Cenani-Lenz Syndactyly Syndrome

About the Disease
Cenani-Lenz Syndactyly Syndrome, also known as syndactyly type 7, is related to sclerosteosis 1 and chromosome 2q35 duplication syndrome. An important gene associated with Cenani-Lenz Syndactyly Syndrome is LRP4 (LDL Receptor Related Protein 4), and among its related pathways/superpathways are Malignant pleural mesothelioma and mTOR Signaling. Affiliated tissues include bone, kidney and bone marrow, and related phenotypes are frontal bossing and finger syndactyly

Common Targets
LRP4 | APC

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Progressive Myoclonic Epilepsy | Primary Progressive Nonfluent Aphasia | Benign Familial Pemphigus | Renal Failure | Diabetic Neuropathy | Melanocytic Nevus | Goldenhar Syndrome | Cystitis, Interstitial | Metanephric Adenoma | Hypospadias | Acrodermatitis Enteropathica | Hemolytic Uremic Syndrome, Atypical | Prediabetes | Cavitary Optic Disc Anomalies | Pseudohypoparathyroidism Type 1C | Paternal Uniparental Disomy Of Chromosome 14 | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Diabetes Mellitus, Transient Neonatal | Eclampsia | Cystinuria | Maternally Inherited Diabetes And Deafness | Rhabdoid Tumor | Rhinitis | Mucolipidosis Type IV | Corneal Dystrophy | Congenital Hypofibrinogenemia | Achromatopsia | Congenital Nephrotic Syndrome | Coronary Artery Disease | Thyroiditis | Intracranial Hypertension | T-cell Lymphoma, Subcutaneous Panniculitis-like | Encephalopathy, Ethylmalonic | Charcot-Marie-Tooth Disease Type 2D | Thyroid Dysgenesis | DOCK8 Immunodeficiency Syndrome | Panuveitis | Angioimmunoblastic T-cell Lymphoma | Waldenstrom Macroglobulinemia | Graves Disease | Neuronal Ceroid Lipofuscinosis | Intestinal Obstruction | Congenital Sodium Diarrhea | Inflammatory Myopathy | Lymphangioma | Lafora Disease | Fetal Akinesia Deformation Sequence | Barrett Esophagus | Gnathodiaphyseal Dysplasia | Autoimmune Polyendocrinopathy Syndrome Type I | Chorea | Paroxysmal Nocturnal Hemoglobinuria | Anemia | Glutaric Aciduria Type 2 | Congenital Absence Of Vas Deferens | T-cell Chronic Lymphocytic Leukemia | Postpartum Depression | Hepatoblastoma | Fibromyalgia | McCune-Albright Syndrome | Growth Hormone Excess | Prostatitis | Citrullinemia | Spinocerebellar Ataxia Type 21 | Pendred Syndrome | Schnitzler Syndrome | Neurofibromatosis-Noonan Syndrome | Skin Fragility-woolly Hair Syndrome | Splenomegaly | Syncope | Spondyloepiphyseal Dysplasia Tarda, X-linked | Hereditary Mixed Polyposis Syndrome | Polycythemia | Papulopustular Rosacea | Waardenburg Syndrome Type 2 | Chromosome 5q Deletion Syndrome | Spinocerebellar Ataxia Type 38 | Bipolar Disorder | Myasthenia Gravis | Chronic Leukemia | Peutz-Jeghers Syndrome | Blepharophimosis Syndrome | Isobutyryl-CoA Dehydrogenase Deficiency | Tyrosinemia Type 2 | Chitayat Syndrome | Spermatocele | Bone Marrow Necrosis | Uterine Leiomyoma | Renal Medullary Carcinoma | Dystonia Musculorum Deformans | Neuroendocrine Cancer | Ventricular Septal Defect | Meier-Gorlin Syndrome | Bainbridge-Ropers Syndrome | Hypercholesterolemia | Birt-Hogg-Dube Syndrome | Hypothalamic Obesity | Prolactinoma | Generalized Epilepsy And Paroxysmal Dyskinesia | Pleomorphic Xanthoastrocytoma | Apert Syndrome | Phenylketonuria | Hypertension, Portal | Beta-Propeller Protein-associated Neurodegeneration | Migraine | Gestational Trophoblastic Disease | Carbohydrate Metabolism Disorders | Prurigo Nodularis | Hemophilia | Acromesomelic Dysplasia | Contact Dermatitis | Epicondylitis | Delayed Sleep Phase Syndrome | DRESS 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