachman-Bodian-Diamond Syndrome | Emery-Dreifuss Muscular Dystrophy | Metaphyseal Chondrodysplasia, Schmid Type | Alpha-mannosidosis | Niemann-Pick Disease, Type A | Aicardi-Goutieres Syndrome | Barrett Esophagus | Common Variable Immunodeficiency | Pituitary Disorders | Necrotizing Autoimmune Myopathy | Cutis Laxa | Thalassemia | Infectious Diarrhea | Colon Adenoma | Sweet Syndrome | Miyoshi Myopathy | Chondroma | Stuve-Wiedemann Syndrome | Androgen Insensitivity | Skin Fragility-woolly Hair Syndrome | Hypotension, Orthostatic | DNA Ligase IV Deficiency | Dyslipidemia | Analgesia | Imerslund-Grasbeck Syndrome | Congenital Nystagmus | Lymphoproliferative Disorders | Megalencephaly | Niemann-Pick Disease, Type C | Oligoastrocytoma | Congenital Heart Block | Conjunctivitis, Allergic | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Chordoma | Juvenile Myelomonocytic Leukemia | Proteasome-associated Autoinflammatory Syndrome 2 | Leprosy | Costello Syndrome | X-linked Creatine Transporter Deficiency | Sepiapterin Reductase Deficiency | Becker Muscular Dystrophy | Achondrogenesis | Localized Scleroderma | Seborrheic Dermatitis | Maple Syrup Urine Disease | Spinocerebellar Ataxia Type 15 | Glutaric Aciduria Type 3 | Zellweger Syndrome | Cholecystitis | Fetal And Neonatal Alloimmune Thrombocytopenia | Otosclerosis | Lattice Corneal Dystrophy Type 1 | Generalized Epilepsy With Febrile Seizures Plus | Congenital Dyserythropoietic Anemia Type 1 | Acrodysostosis | Epidermolytic Ichthyosis, Annular | Asplenia | Congenital Adrenal Hyperplasia 1 | Chloridorrhea, Congenital | Mood Disorder | Fibrodysplasia Ossificans Progressiva | Vertigo | Multicystic Renal Dysplasia